Tailored raman spectrocopic probes for ultrasensitive and highly multiplexed assays
    1.
    发明授权
    Tailored raman spectrocopic probes for ultrasensitive and highly multiplexed assays 有权
    定制的拉曼光谱探针用于超敏感和高度多重测定

    公开(公告)号:US08873038B2

    公开(公告)日:2014-10-28

    申请号:US13277674

    申请日:2011-10-20

    Abstract: Embodiments of nanostructured, multilayered metal-dielectric particles suitable for use as Raman spectroscopic probes are disclosed, as well as methods of designing, making and using such multilayered nanoparticles, and kits including the multilayered nanoparticles. The multilayered nanoparticles include alternating metal and dielectric layers and an outer dielectric shell. One or more of the dielectric layers may include a plurality of reporter molecules. Embodiments of the multilayered nanoparticles are suitable for detecting target analytes in a sample. Some embodiments of the multilayered nanoparticles are suitable for use in multiplexed assays, including assays for multiple target analytes having differing concentrations.

    Abstract translation: 公开了适合用作拉曼光谱探针的纳米结构多层金属 - 电介质颗粒的实施方案,以及设计,制备和使用这种多层纳米颗粒的方法,以及包括多层纳米颗粒的试剂盒。 多层纳米颗粒包括交替的金属和电介质层和外部电介质外壳。 介电层中的一个或多个可包括多个报道分子。 多层纳米颗粒的实施方案适用于检测样品中的目标分析物。 多层纳米颗粒的一些实施方案适用于多重测定,包括具有不同浓度的多种目标分析物的测定。

    TAILORED RAMAN SPECTROCOPIC PROBES FOR ULTRASENSITIVE AND HIGHLY MULTIPLEXED ASSAYS
    2.
    发明申请
    TAILORED RAMAN SPECTROCOPIC PROBES FOR ULTRASENSITIVE AND HIGHLY MULTIPLEXED ASSAYS 有权
    用于超声波和高度多重测试的定制拉曼光谱探测器

    公开(公告)号:US20120212733A1

    公开(公告)日:2012-08-23

    申请号:US13277674

    申请日:2011-10-20

    Abstract: Embodiments of nanostructured, multilayered metal-dielectric particles suitable for use as Raman spectroscopic probes are disclosed, as well as methods of designing, making and using such multilayered nanoparticles, and kits including the multilayered nanoparticles. The multilayered nanoparticles include alternating metal and dielectric layers and an outer dielectric shell. One or more of the dielectric layers may include a plurality of reporter molecules. Embodiments of the multilayered nanoparticles are suitable for detecting target analytes in a sample. Some embodiments of the multilayered nanoparticles are suitable for use in multiplexed assays, including assays for multiple target analytes having differing concentrations.

    Abstract translation: 公开了适合用作拉曼光谱探针的纳米结构多层金属 - 电介质颗粒的实施方案,以及设计,制备和使用这种多层纳米颗粒的方法,以及包括多层纳米颗粒的试剂盒。 多层纳米颗粒包括交替的金属和电介质层和外部电介质外壳。 介电层中的一个或多个可包括多个报道分子。 多层纳米颗粒的实施方案适用于检测样品中的目标分析物。 多层纳米颗粒的一些实施方案适用于多重测定,包括具有不同浓度的多种目标分析物的测定。

    Methods and systems for computer based collaboration
    3.
    发明申请
    Methods and systems for computer based collaboration 有权
    用于计算机协作的方法和系统

    公开(公告)号:US20050276479A1

    公开(公告)日:2005-12-15

    申请号:US11119636

    申请日:2005-05-02

    CPC classification number: G06F17/27 G06Q10/10

    Abstract: An exemplary method for computer based collaboration between a plurality of participants communicating over a data network comprises steps of receiving communications data with the computer, using a text analysis tool to identify at least a plurality of k-words from the communications data and a plurality of relations linking at least a portion of the plurality of k-words, and displaying the k-words and relations to the plurality of participants over the computer network.

    Abstract translation: 用于通过数据网络通信的多个参与者之间的基于计算机的协作的示例性方法包括以下步骤:使用文本分析工具从计算机接收通信数据,以从通信数据中识别至少多个k个字,以及多个 连接多个k个字的至少一部分的关系,以及通过计算机网络向多个参与者显示k个词和关系。

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