公开(公告)号：US20240307577A1

公开(公告)日：2024-09-19

申请号：US18576785

申请日：2022-07-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Stephen B. Roscoe ,  George W. Griesgraber ,  Tonya D. Bonilla ,  Giuseppe M. Bommarito ,  Wensheng Xia ,  Jeffrey M. Flynn

IPC: A61L2/28 ,  A61L2/16 ,  C07H17/075 ,  C09K11/06 ,  C12Q1/22

CPC classification number: A61L2/28 ,  A61L2/16 ,  C07H17/075 ,  C09K11/06 ,  C12Q1/22

Abstract: A chlorinated 4′-alkylumbelliferyl α-D-glucopy-ranoside represented by the structural formula (I) One of R1 and R2 is Cl and the other is H. R3 represents an alkyl group having 1 to 12 carbon atoms. A method of assessing efficacy of a sterilization process including the same is also disclosed.

公开(公告)号：US11884662B2

公开(公告)日：2024-01-30

申请号：US17250073

申请日：2019-05-23

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： George W. Griesgraber ,  Hannah C. Cohen ,  Jana Ninkovic

IPC: C07D471/04 ,  A61P37/02 ,  A61K31/4745

CPC classification number: C07D471/04 ,  A61K31/4745 ,  A61P37/02

Abstract: Imidazo[4,5-c]quinoline compounds of Formula (I) having a substituent that is attached at the N−1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.

公开(公告)号：US20230406855A1

公开(公告)日：2023-12-21

申请号：US18251578

申请日：2021-10-15

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： George W. Griesgraber ,  Mark A. Tomai ,  Hannah C. Cohen ,  Devon M. Hunerdosse

IPC: C07D471/04 ,  A61K47/54

CPC classification number: C07D471/04 ,  A61K47/545

Abstract: Imidazoquinoline compounds, salts thereof, conjugates thereof, pharmaceutical compositions containing the compounds and conjugates, and methods of use of such compounds as immune response modifiers, for inducing cytokine biosynthesis in humans and animals.

公开(公告)号：US11576845B2

公开(公告)日：2023-02-14

申请号：US16475260

申请日：2018-01-02

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ranjani V. Parthasarathy ,  Ramesh C. Kumar ,  Matthew T. Scholz ,  Steven P. Swanson ,  Andrew W. Vail ,  Jerald K. Rasmussen ,  George W. Griesgraber ,  Catherine D. Heapy

IPC: C11D7/22 ,  A61K8/02 ,  A01N25/10 ,  A01N31/02 ,  A01N47/44 ,  A61K8/34 ,  A61K8/81 ,  A61K8/84 ,  A61L2/00 ,  A61Q17/00

Abstract: Disclosed herein are methods that include contacting a skin surface with a first liquid composition; and then contacting in the skin surface with a cationic coated article loaded with a second liquid composition, while at least some portion of the first liquid composition remains on the skin surface, wherein one or both of the first liquid composition or the second liquid composition includes acrylate copolymer particles dispersed therein, the acrylate copolymer particles including the reaction product of a reaction mixture, the reaction mixture including monomers, the monomers including from about 5 wt % to about 50 wt % of at least one high Tg monomer where the wt % of the high Tg monomer is with respect to the total weight of the monomers in the reaction mixture; and from about 20 wt % to about 80 wt % of at least one low Tg monomer where the wt % of the low Tg monomer is with respect to the total weight of the monomers in the reaction mixture, wherein the particles have a number average diameter of at least about 100 nm and wherein at least one and only one of the first or the second composition comprises greater than or equal to 60 wt % of at least one alcohol.

公开(公告)号：US20220363801A1

公开(公告)日：2022-11-17

申请号：US17753262

申请日：2020-09-11

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Semra Colak Atan ,  Federica Sgolastra ,  George W. Griesgraber

IPC: C08F293/00 ,  C09D153/00

Abstract: A block copolymer is provided that includes a first block having pendant phosphate and/or phosphonate groups and a second block that contains pendant poly(dialkylsiloxane) groups. Compositions containing the block copolymer as well as articles that include the block copolymer are also provided. The block copolymer can be used to provide a surface that is easy to clean and/or that is resistant to oil and grease without the use of fluorinated materials.

公开(公告)号：US11446613B2

公开(公告)日：2022-09-20

申请号：US16328389

申请日：2017-08-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Andrew W. Vail ,  Semra Colak Atan ,  Jerald K. Rasmussen ,  George W. Griesgraber ,  Catherine A. Bothof

IPC: B01D71/00 ,  B01D69/00 ,  C07K1/34 ,  B01D71/40 ,  B01D69/02 ,  B01D69/12 ,  B01D71/78 ,  C07K16/00 ,  C09D133/26 ,  B01D67/00

Abstract: An article that includes a functionalized copolymer and the use thereof, particularly in a process for binding biomaterials, such as in a process for separating aggregated proteins from monomeric proteins in a biological solution; wherein the article includes: a) a porous substrate; and b) a copolymer covalently attached to the porous substrate, the copolymer comprising a hydrocarbon backbone and a plurality of pendant groups attached to the hydrocarbon backbone, wherein 1) each of a first plurality of pendant groups comprises: (a) at least one acidic group or salt thereof; and (b) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and 2) each of a second plurality of pendant groups comprises: (a) at least one acidic group or salt thereof; and (b) a spacer group that directly links the at least one acidic group or salt thereof to the hydrocarbon backbone by a chain of at least 6 catenated atoms; and wherein the first plurality of pendant groups are different than the second plurality of pendant groups; and wherein a mole ratio of the first plurality of pendant groups to the second plurality of pendant groups is in a range of 95:5 to 5:95.

公开(公告)号：US20220177471A1

公开(公告)日：2022-06-09

申请号：US17594415

申请日：2020-05-27

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： George W. Griesgraber ,  Michael J. Rice ,  Hannah C. Cohen ,  Devon M. Hunerdosse ,  Adam D. Miller ,  Joshua R. Wurst

IPC: C07D471/04

Abstract: Imidazo[4,5-c]quinoline compounds having a substituent that is attached at the N-1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing (or inhibiting) cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.

公开(公告)号：US20210095097A1

公开(公告)日：2021-04-01

申请号：US15733169

申请日：2018-12-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kevin M. Lewandowski ,  Stephen B. Roscoe ,  Babu N. Gaddam ,  Bryan T. Whiting ,  John L. Battiste ,  George W. Griesgraber

IPC: C08K5/39 ,  C08F2/38 ,  C08F2/50 ,  C08F220/18 ,  C08F236/20

Abstract: Controlled radical initiators, reaction mixtures containing the controlled radical initiators and various ethylenically unsaturated monomers, polymeric materials formed from the reaction mixtures, crosslinkable compositions containing the polymeric materials, crosslinked compositions formed from the crosslinkable compositions, and articles containing the polymeric materials, the crosslinkable compositions, or the crosslinked compositions are provided. The controlled radical initiators are bis-dithiocarbamate or bis-dithiocarbonate compounds having a single carbon between the two dithiocarbamate or dithiocarbonate groups. Also attached to that single carbon is a ketone group.

公开(公告)号：US20210095088A1

公开(公告)日：2021-04-01

申请号：US15733171

申请日：2018-12-14

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Stephen B. Roscoe ,  Babu N. Gaddam ,  George W. Griesgraber ,  Daniel J. O'Neal ,  Eli Narveson

IPC: C08J7/18 ,  C08J7/12 ,  C08G75/26

Abstract: First articles with covalently attached thiocarbonylthio-containing groups are provided. More specifically, the first articles are a functionalized substrate that contains a solid polymeric substrate with a plurality of thiocarbonylthio-containing groups covalently attached directly to carbon atoms in a polymeric backbone of the solid polymeric substrate. Methods of making the first articles with covalently attached thiocarbonylthio-containing groups are provided. Additionally, second articles and methods of using the first articles to generate second articles with covalently attached polymeric chains are provided.

公开(公告)号：US20200368694A1

公开(公告)日：2020-11-26

申请号：US15733205

申请日：2018-12-14

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Stephen B. Roscoe ,  Babu N. Gaddam ,  George W. Griesgraber ,  Daniel J. O'Neal ,  Eli P. Narveson

IPC: B01D67/00 ,  C08J7/18 ,  G01N33/543 ,  G01N33/545 ,  C12M1/00 ,  B01D69/02 ,  B01D69/10

Abstract: Articles with covalently attached thiocarbonylthio-containing groups are provided. More specifically, the articles include a solid polymeric substrate with a plurality of thiocarbonylthio-containing groups covalently attached directly to a carbon atom in a polymeric backbone of the solid polymeric substrate. Methods of making the articles with covalently attached thiocarbonylthio-containing are provided. Additionally, methods of using these articles to generate further articles with covalently attached polymeric chains are provided.