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公开(公告)号：US11827754B2
公开(公告)日：2023-11-28
申请号：US16338776
申请日：2017-10-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jason W. Bjork , Amy S. Determan , Jonathan J. O'Hare , Robert A. Asmus , James P. Dizio , Zhicheng Tian
CPC classification number: C08J3/075 , C08L89/00 , C08J2389/00 , C08J2439/04
Abstract: Provided is a method of forming a fibrin hydrogel composition, the method including providing a fibrin hydrogel or precursor thereof, comprising fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further includes combining the fibrin hydrogel with a carrier material. The concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrin hydrogel.
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公开(公告)号：US10940233B2
公开(公告)日：2021-03-09
申请号：US16338803
申请日：2017-10-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： James P. Dizio , Zhicheng Tian , Jason W. Bjork , Amy S. Determan , Robert A. Asmus , Jonathan J. O'Hare
IPC: A61L26/00
Abstract: Provided is a method of forming a fibrinogen hydrogel composition, the method including providing a fibrinogen hydrogel or precursor thereof, comprising fibrinogen hydrogel forming salt. The fibrinogen hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrinogen hydrogel. The method further includes denaturing the fibrinogen hydrogel such as by heating. The method optionally further includes combining the fibrinogen hydrogel with a carrier material. When present, the concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrinogen hydrogel.
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Patent Agency Ranking
公开(公告)号：US10723894B2
公开(公告)日：2020-07-28
申请号：US15537714
申请日：2015-12-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Lan H. Liu , Audrey A. Sherman , Haeen Sykora , Joan M. Noyola , Sonja S. Mackey , James P. Dizio
Abstract: Waterborne suspensions include surface treated silica particles, a water dispersable binder resin, at least one surfactant, and an aqueous solvent. The surface treated silica particles have a mixture of hydrophobic and hydrophilic silane surface treatment agents, where the ratio of hydrophilic silane surface treatment agent to hydrophobic silane surface treatment agent is greater than 1. The waterborne suspensions can be coated and dried to form nanostructured tie layers, especially tie layers to silicone or (meth)acrylate layers.
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公开(公告)号：US12060502B2
公开(公告)日：2024-08-13
申请号：US17057841
申请日：2019-05-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Encai Hao , Zhicheng Tian , Dong-Wei Zhu , Zhaohui Yang , James P. Dizio , Ying Zhang , Junkang J. Liu , Kent C. Hackbarth
IPC: C09J151/08 , C08F220/18 , C08F283/12 , C08L33/08 , C09J11/08 , C09J133/08 , H10K50/844 , H10K50/00 , H10K50/10 , H10K50/80 , H10K50/842 , H10K59/10 , H10K59/12
CPC classification number: C09J151/08 , C08F220/1808 , C08F283/12 , C08L33/08 , C09J11/08 , C09J133/08 , C09J151/085 , H10K50/844 , H10K50/00 , H10K50/10 , H10K50/8426 , H10K50/868 , H10K59/10 , H10K59/12 , C08F220/1808 , C08F220/56 , C08F220/1808 , C08F218/08 , C08F220/56 , C08F283/12 , C08F220/1808 , C08F220/56 , C08F283/12 , C08F220/1808 , C08F220/56 , C08F218/08
Abstract: Phase separated articles that include a matrix phase including an acrylate copolymer; and a silicone elastomer phase stably dispersed in the matrix phase are described. The matrix phase may be derived from precursors comprising from 60 to 95 parts by weight of an alkyl acrylate having an alkyl group having 1 to 14 carbon atoms. Methods of forming phase separated articles, and articles including phase separated articles are also described.
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公开(公告)号：US10941252B2
公开(公告)日：2021-03-09
申请号：US16345809
申请日：2017-10-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Hannah C. Cohen , Amanda C. Engler , Ranjani V. Parthasarathy , Haoming Rong , Ramesh C. Kumar , Matthew T. Scholz , James P. Dizio , Audrey A. Sherman , Richard G. Hansen , Douglas A. Hanggi , Dale J. Case , David Duane Johnson
IPC: C08G77/46 , C08G77/458 , C08K5/00 , C08G64/18
Abstract: A copolymer composition that includes a silicone copolymer, methods of making the composition, and articles that include the composition, wherein the copolymer composition includes a silicone copolymer having a backbone composition that includes: silicone segments in an amount of 5 wt-% to 40 wt-%, based on the total weight of the silicone copolymer; hydrophilic segments in an amount of 40 wt-% to 75 wt-%, based on the total weight of the silicone copolymer; and reinforcing segments in an amount of 5 wt-% to 30 wt-%, based on the total weight of the silicone copolymer, wherein the reinforcing segments are derived from the reaction of one or more chain extenders with one or more multi-functional isocyanates, multi-functional carboxylic acids, multi-functional anhydrides, multi-functional esters, and/or multi-functional acid halides; wherein the silicone segments, hydrophilic segments, and reinforcing segments are connected through urea, urethane, amide, and/or oxamide linkages; wherein the hydrophilic segments and the reinforcing segments are present in a weight ratio of 1.8:1 to 8:1; and the hydrophilic segments and the silicone segments are present in a weight ratio of 1.3:1 to 4.5:1.
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公开(公告)号：US10034840B2
公开(公告)日：2018-07-31
申请号：US15168270
申请日：2016-05-31
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： James P. Dizio , Elizabeth E. Johnson , Zheng Z. Wu , Amy Preszler Prince
IPC: A61K9/70 , A61K31/165 , C09J4/06 , C09J133/08 , C09J133/10 , A61K31/27 , A61L24/06 , C08F220/18 , C08F220/56 , C08F218/08
CPC classification number: A61K9/7061 , A61K31/165 , A61K31/27 , A61L24/06 , C08F220/18 , C08F2220/1858 , C09J4/06 , C09J133/08 , C09J133/10 , C08F218/08 , C08F220/56
Abstract: A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; and at least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.
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公开(公告)号：US20180037754A1
公开(公告)日：2018-02-08
申请号：US15537714
申请日：2015-12-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Lan H. Liu , Audrey A. Sherman , Haeen Sykora , Joan M. Noyola , Sonja S. Mackey , James P. Dizio
IPC: C09D7/12 , C09D133/06 , C09C1/30 , C09D5/00
CPC classification number: C09D7/62 , C01P2004/64 , C01P2006/12 , C08K3/36 , C08K9/06 , C09C1/3081 , C09D5/002 , C09D5/006 , C09D5/028 , C09D133/06
Abstract: Waterborne suspensions include surface treated silica particles, a water dispersable binder resin, at least one surfactant, and an aqueous solvent. The surface treated silica particles have a mixture of hydrophobic and hydrophilic silane surface treatment agents, where the ratio of hydrophilic silane surface treatment agent to hydrophobic silane surface treatment agent is greater than 1. The waterborne suspensions can be coated and dried to form nanostructured tie layers, especially tie layers to silicone or (meth)acrylate layers.
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