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公开(公告)号：US09662231B2
公开(公告)日：2017-05-30
申请号：US13840257
申请日：2013-03-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Michael Huy Ngo , Samit Mustafa , Syed Hossainy , Mikael Trollsas
CPC classification number: A61F2/82 , A61F2/915 , A61F2002/91575 , B29C49/08 , B29C55/26 , B29C2793/0009 , B29L2031/753 , B29L2031/7542 , Y10T29/49863
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a morphology resulting from a biaxially expanded tube arranged to provide a more balanced, or less anisotropic axial and radial mechanical properties. The scaffold has improved mechanical properties suited for use as a balloon expandable scaffold implanted in a peripheral vessel of the body.
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公开(公告)号：US08865189B2
公开(公告)日：2014-10-21
申请号：US13731875
申请日：2012-12-31
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy , O. Mikael Trollsas , Michael Huy Ngo
CPC classification number: A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
Abstract: Implantable medical devices including a coating having a bioactive agent and a poly(ester amide) polymer. Methods of forming these coatings are also described.
Abstract translation: 可植入医疗装置，包括具有生物活性剂和聚（酯酰胺）聚合物的涂层。 还描述了形成这些涂层的方法。
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公开(公告)号：US20140277331A1
公开(公告)日：2014-09-18
申请号：US13801691
申请日：2013-03-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Michael Huy Ngo , Benjamyn Serna , Mikael Trollsas , Syed Hossainy
IPC: A61F2/958
CPC classification number: A61F2/958 , A61F2/0095 , A61F2250/0085 , A61F2250/0097
Abstract: A peripherally implanted polymer scaffold having a high degree of recoil is worked to reduce recoil in the scaffold when initially deployed at a target lesion in the body. The scaffold is plastically deformed from a crimped state to an expanded state by a balloon catheter. The scaffold is contained within a sheath to prevent recoil up until the point of use. Before the scaffold is introduced to the body, the restraining sheath is removed from the scaffold.
Abstract translation: 当最初部署在体内的目标损伤时，加工具有高度后坐力的外周植入聚合物支架以减少支架中的反冲。 支架通过气囊导管从卷曲状态塑性变形到膨胀状态。 支架被包含在护套内以防止反冲直到使用点。 在将脚手架引入身体之前，将约束护套从支架上移除。
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公开(公告)号：US20140127279A1
公开(公告)日：2014-05-08
申请号：US14152867
申请日：2014-01-10
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael Huy Ngo , David J. Sherman , Syed Faiyaz Ahmed Hossainy
IPC: A61K47/34
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
Abstract translation: 本发明提供具有包含缓慢溶解性聚合物或材料的涂层的可植入装置及其制造和使用方法。
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公开(公告)号：US20130230564A1
公开(公告)日：2013-09-05
申请号：US13770988
申请日：2013-02-19
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Lothar W. Kleiner , Yiwen Tang , Syed Faiyaz Ahmed Hossainy , Florencia Lim , Michael Huy Ngo , O. Mikael Trollsas
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L31/16 , A61L2300/416 , C08L67/04 , C08L77/12
Abstract: The present invention provides a coating comprising a semi-crystalline polymer on an implantable device and methods of making and using the same.
Abstract translation: 本发明提供一种包含可植入装置上的半结晶聚合物的涂层及其制备和使用方法。
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Patent Agency Ranking
公开(公告)号：US09289318B2
公开(公告)日：2016-03-22
申请号：US14656553
申请日：2015-03-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Dariush Davalian , Michael Huy Ngo , Hao-Ming Hsiao , Boris Anukhin , Syed Hossainy , David Gale
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2210/0004 , A61F2230/0054 , A61F2250/0036 , A61L31/06 , A61L31/10 , A61L31/148 , C08L67/04
Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
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公开(公告)号：US20140277372A1
公开(公告)日：2014-09-18
申请号：US13840257
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Michael Huy Ngo , Samit Mustafa , Syed Hossainy , Mikael Trollsas
IPC: A61F2/82
CPC classification number: A61F2/82 , A61F2/915 , A61F2002/91575 , B29C49/08 , B29C55/26 , B29C2793/0009 , B29L2031/753 , B29L2031/7542 , Y10T29/49863
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a morphology resulting from a biaxially expanded tube arranged to provide a more balanced, or less anisotropic axial and radial mechanical properties. The scaffold has improved mechanical properties suited for use as a balloon expandable scaffold implanted in a peripheral vessel of the body.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架具有由双轴向膨胀的管形成的形状，其布置成提供更平衡或更不均匀的轴向和径向机械性能。 支架具有改善的机械性能，适合用作植入身体外周血管中的球囊扩张型支架。
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8.发明申请BIOABSORBABLE STENT WITH TIME DEPENDENT STRUCTURE AND PROPERTIES AND REGIO-SELECTIVE DEGRADATION 审中-公开具有时间依赖结构和特性的生物可降解性和选择性降解公开(公告)号：US20130245746A1
公开(公告)日：2013-09-19
申请号：US13866984
申请日：2013-04-19
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Mikael TROLLSAS , Dariush Davalian , Michael Huy Ngo , Hao-Ming Hsiao , Boris Anukhin , Syed F.A. Hossainy , David C. Gale
IPC: A61F2/89
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2210/0004 , A61F2230/0054 , A61F2250/0036 , A61L31/06 , A61L31/10 , A61L31/148 , C08L67/04
Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
Abstract translation: 公开了具有时间依赖性结构的生物可吸收聚合物支架，以及用生物可吸收聚合物支架治疗患病血管的特性和方法。 支架的结构和性质随时间而变化，并允许血管恢复到自然不稳定状态。 由于选择的结构元件的修饰，生物可吸收的支架以受控的方式失去机械完整性。
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公开(公告)号：US09956097B2
公开(公告)日：2018-05-01
申请号：US13842547
申请日：2013-03-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Chad J. Abunassar , Michael Huy Ngo , Erik David Eli , Santosh V. Prabhu , Mikael Trollsas , Richard Rapoza
CPC classification number: A61F2/915 , A61F2/958 , A61F2002/91575 , A61F2210/0004 , A61F2230/0054 , A61F2240/00 , A61F2240/008 , A61F2250/0071 , A61L31/06 , B29C55/24 , B29C55/26 , B29C69/001 , B29L2031/753 , Y10T29/49 , Y10T29/49927 , C08L67/04
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
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公开(公告)号：US09517150B2
公开(公告)日：2016-12-13
申请号：US13842432
申请日：2013-03-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Mikael Trollsas , Michael Huy Ngo , Erik David Eli
CPC classification number: A61F2/915 , A61F2/958 , A61F2002/91575 , A61F2210/0004 , A61F2230/0054 , A61F2240/00 , A61F2240/008 , A61F2250/0071 , A61L31/06 , B29C55/24 , B29C55/26 , B29C69/001 , B29L2031/753 , Y10T29/49 , Y10T29/49927 , C08L67/04
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架具有当植入在外周血管内时产生较低的晚期管腔损失并且也表现出高的轴向疲劳寿命的结构。 在优选实施例中，支架形成通过连杆互连的环形结构，其中环具有12个冠部，并且至多两个连接相邻环件的连杆。
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