公开(公告)号：US20160279095A1

公开(公告)日：2016-09-29

申请号：US15036001

申请日：2014-11-12

Applicant: ABBOTT LABORATORIES

Inventor： REMA VAZHAPPILLY ,  CHRON-SI LAI ,  MATTHEW KUCHAN

IPC: A61K31/355 ,  A61K31/047 ,  A61K31/202

CPC classification number: A61K31/355 ,  A23L33/10 ,  A23L33/12 ,  A23L33/15 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/047 ,  A61K31/20 ,  A61K31/202

Abstract: Disclosed herein are nutritional compositions for pregnant or lactating mothers, pre-term and term infants, toddlers and children which include natural vitamin E, a long chain polyunsaturated fatty acid (LC-PUFA) and a carotenoid such as lutein. Also disclosed are methods of administering these compositions for reducing or preventing the susceptibility of the fetal and newborn brain and lungs to hypoxia and the resulting disorders resulting therefrom including abnormal cognitive development, brain in jury and lung injury.

Abstract translation: 本文公开了含有天然维生素E，长链多不饱和脂肪酸（LC-PUFA）和类胡萝卜素如叶黄素的怀孕或哺乳期母亲，早产儿和术前婴儿，幼儿和儿童的营养组合物。 还公开了施用这些组合物以减少或预防胎儿和新生儿脑和肺对缺氧的易感性的方法以及由此引起的由此产生的病症，包括异常认知发育，陪审团和肺损伤中的脑。

公开(公告)号：US20170258759A1

公开(公告)日：2017-09-14

申请号：US15529305

申请日：2015-11-25

Applicant: ABBOTT LABORATORIES

Inventor： MATTHEW KUCHAN ,  CHRON-SI LAI ,  JACQUELINE BOFF

IPC: A61K31/355 ,  A23L33/12 ,  A61K31/047 ,  A23L33/00 ,  A61K31/015 ,  A23L33/155 ,  A23L33/15

CPC classification number: A61K31/355 ,  A23L33/12 ,  A23L33/15 ,  A23L33/155 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/01 ,  A61K31/015 ,  A61K31/047 ,  A61K31/065 ,  A61K31/122 ,  A61K2300/00

Abstract: Methods for improving the visual processing of a healthy infant by administering a composition comprising RRR-alpha-tocopherol and a carotenoid to the infant are disclosed. Methods for improving the visual acuity of a healthy infant by administering a composition comprising RRR-alpha-tocopherol and a carotenoid to the infant are also disclosed. Methods for improving the visual processing of a healthy infant by administering a composition comprising RRR-alpha-tocopherol to the infant are disclosed. Methods for improving the visual acuity of a healthy infant by administering a composition comprising RRR-alpha-tocopherol to the infant are also disclosed. Methods for improving the development of the visual processing, visual acuity, or both, of an infant by administering a composition comprising RRR-alpha-tocopherol to the infant are also disclosed.

公开(公告)号：US20180256536A1

公开(公告)日：2018-09-13

申请号：US15977390

申请日：2018-05-11

Applicant: ABBOTT LABORATORIES

Inventor： MATTHEW KUCHAN ,  CHRON-SI LAI ,  JACQUELINE BOFF

IPC: A61K31/355 ,  A61K31/047 ,  A61K31/015 ,  A23L33/00 ,  A23L33/15 ,  A23L33/12 ,  A23L33/155

CPC classification number: A61K31/355 ,  A23L33/12 ,  A23L33/15 ,  A23L33/155 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/01 ,  A61K31/015 ,  A61K31/047 ,  A61K31/065 ,  A61K31/122 ,  A61K2300/00

Abstract: Methods for improving the visual processing of a healthy infant by administering a composition comprising RRR-alpha-tocopherol to the infant are disclosed. Methods for improving the visual acuity of a healthy infant by administering a composition comprising RRR-alpha-tocopherol to the infant are also disclosed. Methods for improving the development of the visual processing, visual acuity, or both, of an infant by administering a composition comprising RRR-alpha-tocopherol to the infant are also disclosed.

公开(公告)号：US20180235930A1

公开(公告)日：2018-08-23

申请号：US15962545

申请日：2018-04-25

Applicant: ABBOTT LABORATORIES

Inventor： CHRON-SI LAI ,  MATTHEW KUCHAN

IPC: A61K31/355 ,  A23L33/00 ,  A61K31/202 ,  A23L33/12 ,  A61K9/00 ,  A23L33/15 ,  A61K47/22

Abstract: Disclosed are methods of using nutritional compositions generally, and infant formulas specifically, to improve cognitive, brain and/or central nervous system development in an individual. The nutritional compositions include a combination of RRR-alpha tocopherol acetate, non-RRR-alpha-tocopherol stereoisomers, fat, and protein. The amount of non-RRR alpha tocopherol stereoisomers in the nutritional compositions is limited.