公开(公告)号：US20160279095A1

公开(公告)日：2016-09-29

申请号：US15036001

申请日：2014-11-12

Applicant: ABBOTT LABORATORIES

Inventor： REMA VAZHAPPILLY ,  CHRON-SI LAI ,  MATTHEW KUCHAN

IPC: A61K31/355 ,  A61K31/047 ,  A61K31/202

CPC classification number: A61K31/355 ,  A23L33/10 ,  A23L33/12 ,  A23L33/15 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/047 ,  A61K31/20 ,  A61K31/202

Abstract: Disclosed herein are nutritional compositions for pregnant or lactating mothers, pre-term and term infants, toddlers and children which include natural vitamin E, a long chain polyunsaturated fatty acid (LC-PUFA) and a carotenoid such as lutein. Also disclosed are methods of administering these compositions for reducing or preventing the susceptibility of the fetal and newborn brain and lungs to hypoxia and the resulting disorders resulting therefrom including abnormal cognitive development, brain in jury and lung injury.

Abstract translation: 本文公开了含有天然维生素E，长链多不饱和脂肪酸（LC-PUFA）和类胡萝卜素如叶黄素的怀孕或哺乳期母亲，早产儿和术前婴儿，幼儿和儿童的营养组合物。 还公开了施用这些组合物以减少或预防胎儿和新生儿脑和肺对缺氧的易感性的方法以及由此引起的由此产生的病症，包括异常认知发育，陪审团和肺损伤中的脑。

公开(公告)号：US20160136192A1

公开(公告)日：2016-05-19

申请号：US14897462

申请日：2014-06-10

Applicant: ABBOTT LABORATORIES

Inventor： REMA VAZHAPPILLY ,  TAPAS DAS

IPC: A61K31/685 ,  A61K31/201 ,  A61K9/00 ,  A61K31/14

CPC classification number: A61K31/685 ,  A23L33/105 ,  A23L33/115 ,  A23L33/40 ,  A23V2002/00 ,  A61K9/0056 ,  A61K9/0095 ,  A61K31/14 ,  A61K31/201 ,  A61K31/661 ,  A61K2300/00 ,  A23V2200/322 ,  A23V2250/1846 ,  A23V2250/1852 ,  A23V2250/188

Abstract: Compositions including an effective amount of each of phosphatidyl serine, choline, and oleic acid, and methods for improving cognitive performance that include administering such compositions to a subject, are described herein. The compositions can be nutritional compositions such as bars or liquids suitable for oral administration. The combination of phosphatidyl serine, choline, and oleic acid provides synergistic or complimentary modes of action that improve the overall effect of these compounds.

Abstract translation: 本文描述了包含有效量的磷脂酰丝氨酸，胆碱和油酸的组合物，以及包括向受试者施用此类组合物的用于改善认知功能的方法。 组合物可以是营养组合物，例如适于口服给药的酒吧或液体。 磷脂酰丝氨酸，胆碱和油酸的组合提供增效或补充作用模式，改善这些化合物的总体效果。