公开(公告)号：US20200230191A1

公开(公告)日：2020-07-23

申请号：US16585984

申请日：2019-09-27

Applicant: ACADEMIA SINICA

Inventor： Lie-Fen SHYUR ,  Chih-Ting CHANG ,  Yuhsin CHEN

IPC: A61K36/534 ,  A61K31/015 ,  A61K31/122 ,  A61P35/00

Abstract: This disclosure is directed to essential oils, and methods of their use in treating skin conditions. The skin conditions include those involving HRASQ61L mutant keratinocyte activity, wherein the essential oil inhibits said activity to treat and/or prevent skin cancer. Particularly, the present invention denotes to and composition for inhibiting and prevent skin carcinogenesis or BRAF inhibitor, a type of anti-cancer drug induced cutaneous side effect.