Metal components with inert vapor phase coating on internal surfaces

    公开(公告)号:US10895009B2

    公开(公告)日:2021-01-19

    申请号:US16455354

    申请日:2019-06-27

    Abstract: The invention provides metal liquid chromatography components with uniformly coated internal surfaces and methods for achieving the same. The invention addresses the problem of corrosion or interference of metal components in the flow path for LC analyses in which the sample interacts with metal ions or surfaces. The invention also alleviates the difficulties in coating very long metal tubes and very small metal channels with an inert, continuous coating that adheres well to metal surfaces. The metal flow path is rendered inert by the coating, and thus compatible with bioanalytical separations, for example, by using a vapor phase deposition process to coat the inner surfaces with a coating that continuously covers all metal surfaces in the flow path.

    METAL COMPONENTS WITH INERT VAPOR PHASE COATING ON INTERNAL SURFACES

    公开(公告)号:US20190390329A1

    公开(公告)日:2019-12-26

    申请号:US16455354

    申请日:2019-06-27

    Abstract: The invention provides metal liquid chromatography components with uniformly coated internal surfaces and methods for achieving the same. The invention addresses the problem of corrosion or interference of metal components in the flow path for LC analyses in which the sample interacts with metal ions or surfaces. The invention also alleviates the difficulties in coating very long metal tubes and very small metal channels with an inert, continuous coating that adheres well to metal surfaces. The metal flow path is rendered inert by the coating, and thus compatible with bioanalytical separations, for example, by using a vapor phase deposition process to coat the inner surfaces with a coating that continuously covers all metal surfaces in the flow path.

    COMPONENTS WITH AN ATOMIC LAYER DEPOSITION COATING AND METHODS OF PRODUCING THE SAME
    9.
    发明申请
    COMPONENTS WITH AN ATOMIC LAYER DEPOSITION COATING AND METHODS OF PRODUCING THE SAME 审中-公开
    具有原子层沉积涂料的组分及其制备方法

    公开(公告)号:US20150122365A1

    公开(公告)日:2015-05-07

    申请号:US14597159

    申请日:2015-01-14

    Abstract: Liquid chromatography and gas chromatography components with a conformal protective coating on internal surfaces thereof and methods for producing the same are provided. The conformal protective coating is formed via an atomic layer deposition (ALD) process. The components and methods of the present disclosure find use in providing protective coatings for liquid chromatography and gas chromatography components that are compatible with bioanalytical separations and sensitive trace analyses.

    Abstract translation: 提供了在其内表面上具有保形涂层的液相色谱和气相色谱组分及其制备方法。 通过原子层沉积(ALD)工艺形成共形保护涂层。 本公开的组分和方法用于提供与生物分析分离和敏感痕量分析相容的液相色谱和气相色谱组分的保护性涂料。

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