Abstract:
In a communications network, it is necessary for client software applications to monitor detail records constructed from messages transmitted in a signalling network (100) associated with the communications network. Prior techniques for delivery of the detail records to the client software applications included separate generation of the detail records for each client software application resulting in duplication of effort in the collection and dissemination of the detail records as well as the prolific number of detail record generation tasks required. The present invention overcomes these disadvantages by having a single generator (200, 410) of detail records per site in the signalling network (100), the delivery of the detail records to the client software applications (400, 402, 710, 712, 718) involving a point-to-multipoint communication.
Abstract:
An apparatus for controlling the motion of a particle and a method for using the same are disclosed. The apparatus includes a channel containing liquid between first and second electrodes. The apparatus also includes an array of variable impedance elements, each variable impedance element connecting the first electrode to a corresponding location in the channel by a path having an average impedance that is continuously variable between first and second impedances when averaged over an update time interval. A controller sets the average impedance of each of the variable impedance elements such that a particle in the channel moves in a predetermined direction when voltage is applied between the first and second electrodes. At least one of the variable impedance elements has an average impedance that is intermediate between the first and second impedances.
Abstract:
An ATR scanner and method for calibrating the same are disclosed. The scanner includes an ATR objective having a reflecting face and an optical port adapted to receive a first light beam, and to focus the first light beam to a point, at a location on the reflecting face such that the first light beam is reflected by the reflecting face and no portion of the first light beam strikes the reflecting face at an angle greater than the critical angle. A detector measures an intensity of light reflected from the reflecting face. A controller controls the location of the focal point and determines an intensity of light that was incident on the reflecting face as a function of the position on the reflecting face and an intensity of light that was reflected from the reflecting face as a function of position on the reflecting face.
Abstract:
The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.
Abstract:
A sample separation apparatus includes a fluid drive arrangement having a first fluid drive unit and a second fluid drive unit for driving a mobile phase along a flow path to a sample separation unit, a sample accommodation volume configured to accommodate the fluidic sample and to be selectively fluidically coupleable with the flow path or fluidically decoupleable from the flow path, and a control unit configured to control respective operations of the fluid drive units, and to control a fluidically decoupling of the second fluid drive unit from the flow path in a decoupled operation mode of the sample separation apparatus. The control unit is further configured to control, in the decoupled operation mode, the decoupled second fluid drive unit for fluidically coupling to the sample accommodation volume, and intaking sample into the sample accommodation volume.
Abstract:
A method of controlling a sample separation apparatus, for separating a fluidic sample using a mobile phase provided from at least one mobile phase container, includes determining a weight and volume reduction behavior according to which weight and volume of mobile phase in a mobile phase container are reduced during conveying mobile phase from the mobile phase container in the sample separation apparatus, and determining a tare weight of the mobile phase container based on a gross weight information, a volume information, and the determined weight and volume reduction behavior. The gross weight information is indicative of an initial gross weight of the mobile phase container including its mobile phase, and the volume information is indicative of an initial mobile phase volume in the mobile phase container.
Abstract:
The present disclosure relates to a method of assembling long nucleic acids by enzymatically ligating oligonucleotide molecules hybridized to an indexed splint oligonucleotide molecules. Also disclosed are oligonucleotide structures comprising an indexed splint oligonucleotide useful in performing the disclosed method.
Abstract:
Methods of quantifying IgG antibodies containing high mannose N-glycans. Methods include immobilizing a protein capable of binding to IgG antibodies containing high mannose N-glycans to a substrate. Methods include adding a sample comprising IgG antibodies containing high mannose N-glycans to the immobilized protein to form a binding mixture. Methods further include adding a high mannose binder protein (HMB)-dye conjugate to the binding mixture such that the HMB-dye conjugate binds to high mannose N-glycans present in the sample. Methods include detecting the IgG antibodies containing high mannose N-glycans bound to the HMB-dye conjugate. Kits for the quantifying IgG antibodies containing high mannose N-glycans are also disclosed.
Abstract:
Novel tools and techniques are provided for implementing optimized scheduling of tasks involving equipment used by multiple individuals. In various embodiments, a computing system might receive, from a first user, a first request to use first equipment that is disposed in a work environment, the first request comprising information regarding a first task to be performed using the first equipment. The computing system might determine a core processing time during which the requested first equipment performs core processes involved with performing the first task, might determine a pre-processing time and a post-processing time involved with performance of the first task. The computing system might determine an estimated total processing time to complete the first task using the first equipment, based on the determined core processing time, pre-processing time, and post-processing time. The computing system might display the estimated total processing time to complete the first task using the first equipment.
Abstract:
Methods and systems for estimating gas supply pressure are described herein. The method can include measuring a runtime valve duty cycle for a valve of a gas chromatography system. The method can include estimating a runtime supply pressure from the runtime valve duty cycle and at least one of a runtime flow rate or downstream pressure based on one or more calibration valve duty cycles corresponding to one or more calibration supply pressures and one or more calibration flow rates. The method can include, responsive to determining the runtime supply pressure is greater than a threshold supply pressure value, generating a notification that the runtime supply pressure is greater than the threshold supply pressure value.