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公开(公告)号:US20240384213A1
公开(公告)日:2024-11-21
申请号:US18692853
申请日:2022-09-15
Applicant: AMOGREENTECH CO., LTD.
Inventor: Seon Ho JANG , Kyoung Ku HAN , In Yong SEO , Seoung Hoon LEE , Jae Kyung SONG , Song Hee KOO , Hee Sung PARK , Hyeong Tak NOH , Ji Young KIM , Su Yeon LEE , Seung Min CHO
Abstract: A bioreactor for suspension cells is provided. The bioreactor for suspension cells may comprise: a frame unit; a driving unit mounted on the frame unit, and a cell culture unit including a housing having an inner space filled with a medium containing suspension cells, and a plurality of supports disposed in multiple stages in the inner space to be spaced at intervals from each other, the cell culture unit having one end axially coupled to the driving unit.
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公开(公告)号:US20190338233A1
公开(公告)日:2019-11-07
申请号:US16309649
申请日:2017-06-13
Applicant: AMOGREENTECH CO., LTD.
Inventor: In Yong SEO , Seon Ho JANG , Chan KIM , Seoung Hoon LEE , Song Hee KOO
Abstract: Provided is yarn for a cell culture scaffold. The yarn for a cell culture scaffold according to an exemplary embodiment of the present invention includes slitting yarn produced by cutting a compressed nanofiber web to a predetermined width. Accordingly, by creating microenvironments suitable for migration, proliferation and differentiation of cells, cell viability may be enhanced and cells may be three-dimensionally proliferated. In addition, a scaffold according to the present invention has a mechanical strength sufficient for prevention of disruption of the scaffold which occurs during cell culture, such that cells may be stably proliferated. Further, the scaffold according to the present invention uses slitting yarn formed of the compressed nanofiber web, thereby having pores with various sizes, and therefore cell proliferation and cell viability may be enhanced by creation of an extracellular matrix-like environment.
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公开(公告)号:US20240052281A1
公开(公告)日:2024-02-15
申请号:US18259571
申请日:2021-12-29
Applicant: AMOGREENTECH CO., LTD.
Inventor: Seon Ho JANG , Seoung Hoon LEE , In Yong SEO , Chan KIM , Kyoung Ku HAN , Jae Yun KIM
Abstract: An air bubble removal device for removing air bubbles from a medium including a housing including an inner space for storing a predetermined amount of the medium, an introduction port through which the medium is introduced from the outside into the inner space, and a discharge port through which the medium in a state in which air bubbles have been removed is discharged from the inner space to the outside; and a support part coupled to the housing so as to maintain the housing in a state spaced a predetermined height from a bottom surface.
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公开(公告)号:US20220002651A1
公开(公告)日:2022-01-06
申请号:US17293993
申请日:2019-11-14
Applicant: AMOGREENTECH CO., LTD.
Inventor: Seon Ho JANG , Hee Sung PARK , Kyung Gu HAN , Dong Sik SEO , Song Hee KOO , Ji Young KIM , Hyo Jung LEE , Su Yeon LEE , In Yong SEO , Seoung Hoon LEE , Chan KIM
IPC: C12M1/12
Abstract: Provided is a cell culture sheet for a large-capacity incubator. A cell culture sheet according to one embodiment of the present invention is a cell culture sheet provided in a large-capacity incubator having a plurality of sheets disposed to be spaced apart at predetermined intervals therein, wherein the cell culture sheet has an area of 100 cm2 or more and a bending depth of 0.5 cm or less. As such, even when the culture sheets are closely placed in a limited volume of space, there is little sagging or shape deformation in a specific direction to prevent the occurrence of contact with adjacent culture sheets, thereby preventing a decrease in cell culture volume due to a dead space. Furthermore, since the flow of a cell culture fluid due to the occurrence of contact can be minimized or prevented, a large capacity of cells can be stably and smoothly cultivated such that the cell culture sheet is very suitable for a large-capacity incubator and can be widely applied to the cell culture industry.
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公开(公告)号:US20250136909A1
公开(公告)日:2025-05-01
申请号:US18692842
申请日:2022-09-15
Applicant: AMOGREENTECH CO., LTD.
Inventor: Seon Ho JANG , Kyoung Ku HAN , In Yong SEO , Seoung Hoon LEE , Jae Kyung SONG , Song Hee KOO , Hee Sung PARK , Hyeong Tak NOH , Ji Young KIM , Su Yeon LEE , Seung Min CHO
Abstract: A portable bioreactor is provided. The portable bioreactor may comprise: a frame unit; a cell culture unit which has one side mounted to the frame unit and in which a plurality of supports for cell culture are arranged, the cell culture unit being provided with an inlet, through which a medium supplied from the outside flows in, and an outlet, through which the medium inside the cell culture unit is discharged to the outside, a medium adjustment unit installed in the frame unit and storing therein a certain amount of medium for the cell culture; a circulation pump installed and fixed to the frame unit to circulate the medium stored in the medium adjustment unit; and a gas supply unit for supplying gas to the medium adjustment unit to maintain the medium stored in the medium adjustment unit at a constant pH.
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公开(公告)号:US20250066962A1
公开(公告)日:2025-02-27
申请号:US18723318
申请日:2022-12-22
Applicant: AMOGREENTECH CO., LTD.
Inventor: Chan KIM , Hyo Jung LEE , Seoung Hoon LEE , Kang Sik SHIN , Yun Mi SO
Abstract: A thermally adhesive fiber web implemented by including the steps of: (1) preparing respectively a first spinning solution in which a support component and a second spinning solution in which a thermally adhesive component; (2) performing electrospinning such that the first spinning solution is discharged to a portion of the end surface of a discharge port and the second spinning solution is discharged to the remaining portion, thereby accumulating side-by-side type thermally adhesive composite fibers having a diameter of less than 1 μm; and (3) applying heat to the accumulated side-by-side type thermally adhesive composite fibers. The thermally adhesive fiber web enables easy interfacial bonding to a heterogeneous material with a different material and structural specification and prevents pores formed in an initial stage from being closed during thermal bonding.
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公开(公告)号:US20240409865A1
公开(公告)日:2024-12-12
申请号:US18698784
申请日:2022-09-15
Applicant: AMOGREENTECH CO., LTD.
Inventor: Seon Ho JANG , Kyoung Ku HAN , In Yong SEO , Seoung Hoon LEE , Song Hee KOO , Hyeong Tak NOH , Ji Young KIM , Su Yeon LEE
Abstract: A bioreactor for suspended cells is provided. The bioreactor for suspended cells comprises: a housing which is formed in the shape of a container having a culture space with a predetermined volume, and which comprises pots for seeding; a support assembly comprising a plurality of supports arranged at intervals in multiple stages in one direction of the housing; at least one gas inlet penetrating the housing by a predetermined area; and a porous member for covering the gas inlet, wherein the culture space comprises a medium storage space filled with a predetermined amount of a medium so that all the plurality of supports are submerged therein, and the medium storage space can comprise a plurality of cell growth spaces divided through the plurality of supports arranged at intervals in multiple stages.
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公开(公告)号:US20230201405A1
公开(公告)日:2023-06-29
申请号:US17999446
申请日:2021-05-24
Applicant: AMOGREENTECH CO., LTD.
Inventor: Seoung Hoon LEE , Seon Ho JANG , In Yong SEO , Chan KIM , Dong Sik SEO
CPC classification number: A61L9/16 , C07K14/001 , C07K7/04 , C09D189/00 , F24F8/10 , B01D39/1607 , C07K2319/00 , B01D2239/0492 , B01D2239/0442
Abstract: Provided is an antiviral filter medium. An antiviral filter medium according to one embodiment of the present invention includes a first member provided with an antiviral coating layer formed of fibers and including, on part or all of the outer surface of the fibers, an antiviral fusion protein in which an antiviral motif is bound to an adhesive protein. Accordingly, the antiviral filter medium exhibits antiviral properties, is excellent in filtration efficiency and ventilation amount (or flow rate), and has low pressure loss. In addition, the antiviral filter medium is characterized in that the coating layer exhibiting antiviral properties retains adhesiveness for a long period of time after being attached to the surface. Moreover, the antiviral filter medium can retain antiviral activity for a long time without loss of the antiviral activity due to external conditions during production, storage, and use.
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公开(公告)号:US20230080853A1
公开(公告)日:2023-03-16
申请号:US17904339
申请日:2021-02-17
Applicant: AMOGREENTECH CO., LTD.
Inventor: SeonHo JANG , Hee Sung PARK , Sung Il KIM , Seam MUN , Song Hee KOO , Su Yeon LEE , Ji Young KIM , In Yong SEO , Seoung Hoon LEE , Chan KIM
Abstract: A method for manufacturing a fiber assembly for providing a binding surface to a bio-substance is provided. A fiber assembly for providing a binding surface to a bio-substance according to an embodiment of the present invention is manufactured by a method comprising the steps of: (1) preparing a fiber assembly in which a plurality of fibers is accumulated; and (2) performing modification to provide the fiber surface with a carboxyl group reactive to an amine group present in a bio-substance. According to the method, a bio-substance can be easily introduced at a high content into the fiber assembly. In addition, bio-substances that are conjugated therebetween and adsorbed through physical adsorption, etc. are remarkably reduced in the introduction procedure of bio-substances, whereby bio-substances can be availed with high precision and reliability in applications employing bio-substances. Furthermore, applications employing bio-substances can undergo minimal property variations attributed to the bio-substances as detachment of the bio-substances is minimized or prevented. Accordingly, the bio-substances fixed on the surface of the fiber assembly according to the present invention can find a broad spectrum of applications in various fields including the material engineering, bio engineering, medical fields, and so on.
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公开(公告)号:US20220389362A1
公开(公告)日:2022-12-08
申请号:US17754995
申请日:2020-10-12
Applicant: AMOGREENTECH CO., LTD.
Inventor: Hee Sung PARK , In Yong SEO , Seoung Hoon LEE , Seon Ho JANG , Su Yeon LEE , Ji Young KIM , Hyo Jung LEE
Abstract: A cell culture apparatus is provided. A cell culture apparatus according to one exemplary embodiment of the present invention comprises: a cell culture part comprising an accommodation space in which a plurality of supports for cell culture are disposed; a medium supply part for storing a predetermined amount of medium to be supplied to the cell culture part, and maintaining a predetermined carbon dioxide concentration of the medium stored therein by using carbon dioxide introduced from the outside through a gas supply port; and a pump, which interconnects the cell culture part and the medium supply part so as to circulate, in the cell culture part, a medium stored in the medium supply part.
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