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    CELL CULTURE SHEET ASSEMBLY FOR LARGE-CAPACITY INCUBATOR, AND LARGE-CAPACITY INCUBATOR COMPRISING SAME
    1.
    发明申请
    CELL CULTURE SHEET ASSEMBLY FOR LARGE-CAPACITY INCUBATOR, AND LARGE-CAPACITY INCUBATOR COMPRISING SAME 有权

    公开(公告)号：US20220002651A1

    公开(公告)日：2022-01-06

    申请号：US17293993

    申请日：2019-11-14

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： Seon Ho JANG ,  Hee Sung PARK ,  Kyung Gu HAN ,  Dong Sik SEO ,  Song Hee KOO ,  Ji Young KIM ,  Hyo Jung LEE ,  Su Yeon LEE ,  In Yong SEO ,  Seoung Hoon LEE ,  Chan KIM

    IPC: C12M1/12

    Abstract: Provided is a cell culture sheet for a large-capacity incubator. A cell culture sheet according to one embodiment of the present invention is a cell culture sheet provided in a large-capacity incubator having a plurality of sheets disposed to be spaced apart at predetermined intervals therein, wherein the cell culture sheet has an area of 100 cm2 or more and a bending depth of 0.5 cm or less. As such, even when the culture sheets are closely placed in a limited volume of space, there is little sagging or shape deformation in a specific direction to prevent the occurrence of contact with adjacent culture sheets, thereby preventing a decrease in cell culture volume due to a dead space. Furthermore, since the flow of a cell culture fluid due to the occurrence of contact can be minimized or prevented, a large capacity of cells can be stably and smoothly cultivated such that the cell culture sheet is very suitable for a large-capacity incubator and can be widely applied to the cell culture industry.

    METHOD FOR MANUFACTURING FIBER ASSEMBLY FOR PROVIDING BINDING SURFACE TO BIOSUBSTANCE AND FIBER ASSEMBLY, MANUFACTURED THEREBY, FOR PROVIDING BINDING SURFACE TO BIOSUBSTANCE
    2.
    发明申请
    METHOD FOR MANUFACTURING FIBER ASSEMBLY FOR PROVIDING BINDING SURFACE TO BIOSUBSTANCE AND FIBER ASSEMBLY, MANUFACTURED THEREBY, FOR PROVIDING BINDING SURFACE TO BIOSUBSTANCE 有权

    公开(公告)号：US20230080853A1

    公开(公告)日：2023-03-16

    申请号：US17904339

    申请日：2021-02-17

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： SeonHo JANG ,  Hee Sung PARK ,  Sung Il KIM ,  Seam MUN ,  Song Hee KOO ,  Su Yeon LEE ,  Ji Young KIM ,  In Yong SEO ,  Seoung Hoon LEE ,  Chan KIM

    IPC: C07K17/08 ,  C08L79/02

    Abstract: A method for manufacturing a fiber assembly for providing a binding surface to a bio-substance is provided. A fiber assembly for providing a binding surface to a bio-substance according to an embodiment of the present invention is manufactured by a method comprising the steps of: (1) preparing a fiber assembly in which a plurality of fibers is accumulated; and (2) performing modification to provide the fiber surface with a carboxyl group reactive to an amine group present in a bio-substance. According to the method, a bio-substance can be easily introduced at a high content into the fiber assembly. In addition, bio-substances that are conjugated therebetween and adsorbed through physical adsorption, etc. are remarkably reduced in the introduction procedure of bio-substances, whereby bio-substances can be availed with high precision and reliability in applications employing bio-substances. Furthermore, applications employing bio-substances can undergo minimal property variations attributed to the bio-substances as detachment of the bio-substances is minimized or prevented. Accordingly, the bio-substances fixed on the surface of the fiber assembly according to the present invention can find a broad spectrum of applications in various fields including the material engineering, bio engineering, medical fields, and so on.

    ANTIMICROBIAL DRESSING
    4.
    发明申请
    ANTIMICROBIAL DRESSING 审中-公开

    公开(公告)号：US20190117464A1

    公开(公告)日：2019-04-25

    申请号：US15559667

    申请日：2016-05-19

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： In Yong SEO ,  Seung Hoon LEE ,  Song Hee KOO ,  Ji Hyun LEE

    IPC: A61F13/00 ,  A61L15/42 ,  A61L15/44 ,  A61L15/26 ,  A61L15/28 ,  A61L15/24

    Abstract: Provided is an antimicrobial dressing, which includes: a first cover member having a plurality of pores formed therein and contacting a wound; an antimicrobial membrane that is made by accumulating nanofibers containing a water-soluble polymer that is dissolved in an exudate secreted from the wound, a synthetic polymer, and an antimicrobial substance released due to dissolution of the water-soluble polymer, the antimicrobial membrane being laminated on the first cover member and having a plurality of pores formed therein; and a second cover member laminated on the antimicrobial membrane and having a plurality of pores formed therein and exposed to an external air.

    EXOSOME EXTRACTION SYSTEM
    5.
    发明申请
    EXOSOME EXTRACTION SYSTEM 有权

    公开(公告)号：US20240408520A1

    公开(公告)日：2024-12-12

    申请号：US18701289

    申请日：2022-10-14

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： Seon Ho JANG ,  Song Hee KOO

    IPC: B01D35/02 ,  B01D15/34 ,  B01D29/56 ,  C12M1/00 ,  C12M1/26 ,  C12M1/33

    Abstract: An exosome extraction system is provided. The exosome extraction system according to one embodiment of the present invention may include: a raw material supply unit for supplying a cell fluid containing cells; a cell disruptor which disrupts the cells through physical impact to convert the cell fluid supplied from the raw material supply unit, into a cell lysate including microvesicles, exosomes, and proteins; a filter unit for separating the exosomes from the cell lysate supplied from the cell disruptor; and a recovery unit for recovering the exosomes separated from the filter unit.

    YARN FOR CELL CULTURE SCAFFOLD AND FABRIC COMPRISING THE SAME
    7.
    发明申请
    YARN FOR CELL CULTURE SCAFFOLD AND FABRIC COMPRISING THE SAME 审中-公开

    公开(公告)号：US20190338233A1

    公开(公告)日：2019-11-07

    申请号：US16309649

    申请日：2017-06-13

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： In Yong SEO ,  Seon Ho JANG ,  Chan KIM ,  Seoung Hoon LEE ,  Song Hee KOO

    IPC: C12M1/12 ,  C12N5/00 ,  A61L27/54 ,  A61L27/16 ,  A61L27/38 ,  D02G3/44 ,  D02J3/02

    Abstract: Provided is yarn for a cell culture scaffold. The yarn for a cell culture scaffold according to an exemplary embodiment of the present invention includes slitting yarn produced by cutting a compressed nanofiber web to a predetermined width. Accordingly, by creating microenvironments suitable for migration, proliferation and differentiation of cells, cell viability may be enhanced and cells may be three-dimensionally proliferated. In addition, a scaffold according to the present invention has a mechanical strength sufficient for prevention of disruption of the scaffold which occurs during cell culture, such that cells may be stably proliferated. Further, the scaffold according to the present invention uses slitting yarn formed of the compressed nanofiber web, thereby having pores with various sizes, and therefore cell proliferation and cell viability may be enhanced by creation of an extracellular matrix-like environment.

    PORTABLE BIOREACTOR
    8.
    发明申请
    PORTABLE BIOREACTOR 有权

    公开(公告)号：US20250136909A1

    公开(公告)日：2025-05-01

    申请号：US18692842

    申请日：2022-09-15

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： Seon Ho JANG ,  Kyoung Ku HAN ,  In Yong SEO ,  Seoung Hoon LEE ,  Jae Kyung SONG ,  Song Hee KOO ,  Hee Sung PARK ,  Hyeong Tak NOH ,  Ji Young KIM ,  Su Yeon LEE ,  Seung Min CHO

    IPC: C12M3/00 ,  C12M1/00 ,  C12M1/12 ,  C12M1/34

    Abstract: A portable bioreactor is provided. The portable bioreactor may comprise: a frame unit; a cell culture unit which has one side mounted to the frame unit and in which a plurality of supports for cell culture are arranged, the cell culture unit being provided with an inlet, through which a medium supplied from the outside flows in, and an outlet, through which the medium inside the cell culture unit is discharged to the outside, a medium adjustment unit installed in the frame unit and storing therein a certain amount of medium for the cell culture; a circulation pump installed and fixed to the frame unit to circulate the medium stored in the medium adjustment unit; and a gas supply unit for supplying gas to the medium adjustment unit to maintain the medium stored in the medium adjustment unit at a constant pH.

    BIOREACTOR FOR SUSPENDED CELLS
    9.
    发明申请
    BIOREACTOR FOR SUSPENDED CELLS 有权

    公开(公告)号：US20240409865A1

    公开(公告)日：2024-12-12

    申请号：US18698784

    申请日：2022-09-15

    Applicant: AMOGREENTECH CO., LTD.

    Inventor： Seon Ho JANG ,  Kyoung Ku HAN ,  In Yong SEO ,  Seoung Hoon LEE ,  Song Hee KOO ,  Hyeong Tak NOH ,  Ji Young KIM ,  Su Yeon LEE

    IPC: C12M1/00 ,  C12M1/107 ,  C12M1/12 ,  C12M3/00

    Abstract: A bioreactor for suspended cells is provided. The bioreactor for suspended cells comprises: a housing which is formed in the shape of a container having a culture space with a predetermined volume, and which comprises pots for seeding; a support assembly comprising a plurality of supports arranged at intervals in multiple stages in one direction of the housing; at least one gas inlet penetrating the housing by a predetermined area; and a porous member for covering the gas inlet, wherein the culture space comprises a medium storage space filled with a predetermined amount of a medium so that all the plurality of supports are submerged therein, and the medium storage space can comprise a plurality of cell growth spaces divided through the plurality of supports arranged at intervals in multiple stages.

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