公开(公告)号：US20130310617A1

公开(公告)日：2013-11-21

申请号：US13951137

申请日：2013-07-25

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C5/03

CPC classification number: C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C07C2523/44 ,  C07C2523/755 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10G2300/1011 ,  C10G2300/1055 ,  C10G2300/201 ,  C10G2300/4081 ,  C10G2300/802 ,  C10G2400/22 ,  C10L1/04 ,  C10L1/1608 ,  C10L1/1832 ,  Y02P30/20 ,  C07C9/16

Abstract: Processes and systems for stabilization and subsequent hydrogenation of an immiscible olefin are described. In certain embodiments, the hydrogenation is conducted in a fixed bed reactor in presence of a hydrogenation catalyst.

Abstract translation: 描述了不混溶烯烃的稳定化和随后氢化的方法和系统。 在某些实施方案中，氢化在氢化催化剂存在下在固定床反应器中进行。

公开(公告)号：US10183901B2

公开(公告)日：2019-01-22

申请号：US15458907

申请日：2017-03-14

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C1/00 ,  C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10L1/04 ,  C10L1/16 ,  C10L1/183

Abstract: Methods and compositions for stabilization and subsequent hydrogenation of a microbial-derived immiscible olefin are described. The methods comprise separating immiscible olefin from a mixture comprising an aqueous solution, microbial cells and immiscible olefin thereby forming a crude olefin composition; purifying the crude olefin composition thereby forming a purified olefin composition; and adding a phenolic antioxidant to the purified olefin composition wherein the phenolic antioxidant is a phenol derivative containing an unfused phenyl ring with one or more hydroxyl substituents. The methods further comprise reacting the purified olefin composition with hydrogen in the presence of a hydrogen catalyst such that hydrogen saturates at least one double bond in the olefin. Hydrogenated compositions produced by the methods are further provided.

公开(公告)号：US20170283346A1

公开(公告)日：2017-10-05

申请号：US15458907

申请日：2017-03-14

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C5/03 ,  C10G45/00 ,  C10L1/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C07C11/21 ,  C10G53/04

CPC classification number: C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C07C2523/44 ,  C07C2523/755 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10G2300/1011 ,  C10G2300/1055 ,  C10G2300/201 ,  C10G2300/4081 ,  C10G2300/802 ,  C10G2400/22 ,  C10L1/04 ,  C10L1/1608 ,  C10L1/1832 ,  Y02P30/20 ,  C07C9/16

Abstract: Methods and compositions for stabilization and subsequent hydrogenation of a microbial-derived immiscible olefin are described. The methods comprise separating immiscible olefin from a mixture comprising an aqueous solution, microbial cells and immiscible olefin thereby forming a crude olefin composition; purifying the crude olefin composition thereby forming a purified olefin composition; and adding a phenolic antioxidant to the purified olefin composition wherein the phenolic antioxidant is a phenol derivative containing an unfused phenyl ring with one or more hydroxyl substituents. The methods further comprise reacting the purified olefin composition with hydrogen in the presence of a hydrogen catalyst such that hydrogen saturates at least one double bond in the olefin. Hydrogenated compositions produced by the methods are further provided.

公开(公告)号：US20130310615A1

公开(公告)日：2013-11-21

申请号：US13951160

申请日：2013-07-25

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C5/03

CPC classification number: C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C07C2523/44 ,  C07C2523/755 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10G2300/1011 ,  C10G2300/1055 ,  C10G2300/201 ,  C10G2300/4081 ,  C10G2300/802 ,  C10G2400/22 ,  C10L1/04 ,  C10L1/1608 ,  C10L1/1832 ,  Y02P30/20 ,  C07C9/16

Abstract: Processes and systems for stabilization and subsequent hydrogenation of an immiscible olefin are described. In certain embodiments, the hydrogenation is conducted in a fixed bed reactor in presence of a hydrogenation catalyst.

公开(公告)号：US10894754B2

公开(公告)日：2021-01-19

申请号：US16228567

申请日：2018-12-20

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10L1/04 ,  C10L1/16 ,  C10L1/183

Abstract: Processes and systems for stabilization and subsequent hydrogenation of an immiscible olefin are described. In certain embodiments, the hydrogenation is conducted in a fixed bed reactor in presence of a hydrogenation catalyst.

公开(公告)号：US20190119184A1

公开(公告)日：2019-04-25

申请号：US16228567

申请日：2018-12-20

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C5/03 ,  C10G67/06 ,  C10L1/04 ,  C07C7/20 ,  C07C11/21 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04

Abstract: Processes and systems for stabilization and subsequent hydrogenation of an immiscible olefin are described. In certain embodiments, the hydrogenation is conducted in a fixed bed reactor in presence of a hydrogenation catalyst.

公开(公告)号：US09611189B2

公开(公告)日：2017-04-04

申请号：US13951137

申请日：2013-07-25

Applicant: AMYRIS, INC.

Inventor： Nicholas L. Ohler ,  Roberto Vazquez

IPC: C07C1/00 ,  C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10L1/04 ,  C10L1/16 ,  C10L1/183

CPC classification number: C07C5/03 ,  C07C7/20 ,  C07C11/21 ,  C07C2523/44 ,  C07C2523/755 ,  C10G45/00 ,  C10G53/04 ,  C10G53/08 ,  C10G67/04 ,  C10G67/06 ,  C10G2300/1011 ,  C10G2300/1055 ,  C10G2300/201 ,  C10G2300/4081 ,  C10G2300/802 ,  C10G2400/22 ,  C10L1/04 ,  C10L1/1608 ,  C10L1/1832 ,  Y02P30/20 ,  C07C9/16

Abstract: Methods and compositions for stabilization and subsequent hydrogenation of a microbial-derived immiscible olefin are described. The methods comprise providing a feed stream to the inlet of a reactor, wherein the feed stream comprises a microbial-derived immiscible olefin composition stabilized with a phenolic antioxidant which is a phenol derivative containing an unfused phenyl ring with one or more hydroxyl substituents. The methods further comprise contacting the feed stream with hydrogen in the presence of a hydrogenation catalyst at a temperature of about 20° C. or greater, and generating a product stream comprising a hydrogenated immiscible olefin composition. The microbial-derived immiscible olefin composition stabilized with the phenolic antioxidant remains stable over time, and its hydrogenation reaction time and process are improved.