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公开(公告)号：US10395368B2
公开(公告)日：2019-08-27
申请号：US15378495
申请日：2016-12-14
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Marilou L. Coleman , Walter G. Stonas , Willie J. Cowart , Wenjing Li , Ema C. Olah
Abstract: The present disclosure includes methods of assessing a histologically stained specimen based on a determined color signature of a region of interest of the specimen. Such assessments may be performed for a variety of purposes including but not limited to assessing the quality of the histological stain, as part of identifying one or more biologically relevant features of the image, as part of differentiating one feature of the image from other features of the image, identifying an anomalous area of the stained specimen, classifying cells of the specimen, etc. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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公开(公告)号：US20210123839A1
公开(公告)日：2021-04-29
申请号：US17095193
申请日：2020-11-11
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Mahmoud Janbakhsh , Ema C. Olah , Robert Langsner
Abstract: The present disclosure provides methods for the automated control of aspects of slide preparation in an automated slide preparation instrument. Aspects of the methods include automated assessments of reagent amounts, quality and performance as well as automated adjustments of reagents based on such assessments, including the adjustment of reagent amounts, e.g., as present in reagent baths, the adjustment of reagent compositions and the replacement of reagents. Devices and systems useful in performing the described methods are also provided herein.
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公开(公告)号：US20180143111A1
公开(公告)日：2018-05-24
申请号：US15792460
申请日：2017-10-24
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Mahmoud Janbakhsh , Ema C. Olah , Robert Langsner
CPC classification number: G01N1/30 , G01F23/68 , G01F23/706 , G01F25/0061 , G01N1/312 , G01N35/00663 , G01N2001/302 , G01N2001/315 , G01N2035/00673 , G06K9/00147 , G06K9/6202 , G06K9/6212 , G06K2209/05 , G06T7/0014 , G06T7/90 , G06T2207/10024 , G06T2207/10056 , G06T2207/30024
Abstract: The present disclosure provides methods for the automated control of aspects of slide preparation in an automated slide preparation instrument. Aspects of the methods include automated assessments of reagent amounts, quality and performance as well as automated adjustments of reagents based on such assessments, including the adjustment of reagent amounts, e.g., as present in reagent baths, the adjustment of reagent compositions and the replacement of reagents. Devices and systems useful in performing the described methods are also provided herein.
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Patent Agency Ranking
公开(公告)号：US11158049B2
公开(公告)日：2021-10-26
申请号：US16511479
申请日：2019-07-15
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Marilou L. Coleman , Walter G. Stonas , Willie J. Cowart , Wenjing Li , Ema C. Olah
Abstract: The present disclosure includes methods of assessing a histologically stained specimen based on a determined color signature of a region of interest of the specimen. Such assessments may be performed for a variety of purposes including but not limited to assessing the quality of the histological stain, as part of identifying one or more biologically relevant features of the image, as part of differentiating one feature of the image from other features of the image, identifying an anomalous area of the stained specimen, classifying cells of the specimen, etc. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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公开(公告)号：US11105736B2
公开(公告)日：2021-08-31
申请号：US16356654
申请日：2019-03-18
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Ema C. Olah
IPC: G01N21/31 , G01J1/00 , G01N1/30 , G01N33/483 , G01J3/10
Abstract: The instant disclosure provides spectrophotometric methods for assessing histological stains used in a histology analyzer. The methods find use in various assessments including determinations of the identity of a histological stain, determinations of the quality of a histological stain, etc. Also included are devices and systems for practicing the described methods. The instant disclosure also provides computer readable media containing libraries of reference spectrophotometric characteristics of histological stains useful in assessing a histological stain used in a histology analyzer. Also provided is computer readable media containing instructions that cause a computing device to perform steps for making an assessment of a histological stain.
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公开(公告)号：US20200080934A1
公开(公告)日：2020-03-12
申请号：US16356654
申请日：2019-03-18
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Ema C. Olah
IPC: G01N21/31 , G01N33/483 , G01N1/30 , G01J1/00
Abstract: The instant disclosure provides spectrophotometric methods for assessing histological stains used in a histology analyzer. The methods find use in various assessments including determinations of the identity of a histological stain, determinations of the quality of a histological stain, etc. Also included are devices and systems for practicing the described methods. The instant disclosure also provides computer readable media containing libraries of reference spectrophotometric characteristics of histological stains useful in assessing a histological stain used in a histology analyzer. Also provided is computer readable media containing instructions that cause a computing device to perform steps for making an assessment of a histological stain.
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公开(公告)号：US20200005459A1
公开(公告)日：2020-01-02
申请号：US16511479
申请日：2019-07-15
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Marilou L. Coleman , Walter G. Stonas , Willie J. Cowart , Wenjing Li , Ema C. Olah
Abstract: The present disclosure includes methods of assessing a histologically stained specimen based on a determined color signature of a region of interest of the specimen. Such assessments may be performed for a variety of purposes including but not limited to assessing the quality of the histological stain, as part of identifying one or more biologically relevant features of the image, as part of differentiating one feature of the image from other features of the image, identifying an anomalous area of the stained specimen, classifying cells of the specimen, etc. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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公开(公告)号：US10288557B2
公开(公告)日：2019-05-14
申请号：US15379119
申请日：2016-12-14
Applicant: Abbott Laboratories
Inventor： Svitlana Y. Berezhna , Rene Nieves Alicea , Ema C. Olah
Abstract: The instant disclosure provides spectrophotometric methods for assessing histological stains used in a histology analyzer. The methods find use in various assessments including determinations of the identity of a histological stain, determinations of the quality of a histological stain, etc. Also included are devices and systems for practicing the described methods. The instant disclosure also provides computer readable media containing libraries of reference spectrophotometric characteristics of histological stains useful in assessing a histological stain used in a histology analyzer. Also provided is computer readable media containing instructions that cause a computing device to perform steps for making an assessment of a histological stain.
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