公开(公告)号：US11946913B2

公开(公告)日：2024-04-02

申请号：US17730553

申请日：2022-04-27

Applicant: Agilent Technologies, Inc.

Inventor： Thomas Ortmann ,  Martin Seifried ,  Sam Wouters ,  Irina Spuling

IPC: G01N30/20 ,  G01N30/14 ,  G01N30/32 ,  G01N30/02

CPC classification number: G01N30/20 ,  G01N30/14 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/326

Abstract: An injector is configured for injecting a fluidic sample from an injector path into a mobile phase in a separation path between a fluid drive and a sample separation unit of a sample separation device. The injector includes a control unit configured for generating a first overpressure in a blocked first partial path of the injector path by a first pressure source, for generating a second overpressure in a blocked second partial path of the injector path by a second pressure source, for subsequently fluidically coupling the first partial path with the second partial path for generating an expansion stroke for releasing a gas bubble in the injector path, and for rinsing the released gas bubble from the injector path.

公开(公告)号：US20240201143A1

公开(公告)日：2024-06-20

申请号：US18430447

申请日：2024-02-01

Applicant: Agilent Technologies, Inc.

Inventor： Thomas Ortmann ,  Martin Seifried ,  Sam Wouters ,  Irina Spuling

IPC: G01N30/20 ,  G01N30/02 ,  G01N30/14 ,  G01N30/32

CPC classification number: G01N30/20 ,  G01N30/14 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/326

Abstract: A sample separation device includes a separation path and a control unit. The separation path is between a fluid drive and a sample separation unit, and is configured to inject a fluidic sample in an injector path into a mobile phase in the separation path driven by the fluid drive to the sample separation unit for chromatographically separating the fluidic sample. The control unit is configured to control blocking the injector path or at least a partial path thereof, generating an overpressure in the blocked injector path or the partial path thereof by a pressure source, and subsequently fluidically coupling the injector path or the partial path thereof to a region of lower pressure than the overpressure to generate an expansion stroke for releasing unwanted components from the injector path.

公开(公告)号：US20220341897A1

公开(公告)日：2022-10-27

申请号：US17730553

申请日：2022-04-27

Applicant: Agilent Technologies, Inc.

Inventor： Thomas Ortmann ,  Martin Seifried ,  Sam Wouters ,  Irina Spuling

IPC: G01N30/20 ,  G01N30/14 ,  G01N30/32

Abstract: An injector is configured for injecting a fluidic sample from an injector path into a mobile phase in a separation path between a fluid drive and a sample separation unit of a sample separation device. The injector includes a control unit configured for generating a first overpressure in a blocked first partial path of the injector path by a first pressure source, for generating a second overpressure in a blocked second partial path of the injector path by a second pressure source, for subsequently fluidically coupling the first partial path with the second partial path for generating an expansion stroke for releasing a gas bubble in the injector path, and for rinsing the released gas bubble from the injector path.