公开(公告)号：US11815488B2

公开(公告)日：2023-11-14

申请号：US16960307

申请日：2019-01-11

Applicant: Agilent Technologies, Inc.

Inventor： Michael J. Kimzey ,  Fielito U. Limjap ,  Francis T. Haxo ,  Sergey Vlasenko

IPC: G01N27/447 ,  C12N15/10

CPC classification number: G01N27/44747 ,  C12N15/101 ,  G01N27/44791

Abstract: The present disclosure provides methods of improving the resolution of analytes by in electrophoretic separations using a gel by incorporating into the gel an effective amount of one or more tri- or tetra-hydroxyl quaternary ammonium compounds, or a mixture of such compounds.

公开(公告)号：US11376200B2

公开(公告)日：2022-07-05

申请号：US16965915

申请日：2019-01-31

Applicant: Agilent Technologies, Inc.

Inventor： Sergey Vlasenko ,  Francis T. Haxo ,  Andres Guerrero Navarro

IPC: A61K8/36 ,  A61K31/196 ,  G01N33/50 ,  G01N21/64 ,  C07C63/06 ,  C08B37/00

Abstract: The present disclosure provides methods for using anthranilic acid (2-AA) blocked by tertbutyloxycarbonyl (Boc) groups in protocols for labeling glycans for analysis, and kits providing 2-AA-Boc and acids for unblocking blocked 2-AA for use in glycan labeling and analysis.