公开(公告)号：US20240308958A1

公开(公告)日：2024-09-19

申请号：US18571090

申请日：2022-06-14

Applicant: BIOGEN MA INC.

Inventor： Daw-long Albert KWOK ,  Chao Fei ,  Erwin Irdam ,  Donald Walker ,  Markus Grohmann ,  Jens Mohr ,  Janina Bucher

IPC: C07D207/404

CPC classification number: C07D207/404

Abstract: Disclosed is a method of preparing diroximel fumarate represented by the following structural formula (I) The method comprises reacting ethy lene carbonate with succinimide to form a hydroxyethyl succinimide intermediate; and reacting the intermediate with monomethyl fumarate to form the product compound.