公开(公告)号：US20240400506A1

公开(公告)日：2024-12-05

申请号：US18692541

申请日：2022-09-16

Applicant: BIOGEN MA INC.

Inventor： Liang Chen ,  Erwin Irdam ,  Daw-long Albert Kwok ,  Nocole Madden ,  John Mascho

IPC: C07D207/404 ,  A61K9/20 ,  A61K31/4015

Abstract: Many active pharmaceutical ingredients (API) are available in tablet form. Particles of the API should have a favorable compaction profile in order to be compressed into tablets, especially when the API is present in a large weight percentage in the tablet. Disclosed herein are particles of diroximel fumarate having improved characteristic for tablet formation, and methods of producing the same.