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1.发明申请MICROFLUIDIC DEVICES FOR THE RAPID AND AUTOMATED PROCESSING OF SAMPLE POPULATIONS 审中-公开用于快速和自动处理样本人口的微流体装置公开(公告)号：US20160016169A1
公开(公告)日：2016-01-21
申请号：US14772156
申请日：2014-03-05
Inventor： Adela Ben-Yakar , Navid Ghorashian , Sertan Kutal Gökçe , Sam Xun Guo , William Neil Everett , Frederic Bourgeois
IPC: B01L3/00 , G01N33/483
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L2200/027 , B01L2200/0652 , B01L2200/0668 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/0877 , B01L2400/0487 , B01L2400/06 , B01L2400/0655 , G01N33/4833 , G01N2333/43534
Abstract: Microfluidic devices for the rapid and automated processing of sample populations are provided. Described are multiplexer tiplexer microfluidic devices configured to serially deliver a plurality of distinct sample populations to a sample processing element rapidly and automatically, without cross-contaminating the distinct sample populations. Also provided are microfluidic sample processing elements that can be used to rapidly and automatically manipulate and/or interrogate members of a sample population. The microfluidic devices can be used to improve the throughput and quality of experiments involving model organisms, such as C. elegans.
Abstract translation: 提供了用于快速和自动处理样品种群的微流体装置。 描述的是复用器复合器微流体装置，其被配置为将多个不同样本群体快速和自动地串行地递送到样品处理元件，而不会交叉污染不同的样本群体。 还提供了微流体样品处理元件，其可用于快速和自动地操纵和/或询问样品群体的成员。 微流体装置可以用于提高涉及模型生物体如秀丽隐杆线虫的实验的生产量和质量。
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公开(公告)号：US11192109B2
公开(公告)日：2021-12-07
申请号：US16038415
申请日：2018-07-18
Inventor： Adela Ben-Yakar , Navid Ghorashian , Sertan Kutal Gökçe , Sam Xun Guo , William Neil Everett , Frederic Bourgeois
IPC: B01L3/00 , G01N33/483
Abstract: Microfluidic devices for the rapid and automated processing of sample populations are provided. Described are multiplexer microfluidic devices configured to serially deliver a plurality of distinct sample populations to a sample processing element rapidly and automatically, without cross-contaminating the distinct sample populations. Also provided are microfluidic sample processing elements that can be used to rapidly and automatically manipulate and/or interrogate members of a sample population. The microfluidic devices can be used to improve the throughput and quality of experiments involving model organisms, such as C. elegans.
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公开(公告)号：US10539554B2
公开(公告)日：2020-01-21
申请号：US15522116
申请日：2015-10-27
Inventor： Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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公开(公告)号：US20240094193A1
公开(公告)日：2024-03-21
申请号：US18449351
申请日：2023-08-14
Inventor： Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
CPC classification number: G01N33/5085 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L3/502761 , G01N21/05 , G01N21/6458 , G01N33/502 , G01N35/00029 , G01N35/00871 , G06V20/693 , G06V20/695 , B01L2200/0668 , B01L2300/023 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2300/14 , B01L2400/0487 , B01L2400/086 , G01N2021/6482 , G01N2035/00148 , G01N2201/12
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, maybe controlled via hydraulic pressure.
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Patent Agency Ranking
公开(公告)号：US20200158717A1
公开(公告)日：2020-05-21
申请号：US16747432
申请日：2020-01-20
Inventor： Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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公开(公告)号：US20170336394A1
公开(公告)日：2017-11-23
申请号：US15522116
申请日：2015-10-27
Inventor： Adela Ben-Yaker , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
CPC classification number: G01N33/5085 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L3/502761 , B01L2200/0668 , B01L2300/023 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2300/14 , B01L2400/0487 , B01L2400/086 , G01N21/05 , G01N21/6458 , G01N33/502 , G01N35/00029 , G01N35/00871 , G01N2021/6482 , G01N2035/00148 , G01N2201/12 , G06K9/00134 , G06K9/0014
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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公开(公告)号：US11726084B2
公开(公告)日：2023-08-15
申请号：US16747432
申请日：2020-01-20
Inventor： Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
CPC classification number: G01N33/5085 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L3/502761 , G01N21/05 , G01N21/6458 , G01N33/502 , G01N35/00029 , G01N35/00871 , G06V20/693 , G06V20/695 , B01L2200/0668 , B01L2300/023 , B01L2300/0654 , B01L2300/087 , B01L2300/0816 , B01L2300/0864 , B01L2300/14 , B01L2400/0487 , B01L2400/086 , G01N2021/6482 , G01N2035/00148 , G01N2201/12
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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公开(公告)号：US20190232288A1
公开(公告)日：2019-08-01
申请号：US16038415
申请日：2018-07-18
Inventor： Adela Ben-Yakar , Navid Ghorashian , Sertan Kutal Gökçe , Sam Xun Guo , William Neil Everett , Frederic Bourgeois
IPC: B01L3/00 , G01N33/483
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L2200/027 , B01L2200/0652 , B01L2200/0668 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/0877 , B01L2400/0487 , B01L2400/06 , B01L2400/0655 , G01N33/4833 , G01N2333/43534
Abstract: Microfluidic devices for the rapid and automated processing of sample populations are provided. Described are multiplexer microfluidic devices configured to serially deliver a plurality of distinct sample populations to a sample processing element rapidly and automatically, without cross-contaminating the distinct sample populations. Also provided are microfluidic sample processing elements that can be used to rapidly and automatically manipulate and/or interrogate members of a sample population. The microfluidic devices can be used to improve the throughput and quality of experiments involving model organisms, such as C. elegans.
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公开(公告)号：US10052631B2
公开(公告)日：2018-08-21
申请号：US14772156
申请日：2014-03-05
Inventor： Adela Ben-Yakar , Navid Ghorashian , Sertan Kutal Gökçe , Sam Xun Guo , William Neil Everett , Frederic Bourgeois
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L2200/027 , B01L2200/0652 , B01L2200/0668 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/0877 , B01L2400/0487 , B01L2400/06 , B01L2400/0655 , G01N33/4833 , G01N2333/43534
Abstract: Microfluidic devices for the rapid and automated processing of sample populations are provided. Described are multiplexer microfluidic devices configured to serially deliver a plurality of distinct sample populations to a sample processing element rapidly and automatically, without cross-contaminating the distinct sample populations. Also provided are microfluidic sample processing elements that can be used to rapidly and automatically manipulate and/or interrogate members of a sample population. The microfluidic devices can be used to improve the throughput and quality of experiments involving model organisms, such as C. elegans.
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