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公开(公告)号:US10539554B2
公开(公告)日:2020-01-21
申请号:US15522116
申请日:2015-10-27
Inventor: Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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2.
公开(公告)号:US20180267284A1
公开(公告)日:2018-09-20
申请号:US15547615
申请日:2016-01-29
Inventor: Adela Ben-Yakar , Ki Hyun Kim , Evan Hegarty , Sertan Kutal Gokce , Sudip Mondal
CPC classification number: G02B21/0084 , G02B21/0048 , G02B21/0076 , G02B21/008 , G02B21/0088 , G06T15/08 , H01S3/101
Abstract: A laser scanning system for capturing an image of a specimen is described herein. The laser scanning system includes a light source configured to emit a light beam for illuminating the specimen, a scanning unit including a plurality of reflectors for scanning the light beam along first and second axes, and a data acquisition unit configured to control acquisition of the image. The laser scanning system can include a control circuit configured to receive a reference clock signal for the first reflector and generate a synchronization clock signal based on the reference clock signal. The laser scanning system can include a synchronization controller configured to control the scanning unit and the data acquisition unit. The synchronization controller can be configured to receive the synchronization clock signal, receive a plurality of imaging parameters, and generate a plurality of control signals based on the synchronization clock signal and the imaging parameters.
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公开(公告)号:US11714270B2
公开(公告)日:2023-08-01
申请号:US16921011
申请日:2020-07-06
Inventor: Adela Ben-Yakar , Ki Hyun Kim , Evan Hegarty , Sertan Kutal Gokce , Sudip Mondal
CPC classification number: G02B21/0084 , G02B21/008 , G02B21/0048 , G02B21/0076 , G02B21/0088 , G06T15/08 , H01S3/101
Abstract: A laser scanning system for capturing an image of a specimen is described herein. The laser scanning system includes a light source configured to emit a light beam for illuminating the specimen, a scanning unit including a plurality of reflectors for scanning the light beam along first and second axes, and a data acquisition unit configured to control acquisition of the image. The laser scanning system can include a control circuit configured to receive a reference clock signal for the first reflector and generate a synchronization clock signal based on the reference clock signal. The laser scanning system can include a synchronization controller configured to control the scanning unit and the data acquisition unit. The synchronization controller can be configured to receive the synchronization clock signal, receive a plurality of imaging parameters, and generate a plurality of control signals based on the synchronization clock signal and the imaging parameters.
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公开(公告)号:US11726084B2
公开(公告)日:2023-08-15
申请号:US16747432
申请日:2020-01-20
Inventor: Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
CPC classification number: G01N33/5085 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L3/502761 , G01N21/05 , G01N21/6458 , G01N33/502 , G01N35/00029 , G01N35/00871 , G06V20/693 , G06V20/695 , B01L2200/0668 , B01L2300/023 , B01L2300/0654 , B01L2300/087 , B01L2300/0816 , B01L2300/0864 , B01L2300/14 , B01L2400/0487 , B01L2400/086 , G01N2021/6482 , G01N2035/00148 , G01N2201/12
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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公开(公告)号:US20240094193A1
公开(公告)日:2024-03-21
申请号:US18449351
申请日:2023-08-14
Inventor: Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
CPC classification number: G01N33/5085 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L3/502761 , G01N21/05 , G01N21/6458 , G01N33/502 , G01N35/00029 , G01N35/00871 , G06V20/693 , G06V20/695 , B01L2200/0668 , B01L2300/023 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2300/14 , B01L2400/0487 , B01L2400/086 , G01N2021/6482 , G01N2035/00148 , G01N2201/12
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, maybe controlled via hydraulic pressure.
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6.
公开(公告)号:US20200333574A1
公开(公告)日:2020-10-22
申请号:US16921011
申请日:2020-07-06
Inventor: Adela Ben-Yakar , Ki Hyun Kim , Evan Hegarty , Sertan Kutal Gokce , Sudip Mondal
Abstract: A laser scanning system for capturing an image of a specimen is described herein. The laser scanning system includes a light source configured to emit a light beam for illuminating the specimen, a scanning unit including a plurality of reflectors for scanning the light beam along first and second axes, and a data acquisition unit configured to control acquisition of the image. The laser scanning system can include a control circuit configured to receive a reference clock signal for the first reflector and generate a synchronization clock signal based on the reference clock signal. The laser scanning system can include a synchronization controller configured to control the scanning unit and the data acquisition unit. The synchronization controller can be configured to receive the synchronization clock signal, receive a plurality of imaging parameters, and generate a plurality of control signals based on the synchronization clock signal and the imaging parameters.
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公开(公告)号:US20200158717A1
公开(公告)日:2020-05-21
申请号:US16747432
申请日:2020-01-20
Inventor: Adela Ben-Yakar , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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公开(公告)号:US20170336394A1
公开(公告)日:2017-11-23
申请号:US15522116
申请日:2015-10-27
Inventor: Adela Ben-Yaker , Evan Hegarty , Sudip Mondal , Navid Ghorashian , Sertan Kutal Gökçe , Christopher Martin
CPC classification number: G01N33/5085 , B01L3/502715 , B01L3/502723 , B01L3/502746 , B01L3/502761 , B01L2200/0668 , B01L2300/023 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2300/14 , B01L2400/0487 , B01L2400/086 , G01N21/05 , G01N21/6458 , G01N33/502 , G01N35/00029 , G01N35/00871 , G01N2021/6482 , G01N2035/00148 , G01N2201/12 , G06K9/00134 , G06K9/0014
Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.
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