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公开(公告)号：US09717453B2
公开(公告)日：2017-08-01
申请号：US14395802
申请日：2013-04-19
Applicant: BIOGEN MA INC.
Inventor： Diego Cadavid , David Erlanger , John DeLuca , Ralph Benedict , Frederick W. Foley , Jeffrey A. Wilken
CPC classification number: A61B5/168 , A61B5/16 , G06F19/00 , G09B5/06 , G09B19/00 , G16H50/20 , G16H50/30
Abstract: Methods, systems and kits for the identification, assessment and/or treatment of a subject having multiple sclerosis are disclosed.
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公开(公告)号：US10435467B2
公开(公告)日：2019-10-08
申请号：US15541944
申请日：2016-01-08
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
IPC: A61K38/00 , C07K16/28 , A61K38/21 , A61K39/395 , A61K45/06 , C07K14/705 , A61K39/00
Abstract: Methods, compositions and kits comprising an anti-LINGO antibody molecule are described herein useful for detecting and/or treating a CNS demyelinating disease.
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公开(公告)号：US20210277111A1
公开(公告)日：2021-09-09
申请号：US17127324
申请日：2020-12-18
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
IPC: C07K16/28 , A61K38/21 , A61K39/395 , A61K45/06
Abstract: Methods, compositions and kits are described herein useful for detecting and/or treating a CNS demyelinating disease.
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公开(公告)号：US20200276303A1
公开(公告)日：2020-09-03
申请号：US16708695
申请日：2019-12-10
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
Abstract: Methods and compositions for enhancing one or more of: myelination, re-myelination, oligodendrocyte numbers, or neuroaxonal protection, while ameliorating an inflammatory condition in a human subject are disclosed. In certain embodiments, the methods and compositions described herein include a reparative agent (e.g., a LINGO-1 antagonist) and an immunomodulatory agent, in combination. Thus, methods, compositions and kits described herein can be useful for treating a CNS demyelinating disease.
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公开(公告)号：US20210260185A1
公开(公告)日：2021-08-26
申请号：US17107554
申请日：2020-11-30
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
Abstract: Methods and compositions for enhancing one or more of: myelination, re-myelination, oligodendrocyte numbers, or neuroaxonal protection, while ameliorating an inflammatory condition in a human subject are disclosed. In certain embodiments, the methods and compositions described herein include a reparative agent (e.g., a LINGO-1 antagonist) and an immunomodulatory agent, in combination. Thus, methods, compositions and kits described herein can be useful for treating a CNS demyelinating disease.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20200031924A1
公开(公告)日：2020-01-30
申请号：US16316428
申请日：2017-07-12
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Lei Xu , Lin Xu
Abstract: Dosage regimens, methods, compositions and kits are described herein useful for detecting and/or treating a CNS demyelinating disease.
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公开(公告)号：US20190038744A1
公开(公告)日：2019-02-07
申请号：US15900369
申请日：2018-02-20
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
Abstract: Methods and compositions for enhancing one or more of: myelination, re-myelination, oligodendrocyte numbers, or neuroaxonal protection, while ameliorating an inflammatory condition in a human subject are disclosed. In certain embodiments, the methods and compositions described herein include a reparative agent (e.g., a LINGO-1 antagonist) and an immunomodulatory agent, in combination. Thus, methods, compositions and kits described herein can be useful for treating a CNS demyelinating disease.
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公开(公告)号：US20210403556A1
公开(公告)日：2021-12-30
申请号：US17174610
申请日：2021-02-12
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Lei Xu , Lin Xu
Abstract: Dosage regimens, methods, compositions and kits are described herein useful for detecting and/or treating a CNS demyelinating disease.
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公开(公告)号：US20200216533A1
公开(公告)日：2020-07-09
申请号：US16589322
申请日：2019-10-01
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
IPC: C07K16/28 , A61K38/21 , A61K39/395 , A61K45/06
Abstract: Methods, compositions and kits are described herein useful for detecting and/or treating a CNS demyelinating disease.
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公开(公告)号：US20180148505A1
公开(公告)日：2018-05-31
申请号：US15541944
申请日：2016-01-08
Applicant: Biogen MA Inc.
Inventor： Diego Cadavid , Sha Mi
IPC: C07K16/28 , A61K39/395 , A61K45/06 , A61K38/21 , A61K39/00
CPC classification number: C07K16/2803 , A61K38/215 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/21 , C07K2317/76
Abstract: Methods, compositions and kits comprising an anti-LINGO antibody molecule are described herein useful for detecting and/or treating a CNS demyelinating disease.
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