公开(公告)号：US20190064147A1

公开(公告)日：2019-02-28

申请号：US15544315

申请日：2016-01-18

Applicant: Biogen MA Inc.

Inventor： Mark Krebs ,  Mariana Dimitrova ,  Kapil Gupta ,  Shantanu Sule ,  Randall Mauldin ,  Adnan Zunic ,  Lori Karpes

IPC: G01N33/50 ,  A61K47/12 ,  G01N33/68 ,  A61K47/18 ,  A61K47/26 ,  G01N33/84 ,  G01N33/94 ,  C07K1/113 ,  G01N33/15

Abstract: Provided herein, in some aspects, are methods of developing a biological therapeutic product. The methods can be used to formulate a biological therapeutic agent or screen biological therapeutic agents.

公开(公告)号：US20180264112A1

公开(公告)日：2018-09-20

申请号：US15543653

申请日：2016-01-15

Applicant: Biogen MA Inc.

Inventor： Mark Krebs ,  Adnan Zunic ,  Tia Estey ,  Shantanu Sule ,  Margaret McGrath ,  Lori Karpes ,  Yana Kravets

IPC: A61K39/395 ,  C07K16/28 ,  A61K47/12 ,  A61K47/18 ,  A61K47/26 ,  A61K9/00 ,  A61K47/22

CPC classification number: A61K39/39591 ,  A61K9/0019 ,  A61K47/12 ,  A61K47/183 ,  A61K47/22 ,  A61K47/26 ,  A61K2039/54 ,  C07K16/2878 ,  C07K2317/56 ,  C07K2317/565

Abstract: Provided herein, in some aspects, are low viscosity, low aggregation propensity, high anti-CD40 antibody concentration formulations.