公开(公告)号：US20210309719A1

公开(公告)日：2021-10-07

申请号：US17216769

申请日：2021-03-30

Applicant: Biogen MA Inc.

Inventor： Kevin Maloney ,  Ke Gong ,  Roy Alston

IPC: C07K14/715 ,  A61K38/17 ,  A61K47/02 ,  A61K9/00 ,  A61P29/00 ,  C07K19/00 ,  A61K47/68 ,  A61K47/26

Abstract: Aspects of the invention are directed to arginine-free polypeptide-containing compositions and methods for treating disorders associated with inflammation or the autoimmune response. In particular, the polypeptide is etanercept.

公开(公告)号：US11834491B2

公开(公告)日：2023-12-05

申请号：US17216769

申请日：2021-03-30

Applicant: Biogen MA Inc.

Inventor： Kevin Maloney ,  Ke Gong ,  Roy Alston

IPC: A61K38/17 ,  A61K47/68 ,  A61K9/00 ,  A61K47/26 ,  A61K47/02 ,  C07K19/00 ,  C07K14/715 ,  A61P29/00 ,  C07K14/705 ,  C07K14/525 ,  C07K16/24

CPC classification number: C07K14/7151 ,  A61K9/0019 ,  A61K38/1793 ,  A61K47/26 ,  A61K47/68 ,  C07K19/00 ,  A61K47/02 ,  A61P29/00 ,  C07K14/525 ,  C07K14/70578 ,  C07K16/241 ,  C07K2319/30

Abstract: Aspects of the invention are directed to arginine-free polypeptide-containing compositions and methods for treating disorders associated with inflammation or the autoimmune response. In particular, the polypeptide is etanercept.

公开(公告)号：US20170355729A1

公开(公告)日：2017-12-14

申请号：US15532578

申请日：2015-12-02

Applicant: Biogen MA Inc.

Inventor： Matthew Westoby ,  Alex Brinkmann ,  Ryan Haverstock ,  Roy Alston

IPC: C07K1/34 ,  C07K16/24 ,  A61K39/395

CPC classification number: C07K1/34 ,  A61K39/39591 ,  C07K16/241 ,  C07K2317/24

Abstract: Disclosed herein are methods of purifying monoclonal antibodies and related compositions.