公开(公告)号：US20250082280A1

公开(公告)日：2025-03-13

申请号：US18829089

申请日：2024-09-09

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Alessio TAMBORINI ,  Morteza GHARIB ,  Arian AGHILINEJAD

IPC: A61B5/00 ,  A61B5/02 ,  A61B5/021 ,  A61B5/024 ,  A61B5/025

Abstract: The disclosure relates to techniques for transferring a pulse pressure waveform signal of a peripheral vascular site to a central vascular site. In some implementations, a method includes: obtaining a time-domain representation of a first pulse pressure waveform signal of a brachial artery of a subject; converting the time-domain representation of the first pulse pressure waveform signal to a frequency-domain representation of the first pulse pressure waveform signal; selecting a first plurality of frequency components of the frequency-domain representation of the first pulse pressure waveform signal; predicting, using a non-linear mapping, based on the first plurality of frequency components, a second plurality of frequency components of a frequency-domain representation of a second pulse pressure waveform signal of an ascending aorta or left ventricle of the subject; and converting the frequency-domain representation of the second pulse pressure waveform signal to a time-domain representation of the second pulse pressure waveform signal.