公开(公告)号：US20240076650A1

公开(公告)日：2024-03-07

申请号：US18260560

申请日：2022-01-26

Applicant: CYTIVA BIOPROCESS R&D AB

Inventor： Peter Lundback ,  Ronnie Palmgren ,  Ola Lind ,  Nils Norrman ,  Helen Cheek ,  Susana Brito Dos Santos ,  Per Denker

IPC: C12N15/10 ,  B01D15/38 ,  B01J20/26 ,  B01J20/28 ,  B01J20/289

CPC classification number: C12N15/101 ,  B01D15/3819 ,  B01J20/265 ,  B01J20/28035 ,  B01J20/28038 ,  B01J20/289 ,  B01J2220/52

Abstract: The invention relates to processes for purification of poly-tagged products, such as mRNA, from synthetic or biological compositions. The process involves contacting the composition with a oligo d (T)-functionalized chromatography medium comprising a convection-based chromatography material.