公开(公告)号：US20220258130A1

公开(公告)日：2022-08-18

申请号：US17735882

申请日：2022-05-03

Applicant: Cytiva BioProcess R&D AB

Inventor： Ann Catharina Bergh ,  Mattias Algotsson ,  Tania Ahmad ,  Therese Graner

IPC: B01J20/289 ,  B01D15/38 ,  B01J20/28 ,  B01J20/32

Abstract: The present invention relates to a novel chromatography media, more closely a novel IMAC (Immobilized Metal Affinity Chromatography) media. The novel chromatography media comprises a pentaligand and provides high dynamic binding capacity as well as high purity of the sample proteins purified on the media of the invention.

公开(公告)号：US11014069B2

公开(公告)日：2021-05-25

申请号：US15769400

申请日：2016-10-28

Applicant: Cytiva BioProcess R&D AB

Inventor： Nils Norrman ,  Mattias Algotsson ,  Stefan D. Eriksson

IPC: B01J20/24 ,  B01J20/29 ,  B01J20/30 ,  B01J20/28 ,  B01J20/26 ,  B01J20/32 ,  B01D15/38 ,  B01D15/36

Abstract: The present invention relates to a method to improve chromatography beads. More closely, the invention relates to a novel method for production of dextran-containing porous media and chromatography media produced with this method. In the method, the chromatography media is subjected to dextranase-treatment leading to improved pressure-flow properties of the media.