公开(公告)号：US20230146223A1

公开(公告)日：2023-05-11

申请号：US17914974

申请日：2021-06-18

Applicant: DALIAN UNIVERSITY OF TECHNOLOGY

Inventor： Xiaobin JIANG ,  Peipei LI ,  Menghang LI ,  Zhijie YUAN ,  Gaohong HE ,  Wu XIAO ,  Xiangcun LI ,  Xuemei WU

IPC: C12N15/10 ,  B33Y80/00

CPC classification number: C12N15/1006 ,  B33Y80/00 ,  B29C64/124

Abstract: The present invention discloses a nucleic acids extraction system and method based on a 3D-printed microdevice, and belongs to the technical field of nucleic acids extraction. The nucleic acids extraction system is a monomer 3D-printed microdevice or a 3D-printed microdevice prepared by 3D printing technologies, the monomer 3D-printed microdevice comprises a nucleic acids binding region and a handle region, and the 3D-printed microdevice is composed of more than two monomer 3D-printed microdevices through a joining region; and the nucleic acids binding region is made of photosensitive resin or thermoplastic. An extraction method for the nucleic acids extraction system based on a 3D-printed microdevice is used to bind, clean and elute nucleic acids by moving the monomer 3D-printed microdevice or the 3D-printed microdevice among a solution containing target nucleic acids, a washing buffer and an elution buffer.