-
公开(公告)号:US20240257920A1
公开(公告)日:2024-08-01
申请号:US18565716
申请日:2022-05-27
Applicant: DH Technologies Development Pte. Ltd.
Inventor: Lyle BURTON , Carolyn CARKNER , Eva DUCHOSLAV
CPC classification number: G16C20/20 , G16C20/70 , H01J49/0045
Abstract: In one aspect, a computer implemented method for determining expected cleavage products of a macromolecule includes defining at least one residue of the macromolecule as having a core and at least one linker, where said at least one linker is defined as a sequence of two or more structural units that are coupled to one another via one or more chemical bonds. A digital data processor can be utilized to determine one or more expected bond cleavages, if any, between the structural units of said at least one linker and between adjacent residues when the macromolecule undergoes cleavage, e.g., in response to application of energy thereto, so as to predict expected cleavage products of the macromolecule.