公开(公告)号：US20220139690A1

公开(公告)日：2022-05-05

申请号：US17427428

申请日：2020-02-03

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Thomas R. Covey ,  Chang Liu ,  Stephen A Tate

IPC: H01J49/16 ,  H01J49/04 ,  G01N30/72

Abstract: A device that produces charged droplets whose composition is optimized for the creation of ions by electro spray composed of: a transport device that is operative to transfer sample components from a liquid sample to a processing chamber, a flowing stream of liquid through the processing chamber into which the samples are deposited, a controller mechanism operative to control the amount of sample transferred, a transport tube through which the flowing liquid containing the sample is directed to an electro spray emitter with a high electric field at the exit, a flow of expanding gas surrounding the electro spray emitter creating a pressure drop at the exit, and, a mass spectrometer for measuring the number of ions produced from the charged droplets emanating from the emitter; wherein the dilution of the sample in the processing chamber and transport fluid is from 100 to 10,000-fold.