公开(公告)号：US20200264144A1

公开(公告)日：2020-08-20

申请号：US16865696

申请日：2020-05-04

Applicant: DIONEX CORPORATION

Inventor： Manikandan JAYARAMAN ,  Christopher A. POHL ,  Charanjit SAINI

IPC: G01N30/96 ,  B01J47/02 ,  B01D15/20 ,  B01J41/07 ,  B01J39/07 ,  B01J39/05 ,  B01J41/20 ,  B01J39/26 ,  B01J39/20 ,  B01D15/36

Abstract: An ion exchange chromatographic packing material is described that includes support resin particles and a copolymer grafted to the support resin particles. The copolymer includes polymerized functional monomers such as a first ion exchange group monomer and a second ion exchange group monomer. At a first pH, the first ion exchange group monomer is configured to have a first charge at a first pH, and the second ion exchange group monomer is configured to have a net neutral charge. At a second pH, the first ion exchange group monomer is configured to have the first charge at a second pH, and the second ion exchange group monomer is configured to have a second charge at the second pH where the first charge and second charge both have a same polarity.

公开(公告)号：US20200047176A1

公开(公告)日：2020-02-13

申请号：US16101264

申请日：2018-08-10

Applicant: DIONEX CORPORATION

Inventor： Charanjit SAINI ,  Christopher A. POHL

IPC: B01J41/13 ,  C08L63/00 ,  B01J41/20 ,  C08L79/02

Abstract: An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer. The crosslinked ethanolamine condensation polymer layer can be covalently attached to the base condensation polymer layer. The crosslinked ethanolamine condensation polymer layer can be formed by a condensation reaction product of a polyepoxide compound and ethanolamine. The glycidol condensation layer can be formed by the treatment of glycidol. The anion exchange stationary phase are suitable for separating a variety of haloacetic acids and common inorganic anions in a single chromatographic run in less than 20 to 35 minutes.

公开(公告)号：US20190291094A1

公开(公告)日：2019-09-26

申请号：US15928384

申请日：2018-03-22

Applicant: DIONEX CORPORATION

Inventor： Charanjit SAINI ,  Christopher A. POHL

IPC: B01J41/20 ,  B01J41/13 ,  B01J41/04 ,  C08J5/22 ,  B01D15/36

Abstract: An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer. The crosslinked ethanolamine condensation polymer layer can be covalently attached to the base condensation polymer layer. The crosslinked ethanolamine condensation polymer layer can be formed by a condensation reaction product of a polyepoxide compound and ethanolamine. The glycidol condensation layer can be formed by the treatment of glycidol. The anion exchange stationary phase are suitable for separating a variety of haloacetic acids and common inorganic anions in a single chromatographic run in less than 20 to 30 minutes.

公开(公告)号：US20160370329A1

公开(公告)日：2016-12-22

申请号：US14744348

申请日：2015-06-19

Applicant: DIONEX CORPORATION

Inventor： Manikandan JAYARAMAN ,  Christopher A. POHL ,  Charanjit SAINI

IPC: G01N30/96 ,  B01D15/36 ,  B01D15/20 ,  B01J39/26 ,  B01J47/02

CPC classification number: G01N30/96 ,  B01D15/206 ,  B01D15/362 ,  B01J39/05 ,  B01J39/07 ,  B01J39/20 ,  B01J39/26 ,  B01J41/07 ,  B01J41/20 ,  B01J47/02

Abstract: An ion exchange chromatographic packing material is described that includes support resin particles and a copolymer grafted to the support resin particles. The copolymer includes polymerized functional monomers such as a first ion exchange group monomer and a second ion exchange group monomer. At a first pH, the first ion exchange group monomer is configured to have a first charge at a first pH, and the second ion exchange group monomer is configured to have a net neutral charge. At a second pH, the first ion exchange group monomer is configured to have the first charge at a second pH, and the second ion exchange group monomer is configured to have a second charge at the second pH where the first charge and second charge both have a same polarity.

Abstract translation: 描述了一种离子交换色谱填充材料，其包括载体树脂颗粒和接枝到载体树脂颗粒上的共聚物。 共聚物包括聚合的官能单体如第一离子交换基团单体和第二离子交换基团单体。 在第一pH值下，第一离子交换基团单体被配置为在第一pH下具有第一电荷，并且第二离子交换基团单体构造成具有净中性电荷。 在第二pH下，第一离子交换基团单体被配置为在第二pH下具有第一电荷，并且第二离子交换基团单体被配置为在第一电荷和第二电荷都具有的第二pH下具有第二电荷 相同的极性。