公开(公告)号：US20220097024A1

公开(公告)日：2022-03-31

申请号：US17545466

申请日：2021-12-08

Applicant: DIONEX CORPORATION

Inventor： Christopher A. POHL ,  John M. RIVIELLO

IPC: B01J20/28 ,  B01J20/26 ,  G01N1/40 ,  B01L3/00 ,  B01J20/32 ,  B01J20/281

Abstract: A carrier for adsorption a compound, comprising a support; and a shrink-fitted monolithic body attached to and surrounding at least a portion of the support. The monolithic body can be porous and configured to bind compounds in a solution either for the isolation or depletion of the compounds from the solution.

公开(公告)号：US20190049352A1

公开(公告)日：2019-02-14

申请号：US16160925

申请日：2018-10-15

Applicant: DIONEX CORPORATION

Inventor： Xiaodong LIU ,  Christopher A. POHL

IPC: G01N1/40 ,  C07F7/21 ,  B01J20/32 ,  B01J20/286 ,  B01J20/289 ,  B01J20/287

Abstract: Ligand compositions and stationary phases comprising polyhedral oligomeric silsesquioxane moieties are incorporated in to chromatographic stationary phases, and these phases are incorporated into chromatography devices, such as columns. The compositions and devices are of use to separate molecular mixtures.

公开(公告)号：US20170136465A1

公开(公告)日：2017-05-18

申请号：US15419905

申请日：2017-01-30

Applicant: DIONEX CORPORATION

Inventor： Christopher A. POHL ,  Rosanne W. SLINGSBY ,  Jing HONG

IPC: B01L3/00 ,  B01J39/20 ,  B01J41/14 ,  B01J47/018 ,  G01N30/24 ,  C08J5/20 ,  C08J9/28 ,  G01N30/96 ,  G01N30/20 ,  B01D15/36 ,  B01J47/022

CPC classification number: B01L3/5635 ,  B01D15/361 ,  B01J39/20 ,  B01J41/14 ,  B01J47/018 ,  B01J47/022 ,  B01L3/502 ,  B01L2200/026 ,  B01L2300/042 ,  B01L2300/046 ,  B01L2300/049 ,  B01L2300/0681 ,  B01L2300/0832 ,  B01L2300/123 ,  B01L2400/0478 ,  C08J5/20 ,  C08J9/283 ,  C08J2205/044 ,  C08J2205/05 ,  C08J2325/06 ,  C08J2425/02 ,  C08J2425/06 ,  G01N30/20 ,  G01N30/24 ,  G01N30/96 ,  G01N35/10 ,  G01N35/1095 ,  G01N2035/0441

Abstract: A method of making an ion exchange foam is described. The method includes forming an aqueous phase by suspending an ion exchange resin in an aqueous solvent. An organic phase is formed by mixing at least a divinylbenzene, a monomer, and a surfactant. The formed aqueous phase is mixed with the formed organic phase to form an emulsion. The emulsion is polymerized to form the ion exchange foam. The ion exchange foam can be used with a plurality of sample vials in an autosampler.

公开(公告)号：US20160187306A1

公开(公告)日：2016-06-30

申请号：US14586339

申请日：2014-12-30

Applicant: DIONEX CORPORATION

Inventor： Christopher A. POHL ,  Rosanne W. SLINGSBY

IPC: G01N30/60 ,  G01N30/96

Abstract: A vial cap for removing a matrix component from a liquid sample is described. The vial cap includes a cap body, an inlet portion, and an outlet portion. The cap body is configured to have a slidable gas and liquid seal with a side wall of a sample vial. The inlet portion includes a counterbore section that holds a filter plug. The filter plug includes a polyethylene resin and a material selected from the group consisting of an ion exchange material and a reversed-phase material. The vial cap is adapted for solid phase extraction for use in an autosampler with a plurality of sample vials.

Abstract translation: 描述了用于从液体样品中去除基质组分的小瓶盖。 小瓶盖包括盖体，入口部分和出口部分。 盖体构造成具有与样品瓶的侧壁的可滑动气体和液体密封。 入口部分包括保持过滤嘴的沉孔部分。 过滤塞包括聚乙烯树脂和选自离子交换材料和反相材料的材料。 小瓶盖适用于固相萃取，用于具有多个样品瓶的自动进样器。

公开(公告)号：US20180024101A1

公开(公告)日：2018-01-25

申请号：US15716308

申请日：2017-09-26

Applicant: DIONEX CORPORATION

Inventor： Kannan SRINIVASAN ,  Christopher A. POHL

IPC: G01N30/86 ,  G01N30/96 ,  G01N30/04

CPC classification number: G01N30/8668 ,  G01N30/8675 ,  G01N30/96 ,  G01N2030/047

Abstract: An automated method of calibrating a chromatography system and analyzing a sample is described. The method includes forming diluted standard solutions that are injected into a chromatography column. The detected peaks can be identified based on a first predetermined calibration ratio associated with the standard solution. Once the chromatography system is calibrated, samples can be chromatographically analyzed where the measured peaks are identified and quantified in an automated manner.

公开(公告)号：US20160377516A1

公开(公告)日：2016-12-29

申请号：US15259422

申请日：2016-09-08

Applicant: DIONEX CORPORATION

Inventor： Christopher A. POHL ,  Kannan SRINIVASAN ,  SM Rahmat ULLAH

IPC: G01N1/40 ,  B01D11/04 ,  C08F220/34 ,  C08F220/06 ,  B01J20/26

CPC classification number: G01N1/405 ,  B01D11/04 ,  B01D11/0492 ,  B01J20/261 ,  C08F220/06 ,  C08F220/34 ,  C08F222/1006 ,  C08F228/02 ,  G01N1/10 ,  G01N1/34 ,  G01N1/4055 ,  G01N2001/4061

Abstract: A method of extracting an analyte from a sample is described where the sample includes water. The sample and polymeric drying agent are added to a container. The polymeric drying agent includes a cationic monomer, an anionic monomer, and a crosslinker. The polymeric drying agent is configured to sorb water from the sample.

公开(公告)号：US20150275380A1

公开(公告)日：2015-10-01

申请号：US14739357

申请日：2015-06-15

Applicant: DIONEX CORPORATION

Inventor： Yan LIU ,  Petr JANDIK ,  Christopher A. POHL

IPC: C25B9/18 ,  C25B1/02 ,  C25B3/00 ,  B01D15/16 ,  G01N30/34 ,  G01N30/16 ,  B01D15/36 ,  C25B13/00 ,  C25B1/14

CPC classification number: C25B9/18 ,  B01D15/166 ,  B01D15/361 ,  B01D61/44 ,  C25B1/02 ,  C25B1/14 ,  C25B3/00 ,  C25B13/00 ,  G01N30/16 ,  G01N30/34 ,  G01N30/96 ,  G01N2030/965 ,  Y02E60/34 ,  Y10T137/0318

Abstract: A system and method to generate a concentration gradient eluent flow are described. The concentration gradient eluent flow can include at least two different generants. A liquid can be pumped to an eluent generating device. A first controlling signal can be applied to a first eluent generator to generate a first generant. A second controlling signal can be applied to a second eluent generator to generate a second generant. Either the first and/or the second controlling signal can be varied as a function of time to generate the concentration gradient eluent flow.

Abstract translation: 描述了产生浓度梯度洗脱流的系统和方法。 浓度梯度洗脱液流可以包括至少两种不同的生成剂。 液体可以泵送到洗脱液生成装置。 第一控制信号可以应用于第一洗脱液发生器以产生第一发生器。 第二控制信号可以应用于第二淋洗液发生器以产生第二发生器。 第一和/或第二控制信号可以作为时间的函数而变化以产生浓度梯度洗脱液流。

公开(公告)号：US20210016266A1

公开(公告)日：2021-01-21

申请号：US17022304

申请日：2020-09-16

Applicant: THE BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM ,  DIONEX CORPORATION

Inventor： Purnendu K. DASGUPTA ,  Weixiong HUANG ,  Christopher A. POHL

IPC: B01J39/26 ,  G01N30/60 ,  B01J20/32 ,  B01J20/286 ,  B01D15/36 ,  B01D15/20 ,  B01D15/22 ,  B01J41/20 ,  B01J47/02

Abstract: Open tubular capillary columns for liquid and ion chromatography, based upon an ionically impermeable polyolefin capillary having a bore with a sulfonate-group- or amine-group-functionalized internal surface. The capillary columns may include a coating of ion exchanging nanoparticles electrostatically bound to the functionalized internal surface. The capillary columns may be made by exposing the interior surface to a sulfonating reagent comprising chlorosulfonic acid (CISO3H), preferably from 85 wt % to 95 wt % chlorosulfonic acid at a process temperature of 20 to 25° C. The interior surface may be subsequently exposed to an asymmetrical diamine to form a sulfonic mid-linkage to the diamine, i.e., to form a sulfonamide-linked, amine-group-functionalized internal surface. The coating may be provided by subsequently exposing the interior surface to an aqueous suspension of ion exchanging nanoparticles to electrostatically bond the ion exchanging nanoparticles to the functionalized internal surface.

公开(公告)号：US20200047176A1

公开(公告)日：2020-02-13

申请号：US16101264

申请日：2018-08-10

Applicant: DIONEX CORPORATION

Inventor： Charanjit SAINI ,  Christopher A. POHL

IPC: B01J41/13 ,  C08L63/00 ,  B01J41/20 ,  C08L79/02

Abstract: An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer. The crosslinked ethanolamine condensation polymer layer can be covalently attached to the base condensation polymer layer. The crosslinked ethanolamine condensation polymer layer can be formed by a condensation reaction product of a polyepoxide compound and ethanolamine. The glycidol condensation layer can be formed by the treatment of glycidol. The anion exchange stationary phase are suitable for separating a variety of haloacetic acids and common inorganic anions in a single chromatographic run in less than 20 to 35 minutes.

公开(公告)号：US20160084807A1

公开(公告)日：2016-03-24

申请号：US14490527

申请日：2014-09-18

Applicant: DIONEX CORPORATION

Inventor： Kannan SRINIVASAN ,  Christopher A. POHL

IPC: G01N30/86

CPC classification number: G01N30/8668 ,  G01N30/8675 ,  G01N30/96 ,  G01N2030/047

Abstract: An automated method of calibrating a chromatography system and analyzing a sample is described. The method includes forming diluted standard solutions that are injected into a chromatography column. The detected peaks can be identified based on a first predetermined calibration ratio associated with the standard solution. Once the chromatography system is calibrated, samples can be chromatographically analyzed where the measured peaks are identified and quantified in an automated manner.

Abstract translation: 描述了校准色谱系统和分析样品的自动化方法。 该方法包括形成注入色谱柱的稀释的标准溶液。 可以基于与标准溶液相关联的第一预定校准比来鉴定检测到的峰。 校准色谱系统后，可以对样品进行色谱分析，其中以自动方式鉴定和定量测定的峰。