公开(公告)号：US20200316145A1

公开(公告)日：2020-10-08

申请号：US16779792

申请日：2020-02-03

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Gregory Leyer ,  Arthur Ouwehand

IPC: A61K35/747 ,  A61K35/745 ,  C12N1/20

Abstract: The present invention provides probiotic compositions suitable for reducing the incidence and duration of human illness. In particular, the present invention provides methods and compositions suitable for preventing disease in young children. In some particularly preferred embodiments, the present invention finds use in the prevention respiratory disease in children.

公开(公告)号：US20140242034A1

公开(公告)日：2014-08-28

申请号：US14157488

申请日：2014-01-16

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Gregory Leyer ,  Arthur Ouwehand

IPC: A61K35/74

CPC classification number: A61K35/747 ,  A23L33/135 ,  A61K35/745

Abstract: The present invention provides probiotic compositions suitable for relieving symptoms associated with gastrointestinal disorders. In particular, the present invention provides compositions and methods to relieve symptoms associated with functional bowel disorders, irritable bowel syndrome, functional diarrhea, functional bloating, and other symptoms.

Abstract translation: 本发明提供适于缓解与胃肠道疾病相关的症状的益生菌组合物。 特别地，本发明提供减轻与功能性肠病，肠易激综合征，功能性腹泻，功能性腹胀等症状相关的症状的组合物和方法。

公开(公告)号：US20240245735A1

公开(公告)日：2024-07-25

申请号：US18364151

申请日：2023-08-02

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Heli Putaala ,  Sofia Forssten ,  Sampo Lahtinen ,  Arthur Ouwehand ,  Jaana Mättö ,  Harri Mäkivuokko ,  Janne Nikkilä

IPC: A61K35/747 ,  A23L33/00 ,  A23L33/135 ,  A61K35/745 ,  A61P1/04 ,  A61P1/12 ,  A61P1/14

CPC classification number: A61K35/747 ,  A23L33/135 ,  A23L33/30 ,  A61K35/745 ,  A61P1/04 ,  A61P1/12 ,  A61P1/14

Abstract: The present invention relates to bacteria and metabolites thereof that are capable of binding to A, B and/or O blood type antigens or which are acid and/or bile tolerant, their use in probiotic compositions and food products, and methods for their selection. The invention also relates to the use of said bacteria and metabolites for the prevention and/or treatment of gastrointestinal disorders.

公开(公告)号：US20160354419A9

公开(公告)日：2016-12-08

申请号：US14157488

申请日：2014-01-16

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Gregory Leyer ,  Arthur Ouwehand

IPC: A61K35/74

CPC classification number: A61K35/747 ,  A23L33/135 ,  A61K35/745

Abstract: The present invention provides probiotic compositions suitable for relieving symptoms associated with gastrointestinal disorders. In particular, the present invention provides compositions and methods to relieve symptoms associated with functional bowel disorders, irritable bowel syndrome, functional diarrhea, functional bloating, and other symptoms.

Abstract translation: 本发明提供适于缓解与胃肠道疾病相关的症状的益生菌组合物。 特别地，本发明提供减轻与功能性肠病，肠易激综合征，功能性腹泻，功能性腹胀等症状相关的症状的组合物和方法。

公开(公告)号：US20220354908A1

公开(公告)日：2022-11-10

申请号：US17579006

申请日：2022-01-19

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Heli Putaala ,  Sofia Forssten ,  Sampo Lahtinen ,  Arthur Ouwehand ,  Jaana Mättö ,  Harri Mäkivuokko ,  Inger Mattsby-Baltzer ,  Björn Andersch

IPC: A61K35/747 ,  A61P31/00 ,  C12Q1/28 ,  C12N1/20 ,  A61K35/745

Abstract: The present invention relates to bacteria and metabolites thereof that are capable of binding to vaginal cells and producing hydrogen peroxide, their use in probiotic compositions and food products and methods for their selection. The invention also relates to the use of said bacteria, metabolites and probiotic compositions for the prevention and/or treatment of urogenital disorders.

公开(公告)号：US20160008412A1

公开(公告)日：2016-01-14

申请号：US14860836

申请日：2015-09-22

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Heli Putaala ,  Arthur Ouwehand ,  Kirsti Tihonen ,  Nina Rautonen

IPC: A61K35/741 ,  A61K35/745 ,  A61K31/205 ,  A61K35/747

CPC classification number: A61K35/741 ,  A61K31/205 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747

Abstract: The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with Tight Junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.

Abstract translation: 本发明涉及用于治疗与紧结功能相关的病症的益生菌和/或益生菌的细胞裂解液的益生菌和/或可溶性代谢物，其特征在于益生菌，可溶性 将益生菌和/或益生菌的细胞裂解液的代谢物配制成局部给药。

公开(公告)号：US20200376045A1

公开(公告)日：2020-12-03

申请号：US16786079

申请日：2020-02-10

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Heli Anglenius ,  Kirsti Tiihonen ,  Nina Rautonen ,  Arthur Ouwehand

IPC: A61K35/741 ,  A61K31/205 ,  A61K35/745 ,  A61K35/747 ,  A61K35/744

Abstract: The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with Tight Junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.

公开(公告)号：US20200085888A1

公开(公告)日：2020-03-19

申请号：US16333770

申请日：2017-09-12

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Heli Putaala ,  Sofia Forssten ,  Sampo Lahtinen ,  Arthur Ouwehand ,  Jaana Mättö ,  Harri Mäkivuokko ,  Janne Nikkilä

IPC: A61K35/747 ,  A61K35/745 ,  A61P1/04 ,  A61P1/14 ,  A23L33/00 ,  A23L33/135 ,  A61P1/12

Abstract: The present invention relates to bacteria and metabolites thereof that are capable of binding to A, B and/or O blood type antigens or which are acid and/or bile tolerant, their use in probiotic compositions and food products, and methods for their selection. The invention also relates to the use of said bacteria and metabolites for the prevention and/or treatment of gastrointestinal disorders.

公开(公告)号：US10555977B2

公开(公告)日：2020-02-11

申请号：US15963493

申请日：2018-04-26

Applicant: DUPONT NUTRITION BIOSCIENCES APS

Inventor： Heli Anglenius ,  Kirsti Tiihonen ,  Nina Rautonen ,  Arthur Ouwehand

IPC: A61K35/741 ,  A61K31/205 ,  A61K35/745 ,  A61K35/747 ,  A61K35/744

Abstract: The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with Tight Junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.

公开(公告)号：US20190091270A1

公开(公告)日：2019-03-28

申请号：US15963439

申请日：2018-04-26

Applicant: Dupont Nutrition Biosciences Aps

Inventor： Gregory Leyer ,  Arthur Ouwehand

IPC: A61K35/747 ,  A23L33/135 ,  A61K35/745

Abstract: The present invention provides probiotic compositions suitable for relieving symptoms associated with gastrointestinal disorders. In particular, the present invention provides compositions and methods to relieve symptoms associated with functional bowel disorders, irritable bowel syndrome, functional diarrhea, functional bloating, and other symptoms.