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公开(公告)号：US20190298653A1
公开(公告)日：2019-10-03
申请号：US16301435
申请日：2017-05-11
Applicant: Dai YAMANOUCHI , SIGMA-TECHNOLOGY INC.
Inventor： Dai YAMANOUCHI , Yoshiaki TACHIBANA , Kosuke TACHIBANA
Abstract: Provided are an administrable aqueous solution to a living body and a method for manufacturing the same, the administrable aqueous solution having a function of supplying sufficient oxygen to peripheral cells, causing less damage and injury of cells under a hypoxic or anaerobic stimulation, and continuously exhibiting a sufficiently high and stable effect to protect cells. The administrable aqueous solution to a living body according to the present invention contains oxygen nanobubbles having a mean particle size of 30 nm or less and a density of 1016 bubbles per ml, preferably a mean particle size of 1 to 10 nm and a density 1017 bubbles or more per ml, respectively, as determined by a measurement with a cryo-transmission electron microscope by an ice-embedding method. The administrable aqueous solution to a living body according to the present invention contains oxygen nanobubbles which are generated by jetting an aqueous solution containing dissolved oxygen from the outside of a cylinder, the cylinder being provided with 2 or more small through holes formed in the circumferential direction, via the small through-holes under atmospheric pressure or higher and thus bringing the jetted solution into collision in such a manner that water hammer is concentrated at the center of the cylinder on the same plane parallel to a cross-section in a radial direction of the cylinder.
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公开(公告)号：US20200338000A1
公开(公告)日：2020-10-29
申请号：US16922027
申请日：2020-07-07
Applicant: Dai YAMANOUCHI , SIGMA-TECHNOLOGY INC.
Inventor： Dai YAMANOUCHI , Yoshiaki TACHIBANA , Kosuke TACHIBANA
Abstract: Provided is a method for manufacturing an administrable aqueous solution to a living body, the administrable aqueous solution having a function of supplying sufficient oxygen to peripheral cells, causing less damage and injury of cells under a hypoxic or anaerobic stimulation, and continuously exhibiting a sufficiently high and stable effect to protect cells. The administrable aqueous solution to a living body according to the present invention contains oxygen nanobubbles having a mean particle size of 30 nm or less and a density of 1016 bubbles per ml, preferably a mean particle size of 1 to 10 nm and a density 1017 bubbles or more per ml, respectively, as determined by a measurement with a cryo-transmission electron microscope by an ice-embedding method. The administrable aqueous solution to a living body according to the present invention contains oxygen nanobubbles which are generated by jetting an aqueous solution containing dissolved oxygen from the outside of a cylinder, the cylinder being provided with 2 or more small through holes formed in the circumferential direction, via the small through-holes under atmospheric pressure or higher and thus bringing the jetted solution into collision in such a manner that water hammer is concentrated at the center of the cylinder on the same plane parallel to a cross-section in a radial direction of the cylinder.
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公开(公告)号：US20190298390A1
公开(公告)日：2019-10-03
申请号：US16352259
申请日：2019-03-13
Applicant: KAWASUMI LABORATORIES, INC. , Dai YAMANOUCHI
Inventor： Dai YAMANOUCHI , Takashi YOSHIMORI
IPC: A61B17/12
Abstract: A filler delivery device is configured to place a filler inside a bulge occurring in a body lumen. The filler delivery device includes a frame member configured to be expandable and compressible, and a tubular member through which a catheter for injecting the filler into the bulge is insertable. The tubular member is provided such that, when the frame member is in an expanded state, an open end of the tubular member is directed in a direction intersecting an extending direction of the body lumen. The filler material includes a base gel having flowability with which the filler material flows inside the catheter, and shape retainability with which the filler material stays inside the bulge after being injected from the catheter into the bulge, and a solidification promoting substance that promotes solidification of blood inside the bulge.
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Patent Agency Ranking
公开(公告)号：US20180353727A1
公开(公告)日：2018-12-13
申请号：US16005893
申请日：2018-06-12
Applicant: Dai Yamanouchi , KAWASUMI LABORATORIES, INC.
Inventor： Dai YAMANOUCHI , Akira Bonkohara
IPC: A61M25/00
CPC classification number: A61M25/0023 , A61M25/0068 , A61M25/0082 , A61M25/09 , A61M2025/0024 , A61M2025/0096
Abstract: A medical device is configured to treat a body cavity. The medical device includes a tubular sheath portion, a foreign substance capturing catheter configured to be movable inside the sheath portion, the foreign substance capturing catheter having a capturing portion configured to capture a foreign substance inside the body cavity, a treatment catheter configured to be movable inside the foreign substance capturing catheter, the treatment catheter having a treatment portion configured to treat the body cavity. The medical device is configured to be inserted into the body cavity in a state in which the treatment catheter is set inside the foreign substance capturing catheter and the foreign substance capturing catheter is set inside the sheath portion.
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公开(公告)号：US20180353280A1
公开(公告)日：2018-12-13
申请号：US16006259
申请日：2018-06-12
Applicant: Dai YAMANOUCHI
Inventor： Dai YAMANOUCHI
IPC: A61F2/01
CPC classification number: A61F2/013 , A61F2002/015 , A61F2002/016
Abstract: An infarction prevention device has a filter to be placed inside a blood vessel. The filter includes a connection portion having a base end to be connected to a placing member configured to place the filter inside the blood vessel, and a cylindrical body portion connected to a front end of the connection portion. At least one of the connection portion and the cylindrical body portion includes a capturing portion configured to capture a foreign substance included in blood inside the blood vessel such that the at least one of the connection portion and the body portion controls a flow of the foreign substance.
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公开(公告)号：US20200306026A1
公开(公告)日：2020-10-01
申请号：US16821284
申请日：2020-03-17
Applicant: Dai YAMANOUCHI , KAWASUMI LABORATORIES, INC.
Inventor： Dai YAMANOUCHI , Takashi Yoshimori
IPC: A61F2/01
Abstract: An infarction preventive device includes a cylindrical filter, a tube configured to hold a base end portion of the filter and place the filter in a blood vessel, and a recovery member configured to recover the filter placed in the blood vessel into the tube.
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公开(公告)号：US20190008550A1
公开(公告)日：2019-01-10
申请号：US16130516
申请日：2018-09-13
Applicant: Dai Yamanouchi , KAWASUMI LABORATORIES, INC.
Inventor： Dai YAMANOUCHI
IPC: A61B17/3207 , A61B17/221 , A61B17/22
Abstract: A capturing unit provided on a distal end of a second tube can be deformed into a contracted state and an expanded state, in which the capturing unit is deployed to form a capturing chamber. The capturing chamber has an opening area decreased as it goes from a distal end opening of the capturing chamber toward a proximal end opening of the capturing chamber. A third tube rotatable relative to the second tube and a cutting unit provided on a distal end of the third tube for cutting a foreign substance are arranged in a second lumen. In the expanded state of the capturing unit, the cutting unit is arranged more toward the proximal end opening of the capturing chamber than the distal end opening.
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公开(公告)号：US20150150589A1
公开(公告)日：2015-06-04
申请号：US14556827
申请日：2014-12-01
Applicant: Dai YAMANOUCHI , KAWASUMI LABORATORIES, INC.
Inventor： Dai YAMANOUCHI
IPC: A61B17/3207 , A61B17/221
CPC classification number: A61B17/320758 , A61B17/221 , A61B17/320725 , A61B17/32075 , A61B2017/22001 , A61B2017/22072 , A61B2017/22078 , A61B2017/22079 , A61B2017/2212 , A61B2017/2215 , A61B2017/320716 , A61B2017/320733 , A61B2017/320766 , A61B2017/320775 , A61B2217/005
Abstract: A capturing unit provided on a distal end of a second tube can be deformed into a contracted state and an expanded state, in which the capturing unit is deployed to form a capturing chamber. The capturing chamber has an opening area decreased as it goes from a distal end opening of the capturing chamber toward a proximal end opening of the capturing chamber. A third tube rotatable relative to the second tube and a cutting unit provided on a distal end of the third tube for cutting a foreign substance are arranged in a second lumen. In the expanded state of the capturing unit, the cutting unit is arranged more toward the proximal end opening of the capturing chamber than the distal end opening.
Abstract translation: 设置在第二管的远端的捕获单元可以变形为收缩状态和展开状态，其中捕获单元被展开以形成捕获室。 捕获室当从捕获室的远端开口朝向捕获室的近端开口时具有减小的开口面积。 相对于第二管可旋转的第三管和设置在第三管的远端用于切割异物的切割单元布置在第二管腔中。 在捕获单元的展开状态下，切割单元被布置成比远端开口更靠近捕获室的近端开口。
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