公开(公告)号：US11931562B2

公开(公告)日：2024-03-19

申请号：US17336017

申请日：2021-06-01

Applicant: Duke University

Inventor： Boyla Mainsah ,  Priyesh Patel ,  Leslie M. Collins ,  Ravi Karra ,  Emma LaPorte ,  Xinlin Chen

IPC: A61M60/00 ,  A61M60/178 ,  A61M60/216 ,  A61M60/515 ,  A61M60/538 ,  G10L21/0232 ,  G10L25/18 ,  G10L25/21 ,  G10L25/66 ,  G16H40/67

CPC classification number: A61M60/515 ,  A61M60/178 ,  A61M60/216 ,  A61M60/538 ,  G10L21/0232 ,  G10L25/18 ,  G10L25/21 ,  G10L25/66 ,  G16H40/67 ,  A61M2205/3365 ,  A61M2205/3375 ,  A61M2205/50 ,  A61M2230/04

Abstract: Disclosed are systems and techniques for determining an acoustic biomarker. For example, a precordial sound recording that includes at least a first sound component corresponding to a heart and a second sound component corresponding to a left ventricular assist device (LVAD) can be obtained. At least a portion of the second sound component corresponding to the LVAD can be filtered from the precordial sound recording to yield a filtered precordial sound recording. Based on the filtered precordial sound recording, at least one acoustic biomarker can be determined.

公开(公告)号：US20210370045A1

公开(公告)日：2021-12-02

申请号：US17336017

申请日：2021-06-01

Applicant: Duke University

Inventor： Boyla Mainsah ,  Priyesh Patel ,  Leslie M. Collins ,  Ravi Karra ,  Emma LaPorte ,  Xinlin Chen

IPC: A61M60/515 ,  G10L21/0232 ,  G10L25/66 ,  G10L25/21 ,  G10L25/18 ,  A61M60/178 ,  A61M60/538 ,  A61M60/216 ,  G16H40/67

Abstract: Disclosed are systems and techniques for determining an acoustic biomarker. For example, a precordial sound recording that includes at least a first sound component corresponding to a heart and a second sound component corresponding to a left ventricular assist device (LVAD) can be obtained. At least a portion of the second sound component corresponding to the LVAD can be filtered from the precordial sound recording to yield a filtered precordial sound recording. Based on the filtered precordial sound recording, at least one acoustic biomarker can be determined.

公开(公告)号：US20180140720A1

公开(公告)日：2018-05-24

申请号：US15461551

申请日：2017-03-17

Applicant: Duke University

Inventor： Kenneth D. Poss ,  Junsu Kang ,  Ravi Karra

IPC: A61K48/00 ,  C12N5/10 ,  C12N5/074 ,  C07K14/46 ,  C12N15/861 ,  A61P9/00

CPC classification number: A61K48/005 ,  A01K2217/20 ,  A61P9/00 ,  C07K14/461 ,  C12N5/0696 ,  C12N5/10 ,  C12N15/86 ,  C12N15/861 ,  C12N2015/8572 ,  C12N2320/10 ,  C12N2510/00 ,  C12N2750/14143 ,  C12N2800/106

Abstract: The present disclosure relates to compositions and methods for tissue regeneration.