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Patent Agency Ranking
公开(公告)号：US10406183B2
公开(公告)日：2019-09-10
申请号：US15425518
申请日：2017-02-06
Applicant: FUJIFILM Corporation
Inventor： Hayato Miyoshi , Ai Okamura , Ciara C. Tate , Monique A. Dao
IPC: A61K35/30 , C12N5/0797 , C12N5/079 , A61K38/39
Abstract: It is an object of the present invention to provide a cell-containing composition capable of suppressing the outflow of the cells after transplantation and improving the survival rate of the cells. The present invention provides a composition which comprises any of bone marrow stromal cell-derived neural precursor cells, bone marrow stromal cell-derived Schwann cells, or bone marrow stromal cell-derived skeletal muscle cells; and a biocompatible polymer.
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公开(公告)号：US11241518B2
公开(公告)日：2022-02-08
申请号：US16660003
申请日：2019-10-22
Applicant: FUJIFILM Corporation , JAPAN TISSUE ENGINEERING CO., LTD.
Inventor： Kentaro Nakamura , Hayato Miyoshi , Satoko Hada , Masatoki Watanabe
IPC: A61L27/36 , A61K38/39 , A61K35/28 , A61K38/17 , A61L27/22 , A61L27/38 , A61K35/32 , A61L27/54 , A61L27/56 , A61F2/30 , A61L27/58
Abstract: An object of the invention is to provide a cartilage regenerative material that is capable of regenerating bone and cartilage using cells. Provided is a cartilage regenerative material including a cell construct, which includes biocompatible polymer blocks and stem cells, in which a plurality of the biocompatible polymer blocks are disposed in gaps between a plurality of the stem cells.
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公开(公告)号：US11160902B2
公开(公告)日：2021-11-02
申请号：US15705669
申请日：2017-09-15
Applicant: FUJIFILM Corporation , JAPAN TISSUE ENGINEERING CO., LTD.
Inventor： Kentaro Nakamura , Hayato Miyoshi , Satoko Hada , Masatoki Watanabe
Abstract: An object of the invention is to provide a cartilage regenerative material that suppresses infiltration of fibrous soft tissue and brings about satisfactory cartilage regeneration, and a method for producing the cartilage regenerative material. Provided is a cartilage regenerative material including a porous body of a biocompatible polymer and a biocompatible polymer film, in which the porous body contains chondrocytes and cartilage matrix, and the cartilage matrix exists in a region of 10% or more of a region extending from the surface of the transplant face of the porous body to a depth of 150 μm along the thickness.
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公开(公告)号：US11453904B2
公开(公告)日：2022-09-27
申请号：US17693433
申请日：2022-03-14
Applicant: FUJIFILM CORPORATION
Inventor： Hayato Miyoshi , Takahiro Oba , Keisuke Oku
Abstract: There is provided an evaluation method for permeability of a porous membrane that separates a first flow channel and a second flow channel, the evaluation method including supplying a pressure to a liquid inside the first flow channel and acquiring a change that occurs in a liquid accommodated in the second flow channel as an evaluation indicator of permeability of the porous membrane.
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5.发明申请公开(公告)号：US20180361020A1
公开(公告)日：2018-12-20
申请号：US16118754
申请日：2018-08-31
Applicant: FUJIFILM Corporation
Inventor： Kentaro Nakamura , Reiko Iwazawa , Hayato Miyoshi , Kazuhiro Yamaguchi , Hideo Fushimi
Abstract: It is an object of the present invention to provide a cell construct for cell transplantation that does not contain a substance having cytotoxicity, such as glutaraldehyde, and suppresses the necrosis of the transplanted cells in the construct (namely, having a high cell survival rate). The present invention provides a cell construct for cell transplantation comprising biocompatible polymer blocks that do not contain glutaraldehyde and at least one type of cells, wherein a plurality of biocompatible polymer blocks are disposed in gaps among a plurality of cells, and wherein the biocompatible polymer blocks have a tap density of 10 mg/cm3 or more and 500 mg/cm3 or less, or the value of the square root of the cross-sectional area/boundary length in the two-dimensional sectional image of the polymer block is 0.01 or more and 0.13 or less.
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