公开(公告)号：US20180296604A1

公开(公告)日：2018-10-18

申请号：US15819654

申请日：2017-11-21

Applicant: FUKUOKA UNIVERSITY

Inventor： Shingo MIYAMOTO ,  Fusanori YOTSUMOTO

IPC: A61K35/28 ,  A61K35/44 ,  A61K47/36 ,  A61K9/00 ,  A61P15/08

Abstract: A pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes. The composition is administrated into an intrauterine cavity of a subject and used for treatment of infertility. A method for producing the pharmaceutical composition includes treating an adipose tissue with a disaggregation agent to obtain a disaggregated tissue; concentrating reproductive cells from the disaggregated tissue by centrifugal separation treatment; and recovering concentrated reproductive cells. A method for treatment of infertility of a subject includes administering a pharmaceutical composition into an intrauterine cavity of a subject. The pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes.

公开(公告)号：US20200078409A1

公开(公告)日：2020-03-12

申请号：US16684142

申请日：2019-11-14

Applicant: FUKUOKA UNIVERSITY

Inventor： Shingo MIYAMOTO ,  Fusanori YOTSUMOTO

IPC: A61K35/28 ,  A61K47/36 ,  A61K9/00 ,  A61P15/08 ,  A61K35/44 ,  A61K31/728

Abstract: A pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes. The composition is administrated into an intrauterine cavity of a subject and used for treatment of infertility. A method for producing the pharmaceutical composition includes treating an adipose tissue with a disaggregation agent to obtain a disaggregated tissue; concentrating reproductive cells from the disaggregated tissue by centrifugal separation treatment; and recovering concentrated reproductive cells. A method for treatment of infertility of a subject includes administering a pharmaceutical composition into an intrauterine cavity of a subject. The pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes.