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公开(公告)号：US12292417B2
公开(公告)日：2025-05-06
申请号：US18088471
申请日：2022-12-23
Applicant: Fukuoka University
Inventor： Masahiro Endo
Abstract: A repetitive moment generating device includes: eccentric weight members provided at shaft bodies in a state where the eccentric weight members intersect the rotatably held shaft bodies and in a state where the eccentric weight members are slidable in a direction that intersects the shaft bodies; sliders that are attached to the shaft bodies in a state where the sliders are slidable in a direction of shaft centers of the shaft bodies and in a state where the shaft bodies are able to idle; link mechanisms that convert sliding motion of the sliders in the directions of the shaft centers into sliding motion in a direction that intersects the shaft bodies and transmit the sliding motion to the eccentric weight members; handle that are operation means for causing the sliders to slide in the directions of the shaft centers of the shaft bodies; and the like.
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公开(公告)号：US20220176016A1
公开(公告)日：2022-06-09
申请号：US17599056
申请日：2020-03-27
Applicant: NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY , SHINSHU UNIVERSITY , FUKUOKA UNIVERSITY
Inventor： Takumi Okihara , Yoshiki Takada , Naoto Saito , Kaoru Aoki , Naoyuki Nishimura , Hisao Haniu , Shigeaki Moriyama , Katsuya Ueda
Abstract: The present invention addresses the problem of providing, by a method in which an expensive manufacturing apparatus is not required, an implant material having osteoconductivity superior to that of an implant material containing an aromatic polyether ketone. The present invention pertains to: said method including immersing an aromatic polyether ketone in a strong base solution in the absence of a calcium ion, and immersing an aromatic polyether ketone, which is obtained by the immersing, in a liquid containing a phosphorus-containing compound; and an implant material obtained by said method.
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公开(公告)号：US10959960B2
公开(公告)日：2021-03-30
申请号：US15565104
申请日：2016-04-07
Applicant: SonoCore, Inc. , Fukuoka University
Inventor： Katsuro Tachibana
IPC: A61B8/06 , A61J1/14 , B65B3/00 , B65D51/00 , A61K9/50 , A61K49/00 , B01F11/00 , B01F3/04 , A61K49/22 , A61N7/00 , A61K47/02 , A61K47/12 , A61K47/24 , A61K47/26 , A61K47/42 , A61K9/127 , A61K9/10 , A61K47/28
Abstract: A bubble manufacturing container 20 of the present invention includes: a container body 21 having an opening portion; and a rubber stopper 221 provided on the opening portion of the container body 21. The rubber stopper 221 is constituted so that the bubbles 1 of an inside of the container body 21 are able to be taken by piercing an injection needle. It is preferred that the bubble manufacturing container 20 has a fastening portion 222 provided on the rubber stopper 221, having an opening and sealing the container body 21 with the rubber stopper 221. Furthermore, it is preferred that the container body 21 mounts a weight portion.
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4.发明申请公开(公告)号：US20200078409A1
公开(公告)日：2020-03-12
申请号：US16684142
申请日：2019-11-14
Applicant: FUKUOKA UNIVERSITY
Inventor： Shingo MIYAMOTO , Fusanori YOTSUMOTO
Abstract: A pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes. The composition is administrated into an intrauterine cavity of a subject and used for treatment of infertility. A method for producing the pharmaceutical composition includes treating an adipose tissue with a disaggregation agent to obtain a disaggregated tissue; concentrating reproductive cells from the disaggregated tissue by centrifugal separation treatment; and recovering concentrated reproductive cells. A method for treatment of infertility of a subject includes administering a pharmaceutical composition into an intrauterine cavity of a subject. The pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes.
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5.发明申请ULTRASOUND-GUIDED PUNCTURE ASSIST DEVICE AND ULTRASOUND-GUIDED PUNCTURE METHOD USING THE SAME 审中-公开超声波引导式辅助装置和超声波引导方法公开(公告)号：US20160051279A1
公开(公告)日：2016-02-25
申请号：US14780250
申请日：2014-03-27
Applicant: FUKUOKA UNIVERSITY
Inventor： Isao HARAGA , Kazuo HIGA , Keiichi NITAHARA
CPC classification number: A61B17/3403 , A61B8/0841 , A61B8/0891 , A61B8/42 , A61B8/4444 , A61B17/3401 , A61B2017/00349 , A61B2017/306 , A61B2017/3413
Abstract: [Problem]Provided are: an ultrasound-guided puncture assist device that is capable of preventing occurrence of operational mistakes or the like when a nerve block or vascular puncture is performed under ultrasonography, an ultrasound-guided puncture method using the ultrasound-guided puncture assist device, and the like.[Solution]An ultrasound-guided puncture assist device with an object of preventing narrowing or the like of a puncture target site for a nerve block or vascular puncture under ultrasonography to thereby assist the puncture by comprising a pulling mechanism for pulling the surface of the puncture target site, such as skin. The use of the ultrasound-guided puncture assist device of the invention can increase the width of the target site tissue where a nerve block or vascular puncture is performed, and thus occurrence of mispuncture is preventable.
Abstract translation: [问题]提供一种超声波引导穿刺辅助装置，其能够在超声波下进行神经阻滞或血管穿刺时能够防止发生操作错误等，超声波引导穿刺法使用超声波引导穿刺辅助 装置等。 【解决方案】超声波引导穿刺辅助装置，其特征在于，在超声波检查下，可以防止穿刺目的部位用于神经阻滞或血管穿刺的变窄等，从而通过包括用于拉动穿刺表面的牵引机构来辅助穿刺 目标网站，如皮肤。 本发明的超声波引导穿刺辅助装置的使用可以增加进行神经阻滞或血管穿刺的靶部位组织的宽度，能够防止误穿的发生。
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Patent Agency Ranking
公开(公告)号：US12158451B2
公开(公告)日：2024-12-03
申请号：US17961773
申请日：2022-10-07
Applicant: Fukuoka University
Inventor： Masahiro Endo
Abstract: Provided is a repeated moment generation device that includes: a principal shaft; principal bearing members; lever members; principal eccentric weight rotors; auxiliary eccentric weight rotors; and drive means (such as a motor) for causing the principal eccentric weight rotors and the auxiliary eccentric weight rotors to synchronously rotate. Eccentricity directions of the principal eccentric weight rotors are different from each other by 180 degrees around shaft centers of shaft bodies thereof, eccentricity directions of the auxiliary eccentric weight rotors are different from each other by 180 degrees around shaft centers of shaft bodies thereof, and the eccentricity direction of the principal eccentric weight rotor and the eccentricity direction of the auxiliary weight rotor located on the same side as the principal eccentric weight rotor with respect to the principal shaft 1 are different from each other by 180 degrees around the shaft centers of the shaft bodies thereof.
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7.发明公开公开(公告)号：US20230265431A1
公开(公告)日：2023-08-24
申请号：US18187880
申请日：2023-03-22
Applicant: FUKUOKA UNIVERSITY , DAIICHI SANKYO COMPANY, LIMITED
Inventor： Masatora FUKUDA
IPC: C12N15/113
CPC classification number: C12N15/113 , C12N2310/531
Abstract: Provided is a short-chain guide RNA that is able to induce site-specific editing even when only a small number of nucleotides is attached to the target recognition site. The guide RNA includes a first oligonucleotide that identifies the target RNA, and a second oligonucleotide that links to the 3′ end of the first oligonucleotide. The first oligonucleotide contains: a target-corresponding nucleotide residue that corresponds to an adenosine residue in the target RNA; an oligonucleotide of 15 to 30 residues that links to the 5′ end of the target-corresponding nucleotide residue and that has a base sequence complementary to the target RNA; and an oligonucleotide of 3 or 4 residues that links to the 3′ end of the target-corresponding nucleotide residue and that has a base sequence complementary to the target RNA. The second oligonucleotide contains 2 to 24 nucleotide residues, and induces site-specific editing of the target RNA.
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公开(公告)号：US20230166229A1
公开(公告)日：2023-06-01
申请号：US17922607
申请日：2021-05-13
Applicant: FUKUOKA UNIVERSITY
Inventor： KENJI MISHIMA , SHINICHI TOKUNAGA , KENTO ONO
IPC: B01J13/08
CPC classification number: B01J13/08
Abstract: A method for producing a cellulose nanofiber capsule according to the present invention includes forming a Pickering emulsion by irradiating a mixture containing cellulose nanofibers, water, and fluid carbon dioxide with ultrasonic waves in a closed container; and facilitating encapsulation using cellulose nanofibers from the Pickering emulsion by opening the closed container. The present invention enables encapsulation using the cellulose nanofibers from a Pickering emulsion that does not contain an organic solvent, for example, and is useful in the technical fields of pharmaceutical agents, foods, and cosmetics, for example.
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9.发明授权公开(公告)号：US11643658B2
公开(公告)日：2023-05-09
申请号：US16770161
申请日：2018-12-05
Applicant: FUKUOKA UNIVERSITY , DAIICHI SANKYO COMPANY, LIMITED
Inventor： Masatora Fukuda
IPC: C12N15/113
CPC classification number: C12N15/113 , C12N2310/531
Abstract: Provided is a short-chain guide RNA that is able to induce site-specific editing even when only a small number of nucleotides is attached to the target recognition site. The guide RNA includes a first oligonucleotide that identifies the target RNA, and a second oligonucleotide that links to the 3′ end of the first oligonucleotide. The first oligonucleotide contains: a target-corresponding nucleotide residue that corresponds to an adenosine residue in the target RNA; an oligonucleotide of 15 to 30 residues that links to the 5′ end of the target-corresponding nucleotide residue and that has a base sequence complementary to the target RNA; and an oligonucleotide of 3 or 4 residues that links to the 3′ end of the target-corresponding nucleotide residue and that has a base sequence complementary to the target RNA. The second oligonucleotide contains 2 to 24 nucleotide residues, and induces site-specific editing of the target RNA.
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10.发明申请公开(公告)号：US20180296604A1
公开(公告)日：2018-10-18
申请号：US15819654
申请日：2017-11-21
Applicant: FUKUOKA UNIVERSITY
Inventor： Shingo MIYAMOTO , Fusanori YOTSUMOTO
Abstract: A pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes. The composition is administrated into an intrauterine cavity of a subject and used for treatment of infertility. A method for producing the pharmaceutical composition includes treating an adipose tissue with a disaggregation agent to obtain a disaggregated tissue; concentrating reproductive cells from the disaggregated tissue by centrifugal separation treatment; and recovering concentrated reproductive cells. A method for treatment of infertility of a subject includes administering a pharmaceutical composition into an intrauterine cavity of a subject. The pharmaceutical composition contains adipose tissue derived reproductive cells including adipose stem cells, vascular endothelial cells and vascular pericytes.
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