公开(公告)号：US3839204A

公开(公告)日：1974-10-01

申请号：US24798772

申请日：1972-04-27

Applicant: GEN ELECTRIC

Inventor： INGENITO D ,  MATHEWSON W ,  RYON D ,  WALMET G

IPC: A61M1/22 ,  B01D63/08 ,  B01D13/00

CPC classification number: B01D61/28 ,  B01D63/08 ,  B01D2313/38 ,  B01D2325/08

Abstract: A device for oxygenating or dialyzing blood has elementary units comprising a heat exchanger close-coupled to a component exchanger comprising one or more frames having rectangular openings and a gas permeable membrane on each face. In the heat exchanger element, heat is transferred via conduction from a source or to a sink through a membrane to or from a flowing film of blood. Two confronting membranes define a thin passageway for blood in the component exchanger element and remote sides of the membranes confront a second passageway in which another fluid such as dialysate or oxygen enriched gas flows, the passageway containing an open support structure. The support structure distributes the gas uniformly and supports the membranes when the space between them is pressurized with blood. In preferred embodiments, there are provided two path thin film flows through the heat exchanger. In the gas exchanger, thermoplastically formed protuberances project integrally from the membranes into the blood space for precisely defining the blood film thickness. Also provided is a blood component exchanger including an open support structure shaped to provide two path thin film flows therethrough.

Abstract translation: 用于氧化或透析血液的装置具有基本单元，其包括紧密耦合到部件交换器的热交换器，该部件交换器包括具有矩形开口的一个或多个框架和每个面上的透气膜。 在热交换器元件中，热量通过从源或通过膜通过膜传导到或流过血液膜而传递。 两个相对的膜在组件交换器元件中限定用于血液的薄通道，并且膜的远侧面对第二通道，其中另一种流体例如透析液或富氧气体流动，该通道包含开放的支撑结构。 支撑结构均匀地分布气体，并且当它们之间的空间用血液加压时支撑膜。 在优选实施例中，提供了穿过热交换器的两条路径薄膜流。 在气体交换器中，热塑性形成的突起从膜整体突出到血液空间中，以精确地限定血液膜厚度。 还提供了一种血液成分交换器，其包括形状为提供穿过其中的两条路径薄膜流动的开放支撑结构。

公开(公告)号：US3724673A

公开(公告)日：1973-04-03

申请号：US3724673D

申请日：1970-08-28

Applicant: GEN ELECTRIC

Inventor： RYON D

IPC: A61M1/00 ,  A61M1/22 ,  B01D63/08 ,  B29C51/10 ,  B29C51/18 ,  B01D31/00

CPC classification number: B01D71/80 ,  B01D71/50 ,  B01D71/70 ,  B01D71/76 ,  B01D2325/06

Abstract: A myriad of small undulations or projections are formed permanently in a thin membrane to give it a textured surface. The membrane may be permselective for use in fluid exchange devices such as blood oxygenators and artificial kidneys or dialyzers. When such membranes are superposed on each other, a thin film of blood or other fluid flowing between them is gently agitated by the textured surface to enhance the absorption of a gas such as oxygen which is transported through the membrane. The textured surface prevents adjacent membrane layers from adhering. The textured surface is created by heating, vacuum forming and cooling on a suitable die.

Abstract translation: 许多小的起伏或突起永久地形成在薄膜中，以赋予其纹理表面。 膜可以是选择性选择性的，用于流体交换装置，例如血液充氧器和人造肾或透析器。 当这样的膜彼此重叠时，由纹理表面轻轻搅动血液或其间流动的其它流体的薄膜，以增强通过膜输送的气体（例如氧气）的吸收。 纹理表面防止相邻的膜层粘附。 纹理表面通过加热，真空成型和在合适的模具上冷却而产生。