公开(公告)号：US20170050907A1

公开(公告)日：2017-02-23

申请号：US14903337

申请日：2014-07-23

Applicant: HARRIS CORPORATION

Inventor： Michael J. Stone ,  Howard W. Brooks ,  Heinz Strutz ,  Donald K. Raff ,  Guido D. Frey ,  Norman Nowotny ,  Marcos Schroeder ,  Fred Gaytan ,  Tracy Kevin Hunt ,  William E. Slinkard

IPC: C07C29/38 ,  B01J19/24 ,  B01J8/06

CPC classification number: C07C29/38 ,  B01J8/04 ,  B01J8/065 ,  B01J8/067 ,  B01J19/242 ,  B01J2208/00061 ,  B01J2208/00106 ,  B01J2208/0053 ,  B01J2208/02 ,  C07C31/20

Abstract: A multistage tubular reaction system and method for preparing methylol derivatives of an aldehyde includes a tubular reaction system with a plurality of successive reactor stages comprising a plurality of jacketed reaction tubes provided with a cooling system adapted to control flow of a cooling medium through said jacketed reaction tubes. The cooling medium flow is controlled independently in different stages in response to temperature measurements in the reaction system to regulate temperature. In order to further reduce temperature spikes and byproduct generation, aldehyde is stepwise added to the production stream at a plurality of feed ports proximate to reaction tubes equipped with tube inserts to enhance mixing and heat transfer.

Abstract translation: 用于制备醛的羟甲基衍生物的多级管状反应体系和方法包括具有多个连续反应器阶段的管状反应体系，其包含多个夹套反应管，其具有适于控制冷却介质通过所述夹套反应的流动的冷却系统 管。 响应于反应体系中的温度测量来调节温度，冷却介质流在不同阶段独立地控制。 为了进一步降低温度峰值和副产物的产生，醛在靠近配有管插入件的反应管的多个进料口处逐步添加到生产流中以增强混合和热传递。