公开(公告)号：US20250090822A1

公开(公告)日：2025-03-20

申请号：US18292103

申请日：2022-08-19

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Tetsuji KUWAHARA ,  Keiichiro TSURUSHIMA ,  Masafumi ONO ,  Masato WAKAMATSU ,  Tetsuro TATEISHI

IPC: A61M37/00 ,  A61K9/00 ,  A61K47/32

Abstract: A microneedle patch according to one example includes a backing, an adhesive layer provided on the main surface of the backing, and a microneedle array at least a part of which is positioned within the adhesive layer, wherein the adhesive layer includes a water-soluble polymer and water, and a loss tangent of the adhesive layer under measurement conditions of an environmental temperature of 25° C. and a frequency of 1 Hz is 0.20 to 0.41.

公开(公告)号：US20190381300A1

公开(公告)日：2019-12-19

申请号：US16488450

申请日：2018-02-20

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Toru KOBAYASHI ,  Toshiyuki MATSUDO ,  Shinpei NISHIMURA ,  Seiji TOKUMOTO ,  Tetsuji KUWAHARA

IPC: A61M37/00

Abstract: A method for producing a microneedle device having a coating on the microneedles comprises a step A of drying a precursor composition containing a biologically active substance and a first solvent to obtain -a freeze-dried composition, a step B of mixing the freeze-dried composition with a second solvent to obtain a coating composition, and a step C of applying the coating composition to the microneedles and drying the same, wherein the precursor composition further contains a thickener, or a thickener is added when the freeze-dried composition and the second solvent are mixed.