公开(公告)号：US3817628A

公开(公告)日：1974-06-18

申请号：US28135672

申请日：1972-08-17

Applicant: HOFFMANN LA ROCHE

Inventor： ADAMS J

IPC: G01J3/427 ,  G01N21/27 ,  G01N21/47 ,  G01N21/48

CPC classification number: G01N21/474

Abstract: A method and apparatus for analyzing visible reflectance data of a granular crystalline powder sample in a solid state relative to reflectance data for a reference specimen, by minimizing the effects of the powder particle size on the measurement of the sample optical properties comprising, an optical assembly for deriving sample reference reflectance data, effecting standardization of the sample reflectance data relative to the reference reflectance data by a ratio comparison, and processing the standardized signals effected to establish an output indicator signal representative of the sample optical properties for ascertaining the degrees of presence/absence of the optical quality to be measured.

Abstract translation: 一种用于通过使粉末粒度对样品光学性质的测量的影响最小化而分析相对于参考样品的反射率数据而言，固态颗粒状结晶性粉末样品的可见光反射率数据的方法和装置，包括：光学组件 用于导出样本参考反射率数据，通过比率比较来实现样本反射率数据相对于参考反射率数据的标准化，并且处理所形成的标准化信号，以建立表示样本光学性质的输出指示符信号，以确定存在/ 没有要测量的光学质量。

公开(公告)号：US3760166A

公开(公告)日：1973-09-18

申请号：US3760166D

申请日：1971-12-08

Applicant: HOFFMANN LA ROCHE

Inventor： ADAMS J ,  GRIMMELL W

IPC: G06M1/10 ,  G06M1/272

CPC classification number: G06M1/101

Abstract: A highly accurate counting technique for large numbers of randomly flowing, discrete solid particular sample materials such as capsules utilizing a feeder-sensor assembly and associated circuitry is described. The feeder-sensor assembly employs a pressure gradient along the sample passageway induced by a highvelocity air jet below the sensing element to effectuate proper spacing of the sample so that the sensing element can register individual passage of the samples. A secondary air flow which assists in sample separation is provided by employing an air space between the sample imput cavity and the sensor element position of the feeder sensor assembly. In a preferred embodiment the output of a plurality of feeder-sensor assemblies is fed to discrete channels into a counter circuit distinguished in having the memory latch reset controlled by a delayed multiplexer pulse synchronized to the address counter output. Thus, a reset pulse is supplied to the memory latch only if it were previously set.

Abstract translation: 描述了用于大量随机流动的离散固体特定样品材料（例如使用馈线 - 传感器组件和相关电路的胶囊）的高精度计数技术。 馈送器 - 传感器组件采用沿着样品通道的压力梯度，由感测元件下方的高速空气射流引起，以实现样品的适当间隔，使得感测元件可以记录样品的单独通道。 通过在样品输入腔和馈送器传感器组件的传感器元件位置之间采用空气空间来提供辅助样品分离的二次空气流。 在优选实施例中，多个馈送器 - 传感器组件的输出被馈送到分立的通道中，其特征在于具有与地址计数器输出同步的延迟复用器脉冲控制的存储器锁存复位。 因此，只有在先前设置的情况下，才将复位脉冲提供给存储器锁存器。

公开(公告)号：US3737239A

公开(公告)日：1973-06-05

申请号：US3737239D

申请日：1971-07-16

Applicant: HOFFMANN LA ROCHE

Inventor： ADAMS J ,  GRIMMELL W

IPC: G01J3/46

CPC classification number: G01J3/46 ,  G01J3/513

Abstract: Automatic cross-correlation specimen monitoring apparatus and method for identifying spectral reflectance characteristics of a specimen relative to a standard comprising: sensing reflectance values of the specimen at each of two or more overlapping bandwidths covering the spectrum, generating electrical output signals indicative of the reflectance values, modifying the signals with standard reference values one for each of the bandwidths, relating the modified and unmodified signals to generate a cross-correlation coefficient between the specimen reflectance values and the standard reference values, and comparing the cross-correlation coefficient with a preset value representative of a minimum deviation from the standard to quantitatively determine the similarity in spectral reflectance between the specimen and the standard.

Abstract translation: 用于识别样本相对于标准的光谱反射率特性的自动互相关样本监测装置和方法，包括：在覆盖该光谱的两个或更多个重叠带宽中的每一个处检测样本的反射率值，产生指示反射率值的电输出信号 对每个带宽修改一个标准参考值的信号，将修改和未修改的信号相关联，以产生样本反射率值和标准参考值之间的互相关系数，并将互相关系数与预设值进行比较 代表与标准的最小偏差，以定量确定样品与标准品之间的光谱反射率的相似性。