公开(公告)号：US10343986B2

公开(公告)日：2019-07-09

申请号：US16133146

申请日：2018-09-17

Applicant: Haldor Topsoe A/S

Inventor： Irantzu Sadaba Zubiri ,  Esben Taarning

IPC: C07C319/18 ,  C07C67/44 ,  C07C67/475 ,  C07C67/00 ,  C07C69/68 ,  C07C69/732

Abstract: A continuous flow process for the preparation of one or more esters of lactic acid and 2-hydroxy-3-butenoic acid or α-hydroxy methionine analogs from a sugar in the presence of a solid Lewis acid catalyst and a solvent comprising an organic solvent and water. The invention facilitates Lewis acid catalyst stability in a continuous reaction process where the water is present in an amount of up to or equal to 10 vol. % of the organic solvent.

公开(公告)号：US20190016674A1

公开(公告)日：2019-01-17

申请号：US16133146

申请日：2018-09-17

Applicant: Haldor Topsoe A/S

Inventor： Irantzu Sadaba Zubiri ,  Esben Taarning

IPC: C07C319/18 ,  C07C67/475 ,  C07C69/68 ,  C07C69/732 ,  C07C67/00 ,  C07C67/44 ,  C07C323/58

CPC classification number: C07C319/18 ,  C07C67/00 ,  C07C67/44 ,  C07C67/475 ,  C07C69/68 ,  C07C69/732 ,  C07C323/58

Abstract: A continuous flow process for the preparation of one or more esters of lactic acid and 2-hydroxy-3-butenoic acid or α-hydroxy methionine analogues from a sugar in the presence of a solid Lewis acid catalyst and a solvent comprising an organic solvent and water. The invention provides a means for stabilizing a Lewis acid catalyst for use in a continuous reaction process wherein the water is present in an amount of up to or equal to 10 vol. % of the organic solvent.

公开(公告)号：US10280136B2

公开(公告)日：2019-05-07

申请号：US16133100

申请日：2018-09-17

Applicant: Haldor Topsoe A/S

Inventor： Irantzu Sadaba Zubiri ,  Esben Taarning

IPC: C07C319/18 ,  C07C69/68 ,  C07C69/732 ,  C07C67/00 ,  C07C67/44 ,  C07C67/475

Abstract: A continuous flow process for the preparation of one or more esters of lactic acid and 2-hydroxy-3-butenoic acid or α-hydroxy methionine analogs from a sugar in the presence of a solid Lewis acid catalyst and a solvent comprising an organic solvent and water. The invention provides a stabilized Lewis acid catalyst for use in a continuous reaction process, where the water is present in an amount of up to or equal to 10 vol. % of the organic solvent.

公开(公告)号：US20190062271A1

公开(公告)日：2019-02-28

申请号：US16133100

申请日：2018-09-17

Applicant: Haldor Topsoe A/S

Inventor： Irantzu Sadaba Zubiri ,  Esben Taarning

IPC: C07C319/18 ,  C07C67/475 ,  C07C69/68 ,  C07C69/732 ,  C07C67/00 ,  C07C67/44 ,  C07C323/58

Abstract: A continuous flow process for the preparation of one or more esters of lactic acid and 2-hydroxy-3-butenoic acid or α-hydroxy methionine analogues from a sugar in the presence of a solid Lewis acid catalyst and a solvent comprising an organic solvent and water. The invention provides a means for stabilizing a Lewis acid catalyst for use in a continuous reaction process wherein the water is present in an amount of up to or equal to 10 vol. % of the organic solvent.

公开(公告)号：US09975113B2

公开(公告)日：2018-05-22

申请号：US15435758

申请日：2017-02-17

Applicant: Haldor Topsoe A/S

Inventor： Martin Spangsberg Holm ,  Irantzu Sadaba Zubiri ,  Søren Tolborg ,  Christian Mårup Osmundsen ,  Esben Taarning

IPC: C07C69/66 ,  B01J29/70 ,  C07C67/00 ,  B01J29/08 ,  B01J37/04 ,  B01J37/08 ,  B01J37/10

CPC classification number: B01J29/7057 ,  B01J29/088 ,  B01J29/7049 ,  B01J37/04 ,  B01J37/08 ,  B01J37/10 ,  B01J2229/16 ,  C07C67/00 ,  Y02P20/582 ,  C07C69/68

Abstract: A process for the preparation of lactic acid and 2-hydroxy-3-butenoic acid or esters thereof from a sugar in the presence of a metallo-silicate material, a metal ion and a solvent, wherein the metal ion is selected from one or more of the group consisting of potassium ions, sodium ions, lithium ions, rubidium ions and caesium ions.

公开(公告)号：US20170173570A1

公开(公告)日：2017-06-22

申请号：US15435758

申请日：2017-02-17

Applicant: Haldor Topsoe A/S

Inventor： Martin Spangsberg Holm ,  lrantzu Sadaba Zubiri ,  Søren Tolborg ,  Christian Mårup Osmundsen ,  Esben Taarning

IPC: B01J29/70 ,  B01J37/08 ,  B01J37/04 ,  B01J37/10 ,  C07C67/00 ,  B01J29/08

CPC classification number: B01J29/7057 ,  B01J29/088 ,  B01J29/7049 ,  B01J37/04 ,  B01J37/08 ,  B01J37/10 ,  B01J2229/16 ,  C07C67/00 ,  Y02P20/582 ,  C07C69/68

Abstract: A process for the preparation of lactic acid and 2-hydroxy-3-butenoic acid or esters thereof from a sugar in the presence of a metallo-silicate material, a metal ion and a solvent, wherein the metal ion is selected from one or more of the group consisting of potassium ions, sodium ions, lithium ions, rubidium ions and caesium ions.