公开(公告)号：US09433714B2

公开(公告)日：2016-09-06

申请号：US14405948

申请日：2013-06-06

Applicant: HeartWare, Inc.

Inventor： Neil Voskoboynikov ,  Joel Graham

IPC: A61N1/362 ,  A61M1/10 ,  G06F19/00

CPC classification number: A61M1/1086 ,  A61M1/101 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2205/3365 ,  G06F19/00 ,  G16H40/63

Abstract: A ventricular assist device (“VAD”) includes a continuous-flow pump (2) implantable in fluid communication with a ventricle (V) and an artery (A) of a patient to assist blood flow from the ventricle to the artery. The VAD also includes a control circuit (12) connected to the pump, the control circuit being configured to direct the pump to operate in a series of cycles. Each cycle may include (i) pumping blood at a first speed (RPM1) and at a first flow rate during a first period (t1); then (ii) decreasing the speed of the pump from the first speed to a second speed (RPM2) during a ramp-down period (tRD); then (iii) pumping blood at the second speed and at a second flow rate during a second period (t2); and then (iv) increasing the speed of the pump from the second speed to the first speed during a ramp-up period (tRU).

Abstract translation: 心室辅助装置（“VAD”）包括可植入与患者的心室（V）和动脉（A）流体连通的连续流动泵（2），以辅助血液从心室流到动脉。 VAD还包括连接到泵的控制电路（12），所述控制电路被配置为引导泵以一系列循环操作。 每个循环可以包括（i）在第一时间段（t1）期间以第一速度（RPM1）和第一流量泵送血液; 然后（ii）在减速期（tRD）期间将泵的速度从第一速度降低到第二速度（RPM2）; 然后（iii）在第二时段（t2）期间以第二速度和第二流量泵血; 然后（iv）在升温期（tRU）期间将泵的速度从第二速度增加到第一速度。

公开(公告)号：US09656011B2

公开(公告)日：2017-05-23

申请号：US14799703

申请日：2015-07-15

Applicant: HeartWare, Inc.

Inventor： Joel Graham ,  Charles R. Shambaugh

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/122 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/125 ,  A61M2205/04 ,  A61M2210/125

Abstract: A method of implanting a blood pump in a heart of a mammalian subject includes maintaining a temporary plug in an inlet opening of a pump having a pump body and an outlet cannula projecting from the pump body, advancing the pump into a ventricle of the heart through a hole in a wall of the heart so that the inlet of the pump is disposed within the ventricle and the outlet cannula extends through a valve of the heart into an artery, and then withdrawing the temporary plug from the inlet of the pump.

公开(公告)号：US10328190B2

公开(公告)日：2019-06-25

申请号：US15497670

申请日：2017-04-26

Applicant: HeartWare, Inc.

Inventor： Joel Graham ,  Charles R. Shambaugh

IPC: A61M1/12 ,  A61M1/10

Abstract: A method of implanting a blood pump in a heart of a mammalian subject includes maintaining a temporary plug in an inlet opening of a pump having a pump body and an outlet cannula projecting from the pump body, advancing the pump into a ventricle of the heart through a hole in a wall of the heart so that the inlet of the pump is disposed within the ventricle and the outlet cannula extends through a valve of the heart into an artery, and then withdrawing the temporary plug from the inlet of the pump.

公开(公告)号：US20160015878A1

公开(公告)日：2016-01-21

申请号：US14799703

申请日：2015-07-15

Applicant: HeartWare, Inc.

Inventor： Joel Graham ,  Charles R. Shambaugh

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/122 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/125 ,  A61M2205/04 ,  A61M2210/125

Abstract: A method of implanting a blood pump in a heart of a mammalian subject includes maintaining a temporary plug in an inlet opening of a pump having a pump body and an outlet cannula projecting from the pump body, advancing the pump into a ventricle of the heart through a hole in a wall of the heart so that the inlet of the pump is disposed within the ventricle and the outlet cannula extends through a valve of the heart into an artery, and then withdrawing the temporary plug from the inlet of the pump.

Abstract translation: 在哺乳动物对象的心脏中植入血液泵的方法包括：将具有泵体的泵的入口开口中的临时塞子保持在泵主体突出的出口套管上，将泵推入心脏心室的心室 在心脏壁上的孔，使得泵的入口设置在心室内，并且出口插管延伸穿过心脏的瓣膜进入动脉，然后从泵的入口抽出临时塞子。