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公开(公告)号：US12102814B2
公开(公告)日：2024-10-01
申请号：US17193548
申请日：2021-03-05
Applicant: HeartWare, Inc.
Inventor： Michael C. Brown , Veronica Ramos , Neil Voskoboynikov
IPC: A61M60/122 , A61B5/0215 , A61M5/142 , A61M60/126 , A61M60/538 , A61M60/585 , A61M60/592 , A61B5/00
CPC classification number: A61M60/538 , A61M5/1428 , A61M60/126 , A61M60/585 , A61M60/592 , A61B5/0031 , A61B5/0215 , A61B5/686 , A61M2205/3334
Abstract: A method of determining a presence of suction in a patient having an implantable blood pump from down-sampled log files. The method comprising calculating a waveform index for each of a plurality of flow rate data points from the down-sampled log files. The calculated waveform index is compared with a predetermined waveform index threshold. A non-suction trough baseline is calculated from the plurality of flow rate data points. A difference between a measured trough and a calculated non-suction trough baseline is compared with a predetermined threshold. The presence of suction for each of the plurality of flow rate data points is determined if the calculated waveform index is greater than the predetermined waveform index threshold and the difference between the measured trough and a calculated non-suction trough baseline is greater than the predetermined threshold.
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公开(公告)号：US09433714B2
公开(公告)日：2016-09-06
申请号：US14405948
申请日：2013-06-06
Applicant: HeartWare, Inc.
Inventor： Neil Voskoboynikov , Joel Graham
CPC classification number: A61M1/1086 , A61M1/101 , A61M1/122 , A61M2205/3334 , A61M2205/3365 , G06F19/00 , G16H40/63
Abstract: A ventricular assist device (“VAD”) includes a continuous-flow pump (2) implantable in fluid communication with a ventricle (V) and an artery (A) of a patient to assist blood flow from the ventricle to the artery. The VAD also includes a control circuit (12) connected to the pump, the control circuit being configured to direct the pump to operate in a series of cycles. Each cycle may include (i) pumping blood at a first speed (RPM1) and at a first flow rate during a first period (t1); then (ii) decreasing the speed of the pump from the first speed to a second speed (RPM2) during a ramp-down period (tRD); then (iii) pumping blood at the second speed and at a second flow rate during a second period (t2); and then (iv) increasing the speed of the pump from the second speed to the first speed during a ramp-up period (tRU).
Abstract translation: 心室辅助装置（“VAD”）包括可植入与患者的心室（V）和动脉（A）流体连通的连续流动泵（2），以辅助血液从心室流到动脉。 VAD还包括连接到泵的控制电路（12），所述控制电路被配置为引导泵以一系列循环操作。 每个循环可以包括（i）在第一时间段（t1）期间以第一速度（RPM1）和第一流量泵送血液; 然后（ii）在减速期（tRD）期间将泵的速度从第一速度降低到第二速度（RPM2）; 然后（iii）在第二时段（t2）期间以第二速度和第二流量泵血; 然后（iv）在升温期（tRU）期间将泵的速度从第二速度增加到第一速度。
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公开(公告)号：US10856804B2
公开(公告)日：2020-12-08
申请号：US16026760
申请日：2018-07-03
Applicant: HeartWare, Inc.
Inventor： Neil Voskoboynikov , Veronica Ramos
Abstract: A method determining adverse events from operation of an implantable blood pump including calculating a moving average convergence divergence (MACD) based on power consumed by the implantable blood pump to maintain a constant rotational speed of an impeller of the implantable blood pump. An alert is generated when the calculated MACD diverges from a predetermined MACD threshold and a predetermined MACD zero-crossing time threshold.
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公开(公告)号：US10675396B2
公开(公告)日：2020-06-09
申请号：US15665718
申请日：2017-08-01
Applicant: HeartWare, Inc.
Inventor： Michael C. Brown , Neil Voskoboynikov
Abstract: A method of detecting a suction condition during operation of a rotary blood pump with an inlet connected to a ventricle of the heart of a patient, an outlet connected to an artery of the patient, a rotor, and a control circuit configured maintain the rotor at a set rotational speed. The method includes measuring the rotational speed of the rotor at a plurality of times during each of a plurality of speed measurement intervals. A speed range is determined between a minimum measured speed and a maximum measured speed during each of the plurality of speed measurement intervals. At least one additional parameter relating to the operation of the blood pump is derived. A suction detection signal is generated if both at least one determined speed range is above a speed range limit and the at least one additional parameter is indicative of a suction condition.
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公开(公告)号：US10434234B2
公开(公告)日：2019-10-08
申请号：US15717105
申请日：2017-09-27
Applicant: HeartWare, Inc.
Inventor： Michael C. Brown , Neil Voskoboynikov
Abstract: The present disclosure provides for a method, control device, and implantable system, for acquiring a plurality of flow rate data points over time, each data point indicative of a flow rate of blood through the pump, calculating, based on the plurality of acquired flow rate data points, a value characterizing one or more features of a waveform formed from the plurality of flow rate data points; and determining, based on the value, the presence or absence of a suction condition in the pump.
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Patent Agency Ranking
公开(公告)号：US20210321881A1
公开(公告)日：2021-10-21
申请号：US17193548
申请日：2021-03-05
Applicant: HeartWare, Inc.
Inventor： Michael C. Brown , Veronica Ramos , Neil Voskoboynikov
IPC: A61B5/0215 , A61M60/126 , A61B5/00 , A61M5/142
Abstract: A method of determining a presence of suction in a patient having an implantable blood pump from down-sampled log files. The method comprising calculating a waveform index for each of a plurality of flow rate data points from the down-sampled log files. The calculated waveform index is compared with a predetermined waveform index threshold. A non-suction trough baseline is calculated from the plurality of flow rate data points. A difference between a measured trough and a calculated non-suction trough baseline is compared with a predetermined threshold. The presence of suction for each of the plurality of flow rate data points is determined if the calculated waveform index is greater than the predetermined waveform index threshold and the difference between the measured trough and a calculated non-suction trough baseline is greater than the predetermined threshold.
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公开(公告)号：US10688232B2
公开(公告)日：2020-06-23
申请号：US16202903
申请日：2018-11-28
Applicant: HeartWare, Inc.
Inventor： Neil Voskoboynikov , Pedro Grave de Peralta
Abstract: A method of estimating an amount of work available to be performed by a blood pump implanted in a patient includes calculating a first coordinate value characterizing a volume of blood impelled in the pump and a second coordinate value characterizing a differential pressure across the pump for each of a plurality of flow rate data points of a given cardiac cycle of the patient, each flow rate data point indicative of a flow rate of blood through the pump. An area enclosed by the first and second coordinate values of the plurality of flow rate data points is determined, the determined area being indicative of an amount of work available to be performed by the blood pump.
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公开(公告)号：US09579432B2
公开(公告)日：2017-02-28
申请号：US14019219
申请日：2013-09-05
Applicant: HeartWare, Inc.
Inventor： Dan Tamez , Neil Voskoboynikov
CPC classification number: A61M1/1086 , A61M1/10 , A61M1/1008 , A61M1/101 , A61M1/1031 , A61M1/1036 , A61M1/122 , A61M2205/0211 , A61M2205/3334 , A61M2205/3375
Abstract: A blood pump with an integrated flow sensor is provided. The blood pump may include an implantable pump for pumping blood having a housing, a flow path extending within the housing and at least one movable element within the housing for impelling blood along the flow path and a sensor for measuring the flow rate of blood through the pump. According to one embodiment, the sensor may be mounted to the housing of the pump. In accordance with a further embodiment, the housing may have an exterior surface defining a cavity, and the sensor may be located within the cavity.
Abstract translation: 提供具有集成流量传感器的血泵。 血液泵可以包括用于泵送血液的可植入泵，其具有壳体，在壳体内延伸的流路和壳体内的至少一个可移动元件，用于沿着流动路径推动血液;以及传感器，用于测量血液通过 泵。 根据一个实施例，传感器可以安装到泵的壳体。 根据另一实施例，壳体可以具有限定空腔的外表面，并且传感器可以位于空腔内。
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公开(公告)号：US10786611B2
公开(公告)日：2020-09-29
申请号：US15834487
申请日：2017-12-07
Applicant: HeartWare, Inc.
Inventor： Dan Tamez , Neil Voskoboynikov
Abstract: A blood pump with an integrated flow sensor is provided. The blood pump may include an implantable pump for pumping blood having a housing, a flow path extending within the housing and at least one movable element within the housing for impelling blood along the flow path and a sensor for measuring the flow rate of blood through the pump. According to one embodiment, the sensor may be mounted to the housing of the pump. In accordance with a further embodiment, the housing may have an exterior surface defining a cavity, and the sensor may be located within the cavity.
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公开(公告)号：US10561774B2
公开(公告)日：2020-02-18
申请号：US15648735
申请日：2017-07-13
Applicant: HeartWare, Inc.
Inventor： Neil Voskoboynikov , Pedro E. Grave De Peralta , Veronica Ramos
Abstract: A method of detecting a disruption in a diurnal rhythm of a patient having an implantable blood pump comprising calculating a moving average convergence divergence (MACD) based on power consumed by the implantable blood pump to maintain a constant rotational speed of an impeller of the implantable blood pump and generating an alert when the calculated MACD does not cross a MACD zero line for a predetermined MACD zero line crossing time threshold.
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