公开(公告)号：US20240253040A1

公开(公告)日：2024-08-01

申请号：US18427503

申请日：2024-01-30

Applicant: IDEXX Laboratories, Inc.

Inventor： Murthy Yerramilli ,  Jennifer Gagner ,  William Foster ,  Eugene Chan ,  Pradeep Sathyanarayana

IPC: B01L3/00

CPC classification number: B01L3/502761 ,  B01L2400/0427 ,  B01L2400/043

Abstract: A method for preparing for manipulating a droplet on a surface of a cartridge, wherein the droplet comprises at least one paramagnetic, bar-coded bead is disclosed. The method includes transporting, via a plurality of electrodes of the cartridge, the droplet on the surface of the cartridge, wherein the plurality of electrodes is configured to transport the droplet on the surface of the cartridge. The method also includes immobilizing, via at least one magnet of the cartridge, the droplet on the surface of the cartridge, wherein the at least one magnet is configured to immobilize the droplet on the surface of the cartridge.

公开(公告)号：US20240216908A1

公开(公告)日：2024-07-04

申请号：US18390889

申请日：2023-12-20

Applicant: IDEXX Laboratories, Inc.

Inventor： Murthy Yerramilli ,  Eugene Chan ,  William Foster ,  Jennifer Gagner

IPC: B01L3/00 ,  G01N33/543

CPC classification number: B01L3/5023 ,  G01N33/54388 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2200/16 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/12

Abstract: A device for supporting lateral flow of a liquid. The device includes a support layer having a fluid impervious material with a porated region to allow for penetration of liquid through the support layer, and a membrane layer of bonded microparticle adhered to the support. The device may be used in an apparatus for the detection of analytes in samples.

公开(公告)号：US20180188250A1

公开(公告)日：2018-07-05

申请号：US15908313

申请日：2018-02-28

Applicant: IDEXX Laboratories, Inc.

Inventor： Eugene Chan ,  Keith Nassif

IPC: G01N33/573 ,  G01N35/00 ,  G01N33/543

CPC classification number: G01N33/573 ,  G01N33/54366 ,  G01N35/00029 ,  G01N2035/00138 ,  G01N2333/918

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections—a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

公开(公告)号：US20240269670A1

公开(公告)日：2024-08-15

申请号：US18434614

申请日：2024-02-06

Applicant: IDEXX LABORATORIES, INC.

Inventor： Murthy Yerramilli ,  Jennifer Gagner ,  William Foster ,  Eugene Chan ,  Wayne Bell ,  Asante Malima

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/50273 ,  B01L3/502746 ,  B01L3/502761 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2200/0689 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0864 ,  B01L2300/123 ,  B01L2300/18 ,  B01L2400/0409 ,  B01L2400/0442

Abstract: A method for preparing analyzing a droplet on a surface of a cartridge, wherein the droplet comprises a plurality of particles is disclosed. The method includes transporting, via a plurality of electrodes of the cartridge, the droplet along a single path on the surface of the cartridge, wherein the single path is substantially linear and the plurality of electrodes is configured to transport the droplet along the single path on the surface of the cartridge. The method also includes analyzing the droplet at one or more locations along the single path on the surface of the cartridge.

公开(公告)号：US11047857B2

公开(公告)日：2021-06-29

申请号：US15908313

申请日：2018-02-28

Applicant: IDEXX Laboratories, Inc.

Inventor： Eugene Chan ,  Keith Nassif

IPC: G01N33/573 ,  G01N33/543 ,  G01N35/00

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections—a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

公开(公告)号：US09933428B2

公开(公告)日：2018-04-03

申请号：US14358280

申请日：2013-01-07

Applicant: IDEXX Laboratories, Inc.

Inventor： Eugene Chan ,  Keith Nassif

IPC: G01N33/557 ,  G01N33/573 ,  G01N35/00 ,  G01N33/543

CPC classification number: G01N33/573 ,  G01N33/54366 ,  G01N35/00029 ,  G01N2035/00138 ,  G01N2333/918

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections—a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

公开(公告)号：US20140315216A1

公开(公告)日：2014-10-23

申请号：US14358280

申请日：2013-01-07

Applicant: IDEXX Laboratories, Inc.

Inventor： Eugene Chan ,  Keith Nassif

IPC: G01N33/573

CPC classification number: G01N33/573 ,  G01N33/54366 ,  G01N35/00029 ,  G01N2035/00138 ,  G01N2333/918

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections—a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

Abstract translation: 用于干化学分析仪器的免疫测定试验片包括由两个可配置部分形成的滑动壳体或壳体 - 滑动盖件和滑动底部件。 滑动壳体限定内部空腔，其中位于片状多孔载体矩阵中。 滑动盖件具有通过其厚度形成的开口，以暴露流体流动基体的中心部分，使得精确体积的血液，血清等的液体样品优选与共轭试剂预混合，并且精确体积 洗涤剂和底物（检测剂试剂）可以通过分析仪器的计量装置通过盖开口沉积在基质上。 免疫测定试验载玻片的底部是透明的，并且通过分析仪器的输送机构通过反射计或荧光计使载玻片移动，以进行反射或荧光测量。