公开(公告)号：US11122978B1

公开(公告)日：2021-09-21

申请号：US17010500

申请日：2020-09-02

Applicant: ILLUMISONICS INC.

Inventor： Parsin Haji Reza ,  Zohreh Hosseinaee ,  Kevan Bell ,  Saad Abbasi ,  Ben Eccelstone

IPC: A61B5/00 ,  G01B9/02 ,  G01N29/24 ,  G01N21/17

Abstract: A dual-modality photoacoustic remote sensing combined with optical coherence tomography (PARS-OCT) system for visualizing details in a sample, the system comprising one or more light sources configured to generate (1) one or more excitation beams configured to generate signals in the sample at one or more first locations below a surface of the sample; (2) one or more interrogation beams incident on the sample at one or more second locations; (3) a sample beam; and (4) a reference beam.

公开(公告)号：US11950882B2

公开(公告)日：2024-04-09

申请号：US18069791

申请日：2022-12-21

Applicant: ILLUMISONICS INC.

Inventor： Parsin Haji Reza ,  Kevan Bell

IPC: A61B5/00 ,  A61B1/00 ,  A61B1/06 ,  A61B5/02 ,  A61B5/145 ,  G01N21/17 ,  G01N21/64

CPC classification number: A61B5/0095 ,  A61B1/00004 ,  A61B1/00172 ,  A61B1/0615 ,  A61B5/0035 ,  A61B5/14532 ,  A61B5/14542 ,  G01N21/1702 ,  G01N21/64 ,  A61B1/00117 ,  A61B5/02042 ,  G01N2021/1706 ,  G01N2201/0683 ,  G01N2201/08

Abstract: A photoacoustic remote sensing system for imaging a subsurface structure in a sample, comprising exactly one laser source configured to generate a pulsed or intensity-modulated excitation beam configured to generate ultrasonic pressure signals in the sample at an excitation location, and an interrogation beam incident on the sample at the excitation location, a portion of the interrogation beam returning from the sample that is indicative of the generated ultrasonic pressure signals, an optical system configured to focus the excitation beam and the interrogation beam below a surface of the sample, a detector configured to detect the returning portion of the interrogation beam, and a processor configured to calculate an image of the sample based on a detected intensity modulation of the returning portion of the interrogation beam from below the surface of the sample.

公开(公告)号：US11841315B2

公开(公告)日：2023-12-12

申请号：US16629371

申请日：2019-12-19

Applicant: ILLUMISONICS INC.

Inventor： Parsin Haji Reza ,  Kevan Bell

IPC: G01N21/17 ,  A61B5/00

CPC classification number: G01N21/1702 ,  A61B5/0095 ,  G01N2021/1706 ,  G01N2201/06113

Abstract: A photoacoustic remote sensing system (PARS) for imaging a subsurface structure in a sample, comprising one or more laser sources configured to generate a plurality of excitation beams configured to generate pressure signals in the sample at an excitation location, and a plurality of interrogation beams incident on the sample at the excitation location, a portion of the plurality of interrogation beams returning from the sample that is indicative of the generated pressure signals, an optical system configured to focus the plurality of excitation beams at a first focal point and the plurality of interrogation beams at a second focal point, the first and second focal points being below the surface of the sample, and a plurality of detectors each configured to detect a returning portion of at least one of the plurality of interrogation beams.

公开(公告)号：US11786128B2

公开(公告)日：2023-10-17

申请号：US17394919

申请日：2021-08-05

Applicant: ILLUMISONICS INC.

Inventor： Parsin Haji Reza ,  Zohreh Hosseinaee ,  Kevan Bell ,  Saad Abbasi ,  Benjamin Ecclestone

IPC: A61B5/00 ,  G01B9/02091 ,  G01N29/24 ,  G01N21/17 ,  G01N21/64 ,  G01N29/44 ,  A61B5/01

CPC classification number: A61B5/0066 ,  A61B5/0035 ,  A61B5/0071 ,  G01B9/02091 ,  G01N21/1702 ,  G01N21/6456 ,  G01N21/6486 ,  G01N29/2418 ,  G01N29/4436 ,  A61B5/0095 ,  A61B5/01 ,  G01N2291/02475

Abstract: A method for visualizing details in a sample including directing an excitation beam to an excitation location below a surface of the sample, to generate signals in the sample; directing an interrogation beam toward the excitation location of the sample; directing a signal enhancement beam to the sample, to raise a temperature of a portion of the sample by 5 Kelvin or less, compared to a temperature of the portion of the sample in absence of the signal enhancement beam; detecting a portion of the interrogation beam returning from the sample that is indicative of the generated signals.

公开(公告)号：US11564578B2

公开(公告)日：2023-01-31

申请号：US16647076

申请日：2020-03-03

Applicant: ILLUMISONICS INC.

Inventor： Parsin Haji Reza ,  Kevan Bell

IPC: G01B11/02 ,  A61B5/00 ,  G01N21/17 ,  A61B1/00 ,  A61B5/145 ,  A61B1/06 ,  G01N21/64 ,  A61B5/02

Abstract: A photoacoustic remote sensing system for imaging a subsurface structure in a sample, comprising exactly one laser source configured to generate a pulsed or intensity-modulated excitation beam configured to generate ultrasonic pressure signals in the sample at an excitation location, and an interrogation beam incident on the sample at the excitation location, a portion of the interrogation beam returning from the sample that is indicative of the generated ultrasonic pressure signals, an optical system configured to focus the excitation beam and the interrogation beam below a surface of the sample, a detector configured to detect the returning portion of the interrogation beam, and a processor configured to calculate an image of the sample based on a detected intensity modulation of the returning portion of the interrogation beam from below the surface of the sample.