中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

19 records (took 0.019 seconds)

    PULSE-BURST ASSISTED ELECTROSPRAY IONIZATION MASS SPECTROMETER
    2.
    发明申请
    PULSE-BURST ASSISTED ELECTROSPRAY IONIZATION MASS SPECTROMETER 审中-公开
    脉冲激光辅助电喷雾离子质谱仪

    公开(公告)号：US20150187558A1

    公开(公告)日：2015-07-02

    申请号：US14142240

    申请日：2013-12-27

    Applicant: IMRA AMERICA, INC.

    Inventor： Andrew A. MILLS ,  Martin E. FERMANN ,  Jiahui PENG ,  Robert J. LEVIS

    IPC: H01J49/16 ,  G01N30/96 ,  G01N33/483 ,  G01N33/50 ,  G01N33/68 ,  G01N33/92 ,  G01N33/94 ,  G01N33/02 ,  H01J49/04 ,  G01N33/49

    CPC classification number: G01N33/02 ,  G01N30/7266 ,  G01N33/4833 ,  G01N33/49 ,  H01J49/0463

    Abstract: The present invention relates to a mass spectrometer system, which combines laser desorption with pulse bursts comprising a train of ultrashort pulses and electrospray ionization. The pulse separation between individual pulses within the pulse burst is selected such that transient phenomena on an irradiated sample do not fully relax between individual pulses. Pulses with pulse widths ranging from fs to sub ns are conveniently implemented. The pulse widths can be selected to allow for multi-photon excitation of a sample while at the same time minimizing heat accumulation in a sample. Low cost laser systems such as fiber lasers can be configured to generate appropriate pulse bursts. The technique is suitable for mass spectrometry imaging with high spatial resolution. The laser system can serve as an electronic clock to which the whole mass spectrometry system or mass spectrometry imaging system is synchronized.

    Abstract translation: 本发明涉及一种将激光解吸与脉冲串组合在一起的质谱仪系统，脉冲串包括一串超短脉冲串和电喷雾电离。 选择脉冲脉冲串内的各个脉冲之间的脉冲间隔，使得被照射样品上的瞬态现象在各个脉冲之间不完全松弛。 脉冲宽度范围从fs到sub ns的脉冲是方便的。 可以选择脉冲宽度以允许样品的多光子激发，同时最小化样品中的热积聚。 诸如光纤激光器的低成本激光系统可被配置成产生适当的脉冲串。 该技术适用于具有高空间分辨率的质谱成像。 激光系统可以用作整个质谱系统或质谱成像系统同步的电子时钟。

    COMPACT, COHERENT, HIGH BRIGHTNESS LIGHT SOURCES FOR THE MID AND FAR IR
    5.
    发明申请
    COMPACT, COHERENT, HIGH BRIGHTNESS LIGHT SOURCES FOR THE MID AND FAR IR 审中-公开
    紧凑，相关，中等和远红外的高亮度光源

    公开(公告)号：US20160099537A1

    公开(公告)日：2016-04-07

    申请号：US14965114

    申请日：2015-12-10

    Applicant: IMRA AMERICA, INC.

    Inventor： Martin E. FERMANN

    IPC: H01S3/067 ,  H01S3/16 ,  B23K26/362 ,  H01S3/11

    CPC classification number: H01S3/06725 ,  B23K26/352 ,  B23K26/361 ,  B23K26/362 ,  H01S3/06712 ,  H01S3/06741 ,  H01S3/0675 ,  H01S3/06754 ,  H01S3/06791 ,  H01S3/10015 ,  H01S3/10092 ,  H01S3/1112 ,  H01S3/1118 ,  H01S3/1608 ,  H01S3/1616

    Abstract: Compact high brightness light sources for the mid and far IR spectral region, and exemplary applications are disclosed based on passively mode locked Tm fiber comb lasers. In at least one embodiment the coherence of the comb sources is increased in a system utilizing an amplified single-frequency laser to pump the Tm fiber comb laser. The optical bandwidth generated by the passively mode locked Tm fiber comb laser is further decreased by using simultaneous 2nd and 3rd order dispersion compensation using either appropriate chirped fiber Bragg gratings for dispersion compensation, or fibers with appropriately selected values of 2nd and 3rd order dispersion. Fibers with large anomalous values of third order dispersion, or fibers with large numerical apertures, for example fibers having air-holes formed in the fiber cladding may be utilized.

    Abstract translation: 基于被动模式锁定的Tm光纤梳状激光器公开了用于中红外光谱区域和远红外光谱区域的紧凑型高亮度光源，以及示例性应用。 在至少一个实施例中，在使用放大的单频激光器来泵浦Tm纤维梳状激光器的系统中，梳状源的相干性增加。 通过使用用于色散补偿的适当的啁啾光纤布拉格光栅或具有适当选择的二阶和三阶色散值的光纤，通过使用同时的二次和三阶色散补偿来进一步减少由被动模式锁定的Tm光纤梳状激光器产生的光学带宽。 可以使用具有三阶分散的大异常值的纤维或具有大数值孔径的纤维，例如在纤维包层中形成具有空气孔的纤维。

    COMPACT ULTRA-SHORT PULSE SOURCE AMPLIFIERS
    6.
    发明申请
    COMPACT ULTRA-SHORT PULSE SOURCE AMPLIFIERS 审中-公开
    紧凑型超短脉冲源放大器

    公开(公告)号：US20150311666A1

    公开(公告)日：2015-10-29

    申请号：US14571367

    申请日：2013-10-16

    Applicant: IMRA AMERICA, INC.

    Inventor： Martin E. FERMANN

    IPC: H01S3/11 ,  H01J49/16 ,  H01S3/067

    CPC classification number: H01S3/1106 ,  B23K26/0624 ,  H01J49/161 ,  H01S3/0057 ,  H01S3/06708 ,  H01S3/06741 ,  H01S3/0675 ,  H01S3/06754 ,  H01S3/094003 ,  H01S3/094026 ,  H01S3/094042 ,  H01S3/094061 ,  H01S3/0941 ,  H01S3/109 ,  H01S3/1115

    Abstract: The present invention relates to compact, low noise, ultra-short pulse sources based on fiber amplifiers, and various applications thereof. At least one implementation includes an optical amplification system having a fiber laser seed source producing seed pulses at a repetition rate corresponding to the fiber laser cavity round trip time. A nonlinear pulse transformer, comprising a fiber length greater than about 10 m, receives a seed pulse at its input and produces a spectrally broadened output pulse at its output, the output pulse having a spectral bandwidth which is more than 1.5 times a spectral bandwidth of a seed pulse. A fiber power amplifier receives and amplifies spectrally broadened output pulses. A pulse compressor is configured to temporally compress spectrally broadened pulses amplified by said power amplifier. Applications include micro-machining, ophthalmology, molecular desorption or ionization, mass-spectroscopy, and/or laser-based, biological tissue processing.

    Abstract translation: 本发明涉及基于光纤放大器的紧凑，低噪声，超短脉冲源及其各种应用。 至少一个实施方案包括具有光纤激光种子源的光放大系统，其以对应于光纤激光腔往返时间的重复频率产生种子脉冲。 包括光纤长度大于约10微米的非线性脉冲变压器在其输入处接收种子脉冲，并在其输出端产生光谱扩展的输出脉冲，其输出脉冲的光谱带宽大于光谱带宽的1.5倍 种子脉冲。 光纤功率放大器接收并放大光谱扩展的输出脉冲。 脉冲压缩器被配置为在时间上压缩由所述功率放大器放大的频谱变宽的脉冲。 应用包括微加工，眼科学，分子解吸或离子化，质谱法和/或基于激光的生物组织处理。

    COMPACT COHERENT HIGH BRIGHTNESS LIGHT SOURCE FOR THE MID-IR AND FAR IR
    7.
    发明申请
    COMPACT COHERENT HIGH BRIGHTNESS LIGHT SOURCE FOR THE MID-IR AND FAR IR 审中-公开
    紧凑的高亮度光源，用于中红外和红外线

    公开(公告)号：US20150023628A1

    公开(公告)日：2015-01-22

    申请号：US14508056

    申请日：2014-10-07

    Applicant: IMRA AMERICA, INC.

    Inventor： Martin E. FERMANN ,  Ingmar HARTL

    IPC: H01S3/00

    CPC classification number: H01S3/0092 ,  G02B6/02038 ,  G02F1/3534 ,  G02F1/365 ,  G02F2001/3528 ,  H01S3/067 ,  H01S3/06725 ,  H01S3/094046 ,  H01S3/109 ,  H01S3/1106 ,  H01S3/30 ,  H01S3/302

    Abstract: Compact laser systems are disclosed which include ultrafast laser sources in combination with nonlinear crystals or waveguides. In some implementations fiber based mid-IR sources producing very short pulses and/or mid-IR sources based on a mode locked fiber lasers are utilized. A difference frequency generator receives outputs from the ultrafast sources, and generates an output including a difference frequency. The output power from the difference frequency generator can further be enhanced via the implementation of large core dispersion shifted fibers. Exemplary applications of the compact, high brightness mid-IR light sources include medical applications, spectroscopy, ranging, sensing and metrology.

    Abstract translation: 公开了紧凑的激光系统，其包括与非线性晶体或波导组合的超快激光源。 在一些实现中，利用基于模式锁定光纤激光器产生非常短脉冲和/或中红外光源的基于光纤的中红外光源。 差频发生器接收来自超快源的输出，并产生包括差频的输出。 来自差分频率发生器的输出功率可以通过实施大型核心色散位移光纤进一步提高。 紧凑的高亮度中红外光源的示例性应用包括医疗应用，光谱学，测距，感测和计量学。

    COMPACT OPTICAL FREQUENCY COMB SYSTEMS
    8.
    发明申请
    COMPACT OPTICAL FREQUENCY COMB SYSTEMS 审中-公开
    紧凑的光学频率系统

    公开(公告)号：US20140321483A1

    公开(公告)日：2014-10-30

    申请号：US14325721

    申请日：2014-07-08

    Applicant: IMRA AMERICA, INC.

    Inventor： Martin E. FERMANN ,  Thomas R. SCHIBLI ,  Ingmar HARTL

    IPC: H01S3/11

    CPC classification number: H01S3/1115 ,  H01S3/0092 ,  H01S3/06712 ,  H01S3/06725 ,  H01S3/08059 ,  H01S3/10046 ,  H01S3/105 ,  H01S3/1053 ,  H01S3/1118 ,  H01S3/1616 ,  H01S3/176

    Abstract: Compact optical frequency sources are described. The comb source may include an intra-cavity optical element having a multi-material integrated structure with an electrically controllable active region. The active region may comprise a thin film. By way of example, the thin film and an insulating dielectric material disposed between two electrodes can provide for rapid loss modulation. In some embodiments the thin film may comprise graphene. In various embodiments of a frequency comb laser, rapid modulation of the CEO frequency can be implemented via electric modulation of the transmission or reflection loss of an additional optical element, which can be the saturable absorber itself. In another embodiment, the thin film can also be used as a saturable absorber in order to facilitate passive modelocking. In some implementations the optical element may be formed on a cleaved or polished end of an optical fiber.

    Abstract translation: 描述了紧凑的光频源。 梳状光源可以包括具有电子可控有源区域的多材料集成结构的腔内光学元件。 有源区可以包括薄膜。 作为示例，设置在两个电极之间的薄膜和绝缘介电材料可以提供快速损耗调制。 在一些实施例中，薄膜可以包括石墨烯。 在频率梳状激光器的各种实施例中，CEO频率的快速调制可以通过附加光学元件的传输或反射损耗的电调制来实现，其可以是可饱和吸收体本身。 在另一个实施例中，薄膜也可以用作饱和吸收体，以便于被动锁模。 在一些实施方式中，光学元件可以形成在光纤的切割或抛光端上。

    COMPACT COHERENT HIGH BRIGHTNESS LIGHT SOURCE FOR THE MID-IR AND FAR IR
    9.
    发明申请
    COMPACT COHERENT HIGH BRIGHTNESS LIGHT SOURCE FOR THE MID-IR AND FAR IR 有权
    紧凑的高亮度光源，用于中红外和红外线

    公开(公告)号：US20140219296A1

    公开(公告)日：2014-08-07

    申请号：US13682309

    申请日：2012-11-20

    Applicant: IMRA AMERICA, INC.

    Inventor： Martin E. FERMANN ,  Jens BETHGE ,  Ingmar HARTL

    IPC: H01S3/00 ,  G02B6/02

    CPC classification number: H01S3/0092 ,  G02B6/02038 ,  G02F1/3534 ,  G02F1/365 ,  G02F2001/3528 ,  H01S3/067 ,  H01S3/06725 ,  H01S3/094046 ,  H01S3/109 ,  H01S3/1106 ,  H01S3/30 ,  H01S3/302

    Abstract: Compact laser systems are disclosed which include ultrafast laser sources in combination with nonlinear crystals or waveguides. In some implementations fiber based mid-IR sources producing very short pulses and/or mid-IR sources based on a mode locked fiber lasers are utilized. A difference frequency generator receives outputs from the ultrafast sources, and generates an output including a difference frequency. The output power from the difference frequency generator can further be enhanced via the implementation of large core dispersion shifted fibers. Exemplary applications of the compact, high brightness mid-IR light sources include medical applications, spectroscopy, ranging, sensing and metrology.

    Abstract translation: 公开了紧凑的激光系统，其包括与非线性晶体或波导组合的超快激光源。 在一些实现中，利用基于模式锁定光纤激光器产生非常短脉冲和/或中红外光源的基于光纤的中红外光源。 差频发生器接收来自超快源的输出，并产生包括差频的输出。 来自差分频率发生器的输出功率可以通过实施大型核心色散位移光纤进一步提高。 紧凑的高亮度中红外光源的示例性应用包括医疗应用，光谱学，测距，感测和计量学。

    COMPACT, COHERENT, HIGH BRIGHTNESS LIGHT SOURCES FOR THE MID AND FAR IR
    10.
    发明申请
    COMPACT, COHERENT, HIGH BRIGHTNESS LIGHT SOURCES FOR THE MID AND FAR IR 审中-公开
    紧凑，相关，中等和远红外的高亮度光源

    公开(公告)号：US20140202994A1

    公开(公告)日：2014-07-24

    申请号：US14221704

    申请日：2014-03-21

    Applicant: IMRA AMERICA, INC.

    Inventor： Martin E. FERMANN

    IPC: H01S3/067 ,  B23K26/00

    CPC classification number: H01S3/06725 ,  B23K26/352 ,  B23K26/361 ,  B23K26/362 ,  H01S3/06712 ,  H01S3/06741 ,  H01S3/0675 ,  H01S3/06754 ,  H01S3/06791 ,  H01S3/10015 ,  H01S3/10092 ,  H01S3/1112 ,  H01S3/1118 ,  H01S3/1608 ,  H01S3/1616

    Abstract: Compact high brightness light sources for the mid and far IR spectral region, and exemplary applications are disclosed based on passively mode locked Tm fiber comb lasers. In at least one embodiment the coherence of the comb sources is increased in a system utilizing an amplified single-frequency laser to pump the Tm fiber comb laser. The optical bandwidth generated by the passively mode locked Tm fiber comb laser is further decreased by using simultaneous 2nd and 3rd order dispersion compensation using either appropriate chirped fiber Bragg gratings for dispersion compensation, or fibers with appropriately selected values of 2nd and 3rd order dispersion. Fibers with large anomalous values of third order dispersion, or fibers with large numerical apertures, for example fibers having air-holes formed in the fiber cladding may be utilized.

    Abstract translation: 基于被动模式锁定的Tm光纤梳状激光器公开了用于中红外光谱区域和远红外光谱区域的紧凑型高亮度光源，以及示例性应用。 在至少一个实施例中，在使用放大的单频激光器来泵浦Tm纤维梳状激光器的系统中，梳状源的相干性增加。 通过使用用于色散补偿的适当的啁啾光纤布拉格光栅或具有适当选择的二阶和三阶色散值的光纤，通过使用同时的二次和三阶色散补偿来进一步减少由被动模式锁定的Tm光纤梳状激光器产生的光学带宽。 可以使用具有三阶分散的大异常值的纤维或具有大数值孔径的纤维，例如在纤维包层中形成具有空气孔的纤维。

Patent Agency Ranking