公开(公告)号：US11002681B2

公开(公告)日：2021-05-11

申请号：US15781150

申请日：2016-01-27

Applicant: INDIAN INSTITUTE OF SCIENCE

Inventor： Siva Umapathy ,  Deepak Kumar Saini ,  Srividya Kumar

IPC: G01N21/65 ,  G01N21/94 ,  C12Q1/04 ,  G01N1/34 ,  G01N33/18

Abstract: The invention provides a method for rapid detection of a specific bacterial species. The method includes preparing a sample, irradiating the prepared sample with an electromagnetic radiation of specific wavelength, capturing the electromagnetic radiation scattered by the sample to obtain a Raman spectra and analyzing the Raman spectra to obtain a unique biochemical signature. The unique biochemical signature identifies a single bacterium within the sample. The method also provides for rapid detection of a group of bacterial species within the sample. The method takes about 1 minute to about 1 hour for the detection of specific bacterial species.

公开(公告)号：US12281987B2

公开(公告)日：2025-04-22

申请号：US18269557

申请日：2021-12-22

Applicant: INDIAN INSTITUTE OF SCIENCE

Inventor： Siva Umapathy ,  Sanchita Sil ,  Dipak Kumbhar ,  Srividya Kumar

IPC: G01N21/65

Abstract: The invention provides a method for homogenized coherent excitation of a sample for determining molecular structure. The method includes selecting a monochromatic coherent light, homogenizing the monochromatic coherent light; irradiating the sample with the homogenized monochromatic light; collecting the Raman scattered light to obtain a profile and analyzing the profile to obtain chemical specific signature of the sample. The invention also provides a method for obtaining two dimensional imaging of a sample using irradiation of large sample area by homogenized monochromatic light without compromise in spatial resolution. A system for homogenized coherent excitation of a sample for determining molecular structure is also provided.