公开(公告)号：US20140342363A1

公开(公告)日：2014-11-20

申请号：US13898064

申请日：2013-05-20

Applicant: Intelligent Bio-Systems, Inc.

Inventor： Steven Gordon ,  Phillip A. Veatch

IPC: C12Q1/68

Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.

Abstract translation: 本发明提供了方法和组合物，包括但不限于使用例如通过合成方法的测序获得的数据来确定核苷酸序列中核酸的身份的算法，计算机可读介质，计算机程序，装置和系统。 本发明的方法包括校正核苷酸测序期间遇到的一种或多种现象，例如通过合成方法进行测序。 这些现象包括但不限于序列引导，序列滞后，光谱串扰以及由照明和/或滤波器响应变化引起的噪声。

公开(公告)号：US20150099647A1

公开(公告)日：2015-04-09

申请号：US14456321

申请日：2014-08-11

Applicant: Intelligent Bio-Systems, Inc.

Inventor： Steven Gordon ,  Phillip A. Veatch

IPC: C12Q1/68

CPC classification number: C12Q1/6869 ,  C12Q1/6806 ,  C12Q1/6825 ,  G06F19/20 ,  C12Q2527/137 ,  C12Q2525/186 ,  C12Q2525/117 ,  C12Q2565/601 ,  C12Q2563/107 ,  C12Q2537/165

Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.

Abstract translation: 本发明提供了方法和组合物，包括但不限于使用例如通过合成方法的测序获得的数据来确定核苷酸序列中核酸的身份的算法，计算机可读介质，计算机程序，装置和系统。 本发明的方法包括校正核苷酸测序期间遇到的一种或多种现象，例如通过合成方法进行测序。 这些现象包括但不限于序列引导，序列滞后，光谱串扰以及由照明和/或滤波器响应变化引起的噪声。