Abstract:
A method and apparatus for providing status of a parameter that includes detecting an alert level of a parameter monitored by an implanted medical device, transmitting data corresponding to the detected alert level from the implanted medical device to an external monitor, scheduling a follow-up interrogation session after receiving transmitted data corresponding to the detected alert level, and retrieving updated data from the implanted medical device corresponding to the monitored parameter during the follow-up interrogation session.
Abstract:
A multilayer valve subassembly (50) comprises an interface layer (60) having an interface layer flap (62, 64); a cover layer (70) having a cover layer flap (72, 74); and, an intermediate layer (80) positioned between the interface layer and the cover layer. The intermediate layer (80) has an intermediate layer flap (82, 84) essentially aligned with the interface layer flap and the cover layer flap. A first bond (102) adheres the cover layer (70) to the interface layer (60); a flap bond (92, 94) seals the interface layer flap (82, 84) between the cover layer flap (72, 74) and the interface layer flap (62, 64) and thereby forms a multilayer valve flap (52, 54) which is insulated from fluid which travels through the valve. In an example embodiment, the each of the interface layer flap, the cover layer flap, and the interface layer flap has a substantially U-shape. Preferably the interface layer is not in contact with the first bond or the second bond and has a size that permits the interface layer to float in a sandwich pocket formed between the interface layer and the cover layer.
Abstract:
A mechanism for adjusting the tilt angle of slats of a slat blind positioned between the panes of glass of a sealed window unit is described. The mechanism is sealed about an aperture through one of the panes and includes a flexible cable within a flexible tube extending from the mechanism to the control mechanism for the blind. The flexible tube maintains the window seal and the cable enables torque to be transmitted from the mechanism to the tilt control mechanism of the blind, thereby allowing direct external mechanical control of the tilt angle of the slats without breaking the hermetic seal for the window.
Abstract:
The disclosure relates to novel particle compositions and methods of making said compositions having applications in nucleic acid analysis, as well as apparatuses and systems for the same.
Abstract:
A medical information communication system and corresponding methods are described. The system can permit monitoring the performance of an implantable medical device (IMD) implanted within a body of a patient, monitoring the health of the patient, and/or remotely delivering a therapy to the patient through the IMD. The IMD can be capable of bidirectional communication with a clinician. Further, the system can comprise a communication availability indicator to indicate whether the IMD is available for communication.
Abstract:
The present invention provides human protein arrays that include at least 1000 human proteins. In another embodiment, the present invention provides a method for identifying a substrate of an enzyme, comprising contacting the enzyme with a positionally addressable array comprising at least 100 proteins immobilized on functionalized glass surface, and identifying a protein on the positionally addressable array that is bound and/or modified by the enzyme, wherein a binding or modifying of the protein by the enzyme indicates that the protein is a substrate for the enzyme. In additional embodiments, provided herein are methods for making an array of at least 1000 human proteins under non-denaturing conditions, including human proteins that are difficult to express and/or difficult to isolate in a non-denatured state.
Abstract:
A method of forming or treating an article or preform (10) and an article or preform made according to the method are provided. The method includes the step of providing around at least part of the article or preform (10) a generally tubular element (14) whose effective cross-section tends to reduce on extension, and applying an extension load to the tubular element (14) thereby to apply a compression load to the exterior of the article or preform to aid consolidation thereof.
Abstract:
An alert system for alerting a clinician to an occurrence of an event detected by an implantable medical device includes a monitor and a patient management network. The implantable medical device includes a means for detecting the occurrence of the event and initiating a wireless transmission of data related to the event. The monitor is configured to receive the wireless transmission of data and transfer the data. The patient management network is configured to receive the data and store the data on a data storage device. The patient management network includes a web presentation service for creating a website from the data stored on the data storage device, the website configured to alert the clinician to the occurrence of the event.
Abstract:
The present invention provides human protein arrays that include at least 1000 human proteins. In another embodiment, the present invention provides a method for identifying a substrate of an enzyme, comprising contacting the enzyme with a positionally addressable array comprising at least 100 proteins immobilized on functionalized glass surface, and identifying a protein on the positionally addressable array that is bound and/or modified by the enzyme, wherein a binding or modifying of the protein by the enzyme indicates that the protein is a substrate for the enzyme. In additional embodiments, provided herein are methods for making an array of at least 1000 human proteins under non-denaturing conditions, including human proteins that are difficult to express and/or difficult to isolate in a non-denatured state.
Abstract:
Thermal exchange systems integrate a thermal transfer unit (22); a fluid cooling assembly (24); a pump (26); and a fan (28). The thermal transfer unit (22) interfaces with a body to be thermally conditioned and transfers thermal energy to a fluid. The fluid cooling assembly (24) cools the fluid obtained from the thermal transfer unit. The fan (28) directs air around the fluid cooling assembly (24). The pump (26) circulates fluid in a circuit comprising the pump (26), the fluid cooling assembly (2), and the thermal transfer unit (22). In one aspect of integrated system technology, the fan (28) and the circuit are compactly arranged and substantially situated entirely within a footprint (33) of a module housing (30). As another technological aspect, the fluid cooling assembly (24) comprises plural thermal dissipation plates (45) which are laminated together. In an example, non-limiting mode, the plural thermal dissipation plates (45) have features formed thereon by etching or stamping. Such features which may be etched or stamped can include one or more of an aperture (53/64) for defining a fluid inlet channel; a fluid return aperture (55); a thermal dissipation fin (67); a fluid return region (65) which is substantially surrounded by a lamination contact surface through which the thermal dissipation plate (45) is in contact with an adjacent thermal dissipation plate.