GENOMIC SERVICES PLATFORM SUPPORTING MULTIPLE APPLICATION PROVIDERS

    公开(公告)号:US20190026428A1

    公开(公告)日:2019-01-24

    申请号:US15872655

    申请日:2018-01-16

    Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants in response to the query.

    Input systems and methods for the evaluation and optimization of same
    2.
    发明授权
    Input systems and methods for the evaluation and optimization of same 失效
    输入系统和方法进行评估和优化

    公开(公告)号:US07259751B2

    公开(公告)日:2007-08-21

    申请号:US10771849

    申请日:2004-02-03

    CPC classification number: G06F3/0488 G06F3/0233

    Abstract: A method for evaluating an input system interfacing a human user with an electronic device uses empirically determined bi-action times for users to perform a second input action (e.g., pressing a second key) immediately after performing a first input action (e.g., pressing a first key). The bi-action times (or, more generally, n-action times) are used together with a selected interface map which associates input actions (e.g., pressing keys) to corresponding signifiers (e.g., characters) to calculate a peak expert input rate for the input system. One or more optimized interface maps can be found by combining the evaluation method with any of various optimization strategies. For example, one method for optimizing the input system repeatedly changes the interface map and recalculates the peak expert input rate, while another optimization method calculates peak expert input rates for multiple interface maps in parallel. The evaluation and optimization methods apply to a wide variety of users, input devices, and types of communication and control between them.

    Abstract translation: 用于评估与人电子设备接口的输入系统的方法使用经验确定的双动作时间,用户在执行第一输入动作之后立即执行第二输入动作(例如,按压第二键)(例如,按压 第一键)。 双动作时间(或更一般地,n动作时间)与选择的界面图一起使用,其将输入动作(例如,按键)与相应的符号(例如,字符)相关联,以计算峰值专家输入速率 输入系统。 通过将评估方法与各种优化策略中的任一种组合,可以找到一个或多个优化的界面图。 例如,一种用于优化输入系统的方法反复更改界面图并重新计算峰值专家输入速率,而另一种优化方法并行计算多个接口图的峰值专家输入速率。 评估和优化方法适用于各种用户,输入设备以及它们之间的通信和控制类型。

    GENOMIC SERVICES PLATFORM SUPPORTING MULTIPLE APPLICATION PROVIDERS

    公开(公告)号:US20190026429A1

    公开(公告)日:2019-01-24

    申请号:US15872784

    申请日:2018-01-16

    Abstract: Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample obtained from a user are received. The platform also includes a bioinformatics processing pipeline that includes a read alignment module configured to receive a genomics file from genomic sequencing equipment and use data contained therein to generate observed sequence data by aligning the sequence reads relative to a reference sequence. A variant calling module identifies observed variants in the observed sequence data and stores the observed variants in a variant calling file. A variant refinement module produces genotype data including a set of refined variants associated with the user, and a variant imputation module produces a set of imputed variants associated with the user. The variant imputation module can separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.

    Coin redemption machine control system and method
    6.
    发明申请
    Coin redemption machine control system and method 审中-公开
    硬币兑换机控制系统及方法

    公开(公告)号:US20070017776A1

    公开(公告)日:2007-01-25

    申请号:US11187776

    申请日:2005-07-21

    Applicant: James Warren

    Inventor: James Warren

    CPC classification number: G07F9/08 G07D11/00

    Abstract: A control system and method for operating a coin redemption machine includes a coin redemption machine functioning as a peripheral device to a separate computer linked to the coin redemption machine through a communications link for reciprocal communication between the coin redemption machine and the computer. The computer controls the activating and deactivating of the coin redemption machine; and the computer and coin redemption machine communicate through commands from the computer, followed by responses from the coin redemption machine.

    Abstract translation: 用于操作硬币兑换机的控制系统和方法包括用作通过连接到硬币兑换机的单独计算机的外围设备的硬币兑换机,该通信链路用于硬币兑换机和计算机之间的相互通信。 电脑控制硬币兑换机的启动和停用; 计算机和硬币兑换机通过计算机的命令进行通信,其次是硬币兑换机的响应。

    Permanent three-pole independent pole operation recloser simulator feature in a single-pole trip capable recloser control
    7.
    发明申请
    Permanent three-pole independent pole operation recloser simulator feature in a single-pole trip capable recloser control 有权
    永磁三极独立极操作重合器模拟器特点在单刀跳闸可重新控制

    公开(公告)号:US20060109600A1

    公开(公告)日:2006-05-25

    申请号:US10997602

    申请日:2004-11-23

    Applicant: James Warren

    Inventor: James Warren

    CPC classification number: H02H3/07

    Abstract: Disclosed is a permanent recloser simulator feature for use in a single-pole trip capable recloser control. The permanent recloser simulator feature includes a first logic circuit capable of enabling and disabling operation of the permanent recloser simulator feature in response to receipt of a binary logic signal, and a second logic circuit coupled to the first logic circuit where the second logic circuit is configured to provide an indication of a status of a first pole to a logic engine of the single-pole trip capable recloser control. The permanent recloser simulator feature may further include a third logic circuit associated with a second pole, and a fourth logic circuit associated with a third pole where both are coupled to the first logic circuit. Disabling means of the first logic circuit allow the first, second, third and fourth logic circuit to permanently reside in logic of the recloser control.

    Abstract translation: 公开了一种永久重合器模拟器功能,用于单刀跳闸可重新控制的控制。 永久重合器模拟器特征包括能够响应于接收到二进制逻辑信号而启用和禁用永久重合器模拟器特征的操作的第一逻辑电路,以及耦合到第一逻辑电路的第二逻辑电路,其中第二逻辑电路被配置 以提供第一极点的状态的指示到单刀跳闸能力重合器控制的逻辑引擎。 永久重合器模拟器特征还可以包括与第二极相关联的第三逻辑电路,以及与第三极相关联的第四逻辑电路,其中两个耦合到第一逻辑电路。 第一逻辑电路的禁用装置允许第一,第二,第三和第四逻辑电路永久地驻留在重合器控制的逻辑中。

    Centrally located ignition source in a combustion chamber
    8.
    发明申请
    Centrally located ignition source in a combustion chamber 失效
    位于燃烧室中心的点火源

    公开(公告)号:US20070095320A1

    公开(公告)日:2007-05-03

    申请号:US11589118

    申请日:2006-10-30

    Applicant: James Warren

    Inventor: James Warren

    CPC classification number: F02B75/282 F02P15/001

    Abstract: The centrally located ignition source in a combustion chamber is an electrical conductor spanning the general center of the combustion chamber, with a spark gap at the general center of the conductor. The device may be offset from the combustion chamber centerline, and/or the spark gap may be offset from the conductor center, as required. The centrally located ignition source is particularly well suited for use in an opposed piston engine having a rotary sleeve valve mechanism, with the conductor rotating with the sleeve valve and crossing the combustion chamber between the two pistons. An arcuate commutator section may be disposed upon the exterior of the rotary sleeve valve, with a contact finger making electrical contact between the electrical energy source and the commutator section to supply electrical energy to the ignition source. The device is also suitable for use in stationary installations, e.g., gas furnace combustors, etc.

    Abstract translation: 在燃烧室中的位于中心的点火源是跨过燃烧室的总体中心的电导体,在导体的中心处具有火花隙。 根据需要,该装置可以从燃烧室中心线偏移,和/或火花隙可能偏离导体中心。 位于中心的点火源特别适用于具有旋转套筒阀机构的相对活塞式发动机,导体与套筒阀一起旋转并与两个活塞之间的燃烧室相交。 弧形换向器部分可以设置在旋转套管阀的外部,其中接触指在电能源和换向器部分之间形成电接触,以向点火源提供电能。 该装置也适用于固定装置,例如燃气炉燃烧器等。

    High air flow foam bedding products
    9.
    发明申请
    High air flow foam bedding products 审中-公开
    高气流泡沫床上用品

    公开(公告)号:US20050278852A1

    公开(公告)日:2005-12-22

    申请号:US11150038

    申请日:2005-06-10

    Abstract: Foam bedding products including viscoelastic foam having a high airflow value that do not feel hot to the person sleeping on the products. One product is a pillow having a contoured core having sufficient firmness to provide effective support for a user and a hyper soft viscoelastic foam shell surrounding the core having sufficient firmness to maintain the appearance of a conventional pillow when supporting only a pillowcase or other bed coverings. The core may be made of higher density viscoelastic foam or of a resilient foam. Another product may be a mattress topper with or without foam cores for body support carried within slabs of high airflow viscoelastic foam.

    Abstract translation: 泡沫床上用品,包括具有高气流值的粘弹性泡沫,对于睡在产品上的人不感到热。 一种产品是一种枕头,其具有足够的坚硬度以为使用者提供有效的支撑,并且围绕该芯的超柔软的粘弹性泡沫壳具有足够的坚固度以在仅支撑枕套或其他床罩时保持常规枕头的外观。 芯可以由较高密度的粘弹性泡沫或弹性泡沫制成。 另一种产品可以是具有或不具有用于身体支撑的泡沫芯的床垫打包机,其承载在高气流粘弹性泡沫的板内。

    Product and process for tokens
    10.
    发明授权
    Product and process for tokens 失效
    令牌的产品和流程

    公开(公告)号:US06635143B2

    公开(公告)日:2003-10-21

    申请号:US10327159

    申请日:2002-12-20

    CPC classification number: B29C39/10 A44C21/00 B29C39/12

    Abstract: A token is manufactured using a combination of minting or casting operations and printing operations. The token comprises a metal base material that is minted or cast to the size and shape desired including embossed or debossed areas at selected locations on the token. In selected recessed or countersunk portions of the token, there are provided thin disks of material capable of carrying printed material such as single-colored or multi-colored pictures or indicia. The imprinted disk portions of the token are covered with a first protective coating and, optionally a second protective coating, that eliminates wear and tear on the printed areas of the token. Additionally or alternatively, the entire token can be covered with an outer coating to minimize wear and tear and preserve the unique designs carried by the token.

    Abstract translation: 令牌是使用铸造或铸造操作和打印操作的组合制造的。 令牌包括金属基材,其被铸造或铸造成所需的尺寸和形状,包括在令牌上的选定位置处的压花或凹陷区域。 在令牌的选定的凹入或埋头部分中,提供能够承载诸如单色或多色图片或标记的打印材料的材料的薄盘。 令牌的印刷盘部分被第一保护涂层和任选的第二保护涂层覆盖,其消除令牌的印刷区域上的磨损和撕裂。 另外或替代地,整个令牌可以用外涂层覆盖,以使磨损和撕裂最小化,并保留由令牌承载的独特设计。

Patent Agency Ranking